Spring 2008 MN-463, Chandler Medical Center
Wednesdays at 3:00 p.m. (unless otherwise noted)

Date	Speaker	Title	Host
January 9	Charlotte A. Peterson, Ph.D. Associate Dean for Research College of Health Sciences University of Kentucky	Regulation of myogenic differentiation potential by Wnt signaling in aging and cancer	Mike Reid
January 16	Chemyong Jay Ko, Ph.D. Associate Professor Center of Excellence in Reproductive Sciences University of Kentucky	Regulation of ovulation: estrogens and endothelins.
January 23	Michael W. Fannon, Ph.D. Assistant Professor Department of Ophthamology and Visual Sciences University of Kentucky	Regulating the bioavailability of heparin binding molecules
January 30	Ken Abe, Ph.D. Department of Physiology and Biophysics Georgetown University	Platelet NPY in Stress Induced Neointima Formation.
February 6	Romulo Alburquerque Jorge Gamboa Department of Physiology University of Kentucky	A Novel Endogenous Inhibitor of Lymphangiogenesis Skeletal muscle adaptationto hypoxia Graduate Students Seminar
February 13	James M. Ervasti, Ph.D. Professor Department of Biochemistry, Molecular Biology and Biophysics University of Minnesota	Dystrophin, Actin and Human Disease.	Gregory Frolenkov
February 20 MN-263	Todd Trappe, Ph.D. Associate Professor of Physical Education Ball State University	Influence of Exercise and Cyclooxygenase Inhibitors on the Adaptive Response of Skeletal Muscle and Tendon in Humans	Health Sciences
February 27 MN-363 11:00 a.m.	Frank Porreca, Ph.D. Professor Pharmacology and Anesthesiology University of Arizona	Persistent restoration of sensory function by systemic artemin following dorsal root injury	Karin High
March 5	Randall R. Reed, Ph.D. Professor Department of Molecular Biology and Genetics and Department of Neuroscience Investigator Howard Hughes Medical Institute The John Hopkins University School of Medicine	Stem Cells and Smell Cells: The Developmental Pathways and Cellular Specializations Underlying Olfaction	Tim McClintock
March 12 MN-463 10 a.m.	Wolfgang Liedtke, M.D, Ph.D. Assistant Professor Duke University Medical Center	TRPV4-mediated signal transduction - news and views	Sean Stocker
March 19	Randy J. Seeley, Ph.D. Professor of Psychiatry Genome Research Institute University of Cincinnati	How obesity went to our heads: CNS regulation of body weight	Sean Stocker
March 26	Shawn Crump Robert Hunt Department of Physiology University of Kentucky	Cardiomyocyte Cav1.2 protein expression as a target of ICa, L regulation. Controlled cortical impact: A mouse model of post-traumatic epilepsy. Graduate Student Seminar
April 2	Paul Fuchs, Ph.D. John E. Bordley Professor Director of Research Otolaryngology Head and Neck Surgery Co-Director Center for Sensory Biology Johns Hopkins University School of Medicine	Nicotinic inhibition of the cochlea: a calcium store conundrum	Gregory Frolenkov
April 9	Karin High, Ph.D. Professor Department of Physiology University of Kentucky	Vicious Cycles of Pain and Inflammation
April 16 MN-263	Liming Ling, Ph.D. Assistant Professor of Medicine Harvard School of Medicine	Sleep fragmentation impairs respiratory control via adenosine A1 receptors	Dexter Speck
April 23	Charles M. Grisham, Ph.D. Professor Department of Chemistry University of Virginia	Emerging Paradigms in Biochemistry	Graduate Students
April 30 MN-263	Amanda Trout Department of Physiology University of Kentucky	Regulation of ER alpha in the Cortex Following Ischemic Injury. Graduate Students Seminar
May 7	Karl B. Thor, Ph.D. Vice President of Research Urogenix, Inc.	Electrophysiological and molecular studies ofm onoamine receptor systems in CNS control of urethral rhabdosphincter	Sasha Rabchevsky

