Thomas Tobin,
M.V.B. (D.V.M.)
Ph.D.
D.A.B.T.
Professor

Veterinary Science

College of Agriculture

Phone:
(859) 257-4757

Fax:
(859) 323-3981

e-mail:
ttobin@uky.edu 

Studies on the detection, action, uses and effects of drugs and medications in performance horse. Synthesis of critical drug metabolites and standards, development of ELISA tests for drugs and medications in racing horses, analytical chemistry including GC-MS and LC-MS analysis of drugs and medications and new recombinant DNA products used in racing and competition animals, quantification of pharmacological and therapeutic effects of drugs and medication in the horses and the clinical pharmacology and forensic toxicology of the horse. Current studies involve clinical and forensic pharmacology of local anesthetics, cocaine, vasodilators and amantadine and rimantadine and also agents used in the treatment of equine protozoal myelitis. Substantial intellectual property generated: books, immunoassay licensing, expert opinions. Honors include HBPA man of the Year, 1995. Over 250 research paper publications. books etc. on Toxicology, Clinical Veterinary and Forensic Pharmacology and related areas.

Research Publications/Presentations

Rees WA, Harkins JD, Woods WE, Blouin RA, Chambers T, Carter WG, Holland R, Fenger C, Tobin T: Amantadine and equine influenza Pharmacology, pharmacokinetics and neurological effects in the horse. In press. Equine Vet J 1996. [KY Ag Exp Sta #95-14-134]

Rees WA, Kwiatkowski S, Stanley SD, Granstrom DE, Yang J-M, Gairola CG, Diana JN, Glowczyk J, Woods WE, Tobin T: Development and characterization of an ELISA for trans-3-hydroxycotinine in biological fluids. In press to Bengston, DA, Henshel, DS (eds), Environmental Toxicology and Risk Assessment: Biomarkers and Risk Assessment (5^th Vol), Am Soc testing Materials, Philadelphia, In Press 1996.

Stanley SD, Sams RA, Harkins JD, Mundy GD, Boyles J, Woods WE, Tobin. T: Frequency distribution of pH values in post-race urines from throoughbreds and standardbreds: Research and regulatory significance. Equine Vet J, 27:471-473, 1995.

Tobin T, Mundy GD, Stanley DS, Sams RA, Crone D (eds): Testing for Therapeutic Medications, Environmental and Dietary Substances in Racing Horses, Proceedings of Workshop, Lexington, KY August 1994, 220 pages publ 1995. [KY Ag Exp Sta#95-14-058]

Harkins JD, Stanley SD, Mundy GD, Carney JM, Sams RA, Woods WE, Tobin T: Pharmacology and pharmacokinetics of local anesthetics in the horse and their regulatory control. J Vet Pharmacol Therap. 18: pp397-406. 1995.

Stanley S, Wood T, Goodman JP, Henry PA, Woods WE, Chang S-L, Tai H-H, Watt D, Kwiakowski S, Blake JW, Tobin T: Immunoassay detection of drugs in racing horses: Detection of ethacrynic acid and bumetanide in equine urine by ELISA. J Analytical Tox, 18:95-100, 1994.