University of Kentucky |  UK HealthCare |  News & Events |  Give to Medicine |  About Our College |  Diversity  |   Anonymous Questions 
UK College of Medicine logo Link to the College of Medicine web site

Department of Surgery

DEPARTMENT

CHAIRMAN

DIVISIONS

EDUCATION

RESEARCH

PATIENT SERVICES

ADMINISTRATION

SURGERY NEWS

THE BLUEGRASS

Clinical Faculty Research Faculty Residency Clinics

KYPRIANOU LAB & KEY PUBLICATIONS

Tang X, Tang X, Gal J, Kyprianou N, Zhu H and Tang G. Detection of microRNAs in prostate cancer cells by microRNA array. Methods Mol Biol 2011;732:69-88.

Sakamoto S, Schwarze S and Kyprianou N. Anoikis disruption of focal adhesion-akt signaling impairs renal cell carcinoma. Eur Urol 2011 May;59(5):734-44.

Martin SK and Kyprianou N. Gene fusions find an ERG-way to tumor inflammation. Cancer Biol Ther 2011 Feb 15;11(4):418-20.

Wang WX, Kyprianou N, Wang X and Nelson PT. Dysregulation of the mitogen granulin in human cancer through the miR-15/107 microRNA gene group. Cancer Res 2010 Nov 15;70(22):9137-42.

Zhu ML, Horbinski CM, Garzotto M, Qian DZ, Beer TM and Kyprianou N. Tubulin-targeting chemotherapy impairs androgen receptor activity in prostate cancer. Cancer Res 2010 Oct 15;70(20):7992-8002.

Zhu M, Partin JV, Bruckheimer EM, Strup SE and Kyprianou N. TGF-beta signaling and androgen receptor status determine apoptotic cross-talk in human prostate cancer cells. The Prostate 2008;68:287-95.

Sakamoto S, Ryan AJ and Kyprianou N. Targeting vasculature in urologic tumors: current therapeutic value. J Cell Biochem 2008;103(3):691-70.

Garrison JB, Shaw Y-J, Chen C-S and Kyprianou N. Novel quinazoline-based compounds impair prostate tumorigenesis by targeting tumor vascularity. Cancer Res 2007;67:11344-52.

Harris AM, Warner BW, Wilson JM, Becke A, Rowland RG, Conner W, Lane M, Kimbler K, Durbin EB, Baron AT and Kyprianou N. Effect of alpha-1-adrenoceptor antagonist exposure on prostate cancer incidence: an observational cohort study. J Urology 2007;178(5):2176-80.

Sutton TM, Yingling M, Vyas A, Atiemo H, Borkowski A, Jacobs SC and Kyprianou N. Finasteride targets prostate tissue vascularity by inhibiting cell adhesion and inducing apoptosis. The Prostate 2006;66:1194-1202.

McKenzie S and Kyprianou N. Apoptosis evasion in prostate tumorigenesis: significance in therapeutic resistance. J Cell Biochem 2006;97:18-32.

Garrison JB and Kyprianou N. Doxazosin induces anoikis of benign and malignant prostate epithelial cells via a death receptor mediated pathway. Cancer Res 2006;66:464-72.

Zhu B, Fukada K, Zhu H and Kyprianou N. Prohibitin and Cofilin are intracellular effectors of TGF-? signaling in prostate cancer cells. Cancer Res 2006;66:8640-47.

Rennebeck G, Martelli M and Kyprianou N. Anoikis and survival connections in the tumor microenvironment: is there a role in prostate cancer metastasis. Cancer Res 2005;65:11230-35.

Keledjian K, Garrison BJ and Kyprianou N. Doxazosin inhibits vascular endothelial cell adhesion, migration and invasion. J Cell Biochem 2005;94:374-88.

Shaw Y-J, Yang Y-T, Garrison JB, Kyprianou N and Chen C-S. Pharmacological exploitation of the alpha1 adrenoceptor antagonist doxazosin to develop a novel class of apoptosis-targeting antitumor agents that block intracellular protein kinase B/Akt activation. J Med Chem 2004;47:4453-62.

Comments and Corrections |  An Equal Opportunity University |  Jobs  |  Terms, Conditions and Accessibility Statements   |  Privacy
© 2011, University of Kentucky College of Medicine, 138 Leader Ave., Lexington, Kentucky, USA 40506-9983
Student Affairs: (859) 323-5261 · Admissions: (859) 323-6161 · Clinical Questions: (859) 257-1000 · Dean's Office: (859) 323-6582
Page last updated Monday, June 06, 2011