Fall 2008 MN-463, Chandler Medical Center
Wednesdays at 3:00 p.m. (unless otherwise noted)

Date	Speaker	Title	Host
August 13	Dennis Karounos, M.D. Associate Professor Internal Medicine UK College of Medicine Division of Endocrinology and Molecular Medicine	Insights into the Prevention of Diabetes and its Complications: Results of Recent Clinical Trials
August 27	Suzanne Doolen, Ph.D. Spinal Cord Society Research Center	Beneficial effects of statins (HMG CoA-reductase inhibitors) on CNS trauma	Brad Taylor
September 10	George M. Smith, Ph.D. Professor Department of Physiology University of Kentucky	Tom Tom for axon: directing axon growth along molecular highways.
September 17	Karyn Esser, Ph.D. Associate Professor Department of Physiology University of Kentucky	The molecular clock and myod: transcriptional network for skeletal muscle maintenance
September 24	Ruben Stepanyan, Ph.D. Department of Physiology University of Kentucky	TRPA1 regulates the function of cochlear outer hair cells
October 8	Kevin P. Campbell, Ph.D. Professor Physiology and Biophysics University of Iowa Investigator Howard Hughes Medical Institute	Maintenance of Muscle Cell Membrane Integrity and the Pathogenesis of Muscular Dystrophy	Karyn Esser
October 15	Scott Brady, Ph.D. Professor and Head Department of Anatomy and Cell Biology University of Illinois at Chicago	Life in the Fast Lane: Regulation of Fast Axonal Transport and Neurodegeneration	George Smith
October 22	Richard E. Klabunde, Ph.D. Associate Professor Ohio University	Teaching Physiology in a Changing World of Medical Education	David Randall
October 29	Roger A. Fielding, Ph.D. Senior Scientist and Director Nutrition, Exercise Physiology & Sarcopenia Laboratory Tufts University	The role of exercise and physical activity on functional limitations and disability in older adults.	Charlotte Peterson
November 5 MN-563 10-11 am.	Kevin Davy, Ph.D. Associate Professor Virginia Tech University	Are we becoming sympathetic to the obesity epidemic?	Sean Stocker
November 12	Grace K. Pavlath, Ph.D. Professor Department of Pharmacology Emory University	Molecular and Cellular Control of Muscle Growth	Karyn Esser
November 19	Kenneth Campbell, Ph.D. Assistant Professor University of Kentucky	Spatially-explicit models of muscle function: computational tools for studying disease
December 3	Neeraja Sammeta, Ph.D. Department Of Physiology University of Kentucky	Uncx, a paired homeobox transcription factor, regulates olfactory neurogenesis and neuronal survival
December 10	Richard Moss, Ph.D. Professor and Chair Department of Physiology University of Wisconsin	Myosin binding protein C: a critical modulator of contraction kinetics in myocardium	Ken Campbell
December 17	Vincent Cassone, Ph.D. Professor and Chair of Biology University of Kentucky	Time and Time Again: Molecular, Cellular and Behavioral Bases for Biological Time-Keeping	Karyn Esser

Spring 2009 MN-263, Chandler Medical Center
Wednesdays at 3:00 p.m. (unless otherwise noted)

