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Toxicology

Paumi Laboratory

Publications

Paumi CM, Chuk M, Chevelev I, Stagljar I, and Michaelis S. Yeast ABC Transporters and Their Interactors: New Technology that will Advance MRP Biology, MMBR Invited Review - Manuscript in Preparation

Paumi CM, Chuk M, Chevelev I, Stagljar I, and Michaelis S. Negative Regulation of the Yeast ABC Transporter, Ycf1p, by Phosphorylation within its N-Terminal Extension, Submitted April 1 2008 to JBC to J Biol Chem. 2008 Oct 3;283(40):27079-88.

Paumi CM, Engels K, Iyer K, Georgiev O, Michaelis S, and Stagljar I. Identification of Proteins that Interact with the Yeast MRP Transporter Ycf1p, Using the Membrane Yeast Two-Hybrid (MbYTH) Split-Ubiquitin System, Mol Cell. 2007 Apr 13;26(1):15-25.

O’Flaherty JT, Rogers LC, Paumi CM, Hantgan RR, Thomas LR, Clay CE, High KP, Chen YQ, Willingham MC, Kute TE, Rao A, Cramer SD, Morrow CS. 5-Oxo-ETE analogs and the proliferation of cancer cells. Biochim Biophys Acta. 2005 Oct 1;1736(3):228-36.

Paumi CM, Smitherman PK, Townsend AJ, Morrow CS. Glutathione S-Transferase (GSTs) Inhibit Transcriptional Activation by the Peroxisomal Proliferator-Activated Receptor g (PPARg) Ligand, 15-deoxy-delta (12,14)-prostaglandin J2 (15-d-PGJ­2). Biochemistry. 2004 Mar 2;43(8):2345-52.

Paumi CM, Wright M, Townsend AJ, Morrow CS. Multidrug resistance protein 1 (MRP1) and MRP3 attenuate cytotoxic and transactivating effects of cyclopentenone prostaglandin, 15-deoxy-delta (12,14)-prostaglandin J2 in MCF7 breast cancer cells. Biochemistry. 42:5429-5437 (2003)

Paumi CM, Ledford BG, Smitherman PK, Townsend AJ, Morrow CS. Role of multidrug resistance protein 1 (MRP1) and glutathione S-transferase A1-1 in alkylating agent resistance. Kinetics of glutathione conjugate formation and efflux govern differential cellular sensitivity to chlorambucil versus melphalan toxicity. J Biol Chem. 276:7952-6 (2001)

Hantgan RR, Paumi C, Rocco M, Weisel JW. Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on alphaIIbbeta3 integrin conformation and oligomerization. Biochemistry. 38:14461-74 (1999)

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