Brent D. Palmer,
PhD.
Professor
Biological Sciences
Phone:
(859) 257-5673
Fax:
(859) 257-1717
e-mail:
bpalmer@uky.edu
Web page:
http://biology.uky.edu/palmer
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Research Interests
My research program focuses on conservation of wildlife species. Reproduction is the critical life stage that enables a species to propogate itself and ensure survival of the species. Anything that impairs reproduction may lead to population decline and ultimately to extinction. I am a comparative reproductive biologist and endocrinologist specializing in lower vertebrates. Many common pollutants, such as pesticides and industrial chemicals, disrupt the endocrine system by binding to hormone receptors in either an agonistic or antagonistic fashion, thereby altering endogenous hormonal signals. These environmental endocrine disrupters have the ability to severely impact adult reproduction and embryonic development. Embryos are particularly sensitive to endocrine disrupting effects since they use hormonal signals to direct the development of anatomical systems and establish physiological set points. My research program uses comparative vertebrate reproductive endocrinology and functional morphology to investigate mechanisms of action of environmental endocrine disrupters and their effects on wildlife populations, particularly on amphibians and reptiles. In addition, my research program uses an integrative approach to investigate the evolution of reproductive modes, such as oviparity and viviparity.
Research Publications/Presentations
J.S. Rehage, S.G. Lynn, J.I. Hammond, B.D. Palmer and A. Sih.
2002. Effects of larval exposure to triphenyltin on the survival,
growth, and behavior of larval and juvenile Ambystoma barbouri. Environmental
Toxicology and Chemistry, 21(4):807-15.
Rohr, J.R., A.A. Elskus, B.S. Shepherd, P.H. Crowley, T.M. McCarthy, J.H.
Niedzwiecki, T. Sager, A. Sih, B.D. Palmer. 2003. Lethal and
sublethal effects of atrazine, carbaryl, endosulfan, and octylphenol on the
Streamside Salamander, Ambystoma barbouri. Environmental
Toxicology and Chemistry 22(10):2385-2392.
Palmer, B.D. 2000. Anatomy and Physiology of Reptiles.
In: The Ecotoxicology of Amphibians and Reptiles. Sparling, DW,
G. Linder, and C.A. Bishop (eds). 2000. Ecotoxicology of Amphibians
and Reptiles. Soc.
Environ. Toxicol. Chem. Press, Pensacola, FL, USA. Pp. 111-139.
Selcer, K.W., S. Nagaraja, P. Foret, D. Wagner, L. Williams, and B.D.
Palmer. 2001. Vitellogenin as a biomarker for estrogenic
chemicals: development of antibodies and primers with broad species
applications. In: PCBs: Recent Advances in the Environmental
Toxicology and Health Effects. L.W. Robertson and L.G. Hansen (ed.).
University of Kentucky Press, Lexington, KY. pp. 285-292.
Palmer,
B.D.
2002. In: State of the Science on Endocrine Disruptors.
Edited by: Terri Damstra, Sue Barlow, Aake Bergman, Robert Kavlock, Glen
Van Der Kraak. International Program on Chemical Safety. World
Health Organization. 54
pages. http://ehp.niehs.nih.gov/who.
Palmer, B.D. and K.W. Selcer. 1996. Vitellogenin as a Biomarker for
Xenobiotic Estrogens: A Review. In: Environmental Toxicology and Risk Assessment, Vol. 5. D.A. Bengtson and D.S. Henshel, eds. American Society
for Testing and Materials, STP 1306, Philadelphia. pp. 3-22.
Guillette, L.J., Jr., A.R. Woodward, D.A. Crain, G.R. Masson, B.D. Palmer,
M.C. Cox, Q. You-Xiang, and E.F. Orlando. 1997. The reproductive cycle of
the female American alligator (Alligator mississippiensis). General and
Comparative Endocrinology,108:87-1997.
Palmer, B.D., M.J. Perkins, K. Massie, M.S. Simon, M.C.A. Uribe. 1997.
Reproductive anatomy and physiology of reptiles: evolutionary and
ecological perspectives. In: The Biology, Husbandry and Health Care of
Reptiles and Amphibians. Vol. 1: Reptiles. L. Ackerman (ed.). TFH
Publications. pp. 54-87.
Palmer, B.D., L.K. Huth, D.L. Pieto, and K.W. Selcer. 1998. Vitellogenin
as a biomarker for xenobiotic estrogens in an amphibian model system.
Environmental Toxicology and Chemistry, 17(1):30-36.
Uribe, M.C.A., G. Gonzalez-Porter, B.D. Palmer, and L.J. Guillette, Jr.
1999. Cyclic histological changes of the oviductal-cloacal juncture in the
viviparous snake Toluca lineata.. J. Morphol. 237:91-100.
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