Date	Speaker	Title	Host
January 7	Dana Gaddy, Ph.D. Associate Professor Department of Physiology University of Arkansas for Medical Sciences	Skeletal Adaptation to Aging, Disuse and Reloading	Esther Dupont-Versteegden
January 14	Andrea Zsombok, Ph.D. Department of Physiology University of Kentucky	TRPV1 receptor plasticity in the brain during type 1 diabetes.	Bret Smith
January 21	Christopher L. Mendias, Ph.D. University of Michigan	Preventing skeletal muscle fibrosis and atrophy by the therapeutic inhibition of myostatin	Charlotte Peterson
January 28 Re-Scheduled due to inclement weather	William Lester Department of Physiology University of Kentucky	Calcium sparks in embryonic cardiac myocytes: Using development to understand disease.
February 4	Glenn C. Telling, Ph.D. Professor Departments of Microbiology Immunology & Molecular Genetics University of Kentucky	Kentucky Fried Prions	Gregory Frolenkov
February 11	John R. Thelin, Ph.D. University Research Professor History of Higher Education & Public Policy Educational Policy Studies University of Kentucky	Great expectations: American higher education's prospects and problems in the 21st century	Dave Randall
February 18	Jeffrey R. Martens, Ph.D. Assistant Professor Department of Pharmacology University of Michigan	Ciliary Trafficking of Olfactory Signaling Proteins: linking sensory function and disease	Tim McClintock
February 25	Pieter de Tombe, Ph.D. Professor and Chairman Department of Physiology Loyola University, Chicago	Sarcomere Dynamics in Health and Disease	Marius Sumandea
March 4	Jeremy McIntyre Department of Physiology University of Kentucky	Emx2 stimulates Odorant Receptor gene expression
March 11	Håkan Westerblad, Ph.D. Professor Department of Physiology and Pharmacology Karolinska Institutet, Sweden	Reactive oxygen/nitrogen species, friends or foes? Studies in skeletal and cardiac muscle	Mike Reid
March 18 MN-263 11:00 a.m.	Donald Bers, Ph.D. Professor and Chairman Department of Pharmacology University of California, Davis	CaMKII in Cardiac Myocytes: Roles in Arrhythmogenesis and Transcriptional Regulation	Jonathan Satin
March 25	Gretchen Wolff & Carmen Kiper Department of Physiology University of Kentucky	Regulation of the Molecular Clock: Photic and Nonphotic Timing Cues Calcium channels in adult cardiomyocyte differentiation and maturation
April 1	Fanmuyi Yang & Chen Zhang Department of Physiology University of Kentucky	Transverse Aortic Constriction: A Model of Left Ventricular Hypertrophy and Coronary Inflammation Reconstruction of Nigrostriatal Pathway
April 8	Christa Muller-Sieburg, Dr. rer. nat. Professor Sidney Kimmel Cancer Research Center La Jolla, CA	Genetic and Epigenetic Regulation of Hematopoietic Stem Cells	Gary Van Zant
April 15 MN 363	Inna A. Belyantseva, Ph.D. Staff Scientist National Institute on Deafness and Other Communication Disorders National Institutes of Health	Rethinking the function of gamma-actin: insight from inner ear research	Gregory Frolenkov
April 22 MN 363	Zubair Ahmed, Ph.D. Assistant Professor Dept. of Ophthalmology Dept. of Otolaryngology Cincinnati Children's Hospital Medical Center	Mutations of LRTOMT, a fusion gene encoding two proteins, cause nonsyndromic deafness	Gregory Frolenkov
April 29	Laura Ashley & Megan Bardgett Department of Physiology University of Kentucky	Doxorubicin acts through TNFR1 to cause murine skeletal muscle dysfunction Insulin: How it Acts Centrally to Activate the Sympathetic Nervous System
May 6	Brendan J. Canning, Ph.D. Associate Professor of Medicine The Johns Hopkins University	Encoding of the Cough Reflex	Lu-Yuan Lee
May 13	Timothy McClintock, Ph.D. Professor Department of Physiology University of Kentucky	Molecular Systems Physiology: Beyond gene expression atlases.
May 20	Naomi Brooks, Ph.D. Department of Physiological Sciences Stellenbosch University, South Africa	Myostatin and SMADs in hibernating squirrel muscle	Karyn Esser
May 27	William Lester Department of Physiology University of Kentucky	Calcium sparks in embryonic cardiac myocytes: Using development to understand disease.
June 25	Lindsay B. Hough, Ph.D. Professor and Associate Director Neuropharmacology Albany Medical College	Significance of Brain Epoxygenase Pathways for Analgesic Drug Action	Brad Taylor

Fall 2009 MN-463, Chandler Medical Center
Wednesdays at 3:00 p.m. (unless otherwise noted)

