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Radiation Medicine

GENERAL

EDUCATION
RESEARCH

CLINICAL SERVICES

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Photo of Dr. Kudrimoti Mahesh R. Kudrimoti, M.D.
Professor
Vice-Chair for Clinical Operations
Residency Program Director

Department of Radiation Medicine
Chandler Medical Center, Pavilion H
800 Rose Street C-111
Lexington, KY 40536-0293
Phone: (859) 323-6486
Fax: (859) 257-7483
Email: mkudr0@email.uky.edu

 

 

 

CLINICAL INTERESTS:

  • Pancreatic-Biliary, Hepatic Cancer, Neuroendocrine Cancers
  • Gynecologic Cancer
  • Head and Neck Cancer, Thyroid Cancers
  • Brachytherapy, Sir Spheres
  • Skin Cancer and Melanomas

EDUCATION:

  • M.D., Radiation Oncology, 2001
  • M.D., Radiotherapy (PGIMER, Chandigarh, India), 1995
  • M.D., MBBS, (Osmania Medical College, Hyderabad, India), 1992

BOARD CERTIFICATION:

American Board of Radiology, Radiation Oncology, 2003

SELECTED PUBLICATIONS:

Sathishkumar S, Boyanovsky B, Karakashian AA, Rozenova K, Giltiay N, Kudrimoti M, Mohiuddin M, Ahmed MM, and Nikolova-Karakashian M. Elevated Sphingomyelinase Activity and Ceramide Concentration in Serum of Patients Undergoing High Dose Spatially Fractionated Radiation Treatment: Implications for Endothelial Apoptosis. Cancer Biology & Therapy 4(9): 979-986, 2005.

Spring P, Valentino J, Armold S, Sloan D, Kenady D, Kudrimoti M, Haydon R III , Lee C, Given S, Mohiuddin M, and Regine W. Long-term results of hyperfractionated radiation and high-dose intraarterial cisplatin for unresectable oropharyngeal carcinoma. Cancer 104(8): 1765-1771, 2005.

Doty J, Gossman D, Kudrimoti M, Valentino J, and Spring P. Analysis of Unknown Primary Carcinoma Metastatic to the Neck: Diagnosis, Treatment and Outcomes.  KMA Journal, 104 (2): 57-64, Feb. 2006.

Sathishkumar S, Boyanovsky B, Karakashian A, Rozenova K, Giltiay N, Kudrimoti M, Mohiuddin M, Ahmed M, Nikolova-Karakashian M. Elevated Sphingomyelinase Activity and Ceramide Concentration in Serum of Patients Undergoing High Dose Spatially Fractionated Radiation Treatment: Implications for Endothelial Apoptosis.  Cancer Biol Ther. 2005 Sep; 4(9):979-86. Epub 2005 Sep 13.

Huhn JL, Regine WF, Valentino J, Meigooni AS, Kudrimoti M, Kenady D, Sloan D, Spring P, Mohiuddin M. Spatially fractionated GRID radiation treatment of advanced neck disease associated with head and neck cancer.  TCRT, December, 2006; 5(6), 607-12.

Kudrimoti M. Genetic markers predictive of response to induction chemoradiotherapy for locally advanced rectal cancers, J of KY Medical Association, Jan. 2007, 105(1) 18-22.

Warren G, Grimes K, Xu Y, Kudrimoti M, St. Clair W. Selectively enhanced radiation sensitivity in prostate cancer cells associated with proteasome inhibition, Oncology Reports, 15: 1287-1291, May 2006.

Meigooni, AS, Gnaster M, Dou K, Johnson EL, Meigooni NJ, Kudrimoti M.  Dosimetric evaluation of parallel opposed spatially fractionated radiation therapy of deep-seated bulky tumors.  Medical Physics, Feb. 2007; 34 (2):599-603.

Baker C, Dini SA, Kudrimoti M, Awan SB, Meigooni AS.  Dosimetric evaluation of a new designed low dose rate brachytherapy applicator for treatment of cervical cancer with extension into the lower vagina.  J Appl Clin Med Phys 2007; 8 (2):37-46.

Berk L, Berkey B, Rich T, Hrushesky W, Blask D, Gallagher M, Kudrimoti M, McGarry RC, Suh J, Mehta M.  Randomized phase II trial of high-dose melatonin and radiation therapy for rpa class 2 patients with brain metastases (RTOG 0119).  Int J Radiat Oncol Biol Phys. April 2007.

William F. Regine, MD; Kathryn A. Winter, MS; Ross A. Abrams, MD; Howard Safran, MD; John P. Hoffman, MD; Andre Konski, MD; Al B. Benson, MD; John S. Macdonald, MD; Mahesh R. Kudrimoti, MD; Mitchel L. Fromm, MD; Michael G. Haddock, MD; Paul Schaefer, MD; Christopher G. Willett, MD; Tyvin A. Rich, MD Fluorouracil vs Gemcitabine Chemotherapy Before and After Fluorouracil-Based Chemoradiation Following Resection of Pancreatic Adenocarcinoma .A Randomized Controlled Trial JAMA. 2008; 299(9):1019-1026.

Linda S. Elting, Dorothy M. Keefe, Stephen T. Sonis, Adam S. Garden, F. K. L. Spijkervet, Andrei Barasch, Roy B. Tishler, Thomas P. Canty, Mahesh K. Kudrimoti, Montserrat Vera-Llonch, for the Burden of Illness Head and Neck Writing Committee. Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy. Cancer. Volume 113, Issue 10, Pages: 2704-2713.

Kudrimoti M, Arnold S, Valentino J, Rangnekar V, Randall M, Warren GW.  Assessment of Nicotine Exposure in Head and Neck Cancer Patients during Treatment with Radiotherapy or Chemoradiotherapy, Proceedings of the American Society for Radiation Oncology 51st Annual Meeting, 75(3) S1:S431-S432, 2009.

Warren GW, Kudrimoti MR, Rangnekar V. The Adverse Effects of Nicotine on Chemotherapy and/or Radiotherapy in Cancer Treatment.  Proc Soc Res Nicotine Tobacco 1654, 2010.

Warren GW, Singh A, Randall M, McGarry R, Kudrimoti M, Rangnekar V. Prognostication Using Hif-1 alpha May Require Simultaneous Nicotine Assessment. Proc Am Assoc Cancer Res S352:2010.

Warren GW, Randall M, McGarry R, Kudrimoti M, Rangnekar V. Nicotine Decreases the Therapeutic Efficacy of Radiotherapy and Chemoradiotherapy In Vivo. Proc Am Assoc Cancer Res S218:2010.

Warren GW, Arnold SM, Valentino J, Randall M, Kudrimoti M. A rationale and model for tobacco and nicotine assessment during cancer treatment. J Clin Oncol 28: el2034, 2010.

Kudrimoti M, Arnold SM, Valentino J, Randall M, Warren GW. Longitudinal self-reported and serum based assessment of tobacco or nicotine use in head and neck cancer patients during definitive radiotherapy or chemoradiotherapy.  J Clin Oncol 28:176S, 2010.

Irwin D, Dong L, ShangY, Cheng R, Kudrimoti M, Stevens SD, and Yu G. Influences of tissue absorption and scattering on diffuse correlation spectroscopy blood flow measurements. Biomedical Optics Express, 2:7, 2011.

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