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KYPRIANOU LAB & KEY PUBLICATIONS

Tang X, Tang X, Gal J, Kyprianou N, Zhu H and Tang G. Detection of microRNAs in prostate cancer cells by microRNA array. Methods Mol Biol 2011;732:69-88.

Sakamoto S, Schwarze S and Kyprianou N. Anoikis disruption of focal adhesion-akt signaling impairs renal cell carcinoma. Eur Urol 2011 May;59(5):734-44.

Martin SK and Kyprianou N. Gene fusions find an ERG-way to tumor inflammation. Cancer Biol Ther 2011 Feb 15;11(4):418-20.

Wang WX, Kyprianou N, Wang X and Nelson PT. Dysregulation of the mitogen granulin in human cancer through the miR-15/107 microRNA gene group. Cancer Res 2010 Nov 15;70(22):9137-42.

Zhu ML, Horbinski CM, Garzotto M, Qian DZ, Beer TM and Kyprianou N. Tubulin-targeting chemotherapy impairs androgen receptor activity in prostate cancer. Cancer Res 2010 Oct 15;70(20):7992-8002.

Zhu M, Partin JV, Bruckheimer EM, Strup SE and Kyprianou N. TGF-beta signaling and androgen receptor status determine apoptotic cross-talk in human prostate cancer cells. The Prostate 2008;68:287-95.

Sakamoto S, Ryan AJ and Kyprianou N. Targeting vasculature in urologic tumors: current therapeutic value. J Cell Biochem 2008;103(3):691-70.

Garrison JB, Shaw Y-J, Chen C-S and Kyprianou N. Novel quinazoline-based compounds impair prostate tumorigenesis by targeting tumor vascularity. Cancer Res 2007;67:11344-52.

Harris AM, Warner BW, Wilson JM, Becke A, Rowland RG, Conner W, Lane M, Kimbler K, Durbin EB, Baron AT and Kyprianou N. Effect of alpha-1-adrenoceptor antagonist exposure on prostate cancer incidence: an observational cohort study. J Urology 2007;178(5):2176-80.

Sutton TM, Yingling M, Vyas A, Atiemo H, Borkowski A, Jacobs SC and Kyprianou N. Finasteride targets prostate tissue vascularity by inhibiting cell adhesion and inducing apoptosis. The Prostate 2006;66:1194-1202.

McKenzie S and Kyprianou N. Apoptosis evasion in prostate tumorigenesis: significance in therapeutic resistance. J Cell Biochem 2006;97:18-32.

Garrison JB and Kyprianou N. Doxazosin induces anoikis of benign and malignant prostate epithelial cells via a death receptor mediated pathway. Cancer Res 2006;66:464-72.

Zhu B, Fukada K, Zhu H and Kyprianou N. Prohibitin and Cofilin are intracellular effectors of TGF-? signaling in prostate cancer cells. Cancer Res 2006;66:8640-47.

Rennebeck G, Martelli M and Kyprianou N. Anoikis and survival connections in the tumor microenvironment: is there a role in prostate cancer metastasis. Cancer Res 2005;65:11230-35.

Keledjian K, Garrison BJ and Kyprianou N. Doxazosin inhibits vascular endothelial cell adhesion, migration and invasion. J Cell Biochem 2005;94:374-88.

Shaw Y-J, Yang Y-T, Garrison JB, Kyprianou N and Chen C-S. Pharmacological exploitation of the alpha1 adrenoceptor antagonist doxazosin to develop a novel class of apoptosis-targeting antitumor agents that block intracellular protein kinase B/Akt activation. J Med Chem 2004;47:4453-62.

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