Date	Speaker	Title	Host
September 9	Zachary B Fulkerson Graduate Student Department of Physiology University of Kentucky	Interaction of Autotaxin (Lysophospholipase D) with Platelet Integrins: A Possible Mechanism of Localizaing Enzymatic Activity
September 17 MN 463 3:00 p.m.	Kathleen A. Sluka, Ph.D., PT Professor University of Iowa	The role of acid-sensing ion channels in musculoskeletal pain	Karin High
September 23 Cancelled	Jon Satin, Ph.D. Associate Professor Physiology Department University of Kentucky	Cancelled
September 30	Jon Satin, Ph.D. Associate Professor Physiology Department University of Kentucky	In search of model systems to evaluate the L-type calcium channel transcription factor: an ion channel, and a transcription regulator
October 7 Cancelled	Garret A. FitzGerald, M.D. Chair Department of Pharmacology University of Pennsylvania School of Medicine	Cancelled	Ming Gong
October 14	Shin Yamazaki , Ph.D. Research Associate Professor of Biological Sciences Vanderbilt University	Complex Organization of the Mammalian Circadian System: Luminescence Reporter Techniques Now and Then	Gretchen Wolff
October 21	Andrew Brack, Ph.D. Assistant Professor of Medicine Harvard Medical School	Self Renewal of Muscle Stem Cells During Regeneration	Charlotte Peterson
October 28	Kathryn Saatman, PhD Associate Professor Department of Physiology University of Kentucky	Insulin-like Growth Factor-1 as a Neuroprotective Strategy for Traumatic Brain Injury
November 4	Hiroshi Saito, Ph.D. Assistant Professor Department of Surgery University of Kentucky	Inflammation, Oxidative Stress, Coagulation, and Aging	Charlotte Peterson
November 11	David T. Yue, MD, PhD Professor Biomedical Engineering and Neuroscience Johns Hopkins University	Enzyme-inhibitor-like tuning of Ca2+ channel connectivity with calmodulin	Jon Satin/Shawn Crump
November 18	Andrew Judge, PhD University of Florida	Heat shock proteins and muscle atrophy	Esther E. Dupont-Versteegden
December 2	Marcielle De Beer, PhD Associate Professor Department of Physiology University of Kentucky	HDL and inflammation	Mike Reid
December 9	Stephen Byers, PhD Professor Associate Director for Shared Resources Dept. Oncology, Georgetown University	Sunlight, zebrafish, microtubules and cancer	Yi Liu / Garry Van Zant
December 16	Debbie C. Thurmond, PhD Associate Professor of Biochemistry and Molecular Biology Indiana University	TBA	Valerie Reeves / Eric Smart

Spring 2010 MN-463, Chandler Medical Center
Wednesdays at 3:00 p.m. (unless otherwise noted)

Date	Speaker	Title	Host
January 13	Adrian Fischl Department of Physiology University of Kentucky	S100A5 is an activity-dependent gene in olfactory sensory neurons	Tim McClintock
January 20	Bradley K. Taylor, PhD Associate Professor Dept. Physiology University of Kentucky	Rapid inhibition of neuropathic pain through spinal PPARγ receptors
January 27	Bruce Damon, PhD Assistant Professor Radiology and Radiological Sciences Molecular Physiology & Biophysics Vanderbilt University	Physiological Magnetic Resonance Imaging of Skeletal Muscle In Vivo	Karyn Esser
February 3	Brad Keller, MD Kosair Charities Chair in Pediatric Heart Surgery Research University of Louisville	Insights from Embryos into the Causes and Treatments for Congenital Heart Disease	Jon Satin
February 10	Kumble R. Subbaswamy, PhD Provost University of Kentucky	Innovation in Education	Education Committee and PGY-TEAM
February 17	Kenneth McCarson, PhD Associate Professor Department of Pharmacology University of Kansas Medical Center	Plasticity of Central Pain Signaling, or “Hmm, that didn’t hurt before . . .”	Brad Taylor
February 24	Richard C. Vari, PhD Associate Dean for Medical Education Virginia Tech Carilion School of Medicine	What if you create a medical school with a clean slate?	Brian Jackson
March 3	Silvia S. Blemker, PhD Assistant Professor of Biomedical Engineering University of Virginia	Skeletal muscle structure and function explored through computational modeling	Ken Campbell Karyn Esser
March 10	Gabrielle Kardon, PhD Department of Human Genetics University of Utah	Development of the vertebrate musculature: the role of Tcf4 and connective tissue fibroblasts	Karyn Esser
March 17 12:00 p.m MN 363	Vance Lemmon, Ph.D. Professor and Chair in Developmental Neuroscience University of Miami	Functional Genomics: Phenotypic screening of large gene sets to identify genes that regulate axon growth and branching	George Smith
March 24 Cancelled	John T. Fisher, Ph.D. Professor and Head Department of Physiology Queen's University	TRPV1 and muscarinic airway innervation: insight from murine phenotypes	Lu-Yuan Lee
March 31	Charles Chalfant, PhD. Associate Professor Department of Biochemistry Virginia Commonwealth University	Ceramide-1-phosphate: The missing link in eicosanoid biosythesis and inflammation	Mariana Karakashian
April 7	James A. Spudich, Ph.D. Professor of Biochemistry Stanford University	Nature's exquisite nanomachines: The myosin family of molecular motors	Ken Campbell
April 14	Vjekoslav Miletic, Ph.D. Professor University of Wisconsin, Madison	Spinal Dorsal Horn Plasticity and Neuropathic Pain	Brad Taylor
April 22 3:00 pm MN 563	Mellani Lefta Department of Physiology University of Kentucky	Contribution of the circadian clock gene, Bmal1, in the development of dilated cardiomyopathy
April 28	Kathleen Schoch Shaun Carlson Department of Physiology University of Kentucky	Calpastatin overexpression as a therapeutic target for traumatic brain injury And Neuroprotective and Neuroreparative Potential of Insulin-Like Growth Factor-1 after Traumatic Brain Injury
May 5	Valerie Reeves Chris Simmons Department of Physiology University of Kentucky	Stearic Acid: The Diabetes Fighting Fat And The Genetic Epidemiology of Alzheimer's Disease - Ties to Cholesterol and Autoimmunity
May 12	Cheryl L. Stucky, Ph.D. Associate Professor Dept. Cell Biology, Neurobiology and Anatomy Medical College of Wisconsin	TRPA1 and Mechanotransduction: A touchy subject	Brad Taylor
May 19	William D. Willis, MD, PhD Professor Department of Neuroscience and Cell Biology University of Texas Medical Branch	Central sensitization is a spinal cord form of long term potentiation (LTP)	Karin High
May 20 3:00 pm MN 563	Alfred Merrill, PhD Professor and Smithgall Chair in Molecular Cell Biology Georgia Institute of Technology	Navigating the Lipid Map: New technologies and surprising findings about sphingolipid biology and disease	Mariana Nikolova-Karakashan
CANCELLED May 26	Paul L. Durham, PhD Professor Director, Center for Biomedical and Life Sciences Cell Biology, Missouri State University	CANCELLED	Karin High
June 2	Kate Moore, DNP, ACNP-BC, CEN, CCRN Assistant Professor College of Nursing University of Kentucky	Measuring the physiologic response to injury	Mike Reid

Fall 2010 MN-463, Chandler Medical Center
Wednesdays at 3:00 p.m. (unless otherwise noted)

Date	Speaker	Title	Host
September 1	Stavros Lomvardas, PhD Assistant Professor Dept. Anatomy University California San Francisco	Epigenetic silencing sets the stage for the monoallelic expression of olfactory receptor genes	Tim McClintock
September 8	Qihai (David) Gu, MD Assistant Professor Department of Physiology University of Kentucky	Bronchopulmonary C-fiber Sensory Receptors in Health and Disease	Lu-Yuan Lee
September 15	Open
September 22	Vince Kellen Chief Information Officer University of Kentucky	Why some visuals don’t work: A mental models and relational complexity account of naïve Bayesian inference.	Dave Randall
September 29	Gregory Frolenkov, PhD Assistant Professor Dept. Physiology University of Kentucky	Shaping mechanosensitivity of mammalian cochlear hair cells
October 6	Francisco Andrade, PhD Associate Professor Dept. Physiology University of Kentucky	Activity-stimulated glucose uptake in the diaphragm: the exception to the rule?
October 13	Richard A. Lang, PhD Professor and Endowed Chair Director of the Visual Systems Group University of Cincinnati College of Medicine	Mechanisms of Epithelial Morphogenesis	Gregory Frolenkov
October 20	Bret N. Smith, PhD Associate Professor Dept. Physiology University of Kentucky	Synaptic information processing in the vagal complex: Implications for metabolic regulation
October 27	Linda J. Van Eldik, PhD Director Sanders-Brown Center on Aging Professor Dept Anatomy and Neurobiology University of Kentucky	Targeting Glia Proinflammatory Cytokine Up-Regulation as a Drug Discovery Strategy for Neurodegenerative Disorders	Tom Getchell
November 3	Mariana Nikolova-Karakashian, PhD Associate Professor Dept. Physiology University of Kentucky	Lipid encounters in aging and inflammation
November 10	Walter Herzog, PhD Professor & Associated Dean Research University of Calgary	Mechanisms of muscle contraction: the three myofilament story	Karyn Esser
November 17	Dexter Speck, PhD Associate Professor Dept. Physiology University of Kentucky	Ruminations on 35 years of teaching and 55 years as a student
December 1	Michael Regnier, PhD Professor & Vice-Chair Department of Bioengineering University of Washington	Myofilament targeted approaches to improve cardiac muscle contraction	Ken Campbell
December 8	David C. Randall, PhD Professor Dept. Physiology University of Kentucky	Longitudinal Evaluation of Cardiovascular Function in Diabetic Rat
December 15	Siqi Wang Graduate Student Dept. Biomedical Engineering University of Kentucky	Dysfunction of Autonomic Regulation of Blood Pressure in Diabetic Individuals	Dave Randall

Spring 2011 MN-463, Chandler Medical Center
Wednesdays at 3:00 p.m. (unless otherwise noted)

Date	Speaker	Title	Host
January 12	Jenne Westberry, PhD Postdoctoral Fellow Department of Physiology University of Kentucky	Regulation of estrogen receptors alpha and beta in the rodent cortex
January 19	Jianguo Gu, M.B., Ph.D. Professor Department of Anesthesiology University of Cincinnati	Cold-sensing channel TRPM8 and its regulation by PIP2 and calmodulin	Suzanne Doolen
January 26	Michael Reid, PhD Professor and Chair Dept. Physiology University of Kentucky	Free Radicals, Muscle Weakness, and Fatigue
February 2	Manfred Auer, PhD Staff Scientist Lawrence Berkeley National Laboratory	Imaging biological function across scales: from macromolecules to cells, tissues and microbial communities	Gregory Frolenkov
February 9	Donald Burgess, PhD Professor Asbury College Wilmore, KY	Sympathetic Nervous System: from the RVLM to the slowly-activating K+ channel	Brian Delisle
February 16	Open
February 23	Open
March 2	Dennis Paul, PhD Associate Professor of Pharmacology LSU Health Sciences Center	Inflammation, Sodium Channels, Sodium Pumps and Diabetic Neuropathy	Brad Taylor
March 9	Erik Herzog, PhD Associate Professor Dept. Biology Washington University, St. Louis	Networked Circadian Clocks in the Brain: What Wakes You	Gretchen Wolff Karyn Esser
March 16	Alexander Rabchevsky, PhD Associate Professor Dept. Physiology University of Kentucky	Modulating the pathophysiology of autonomic dysreflexia after spinal cord injury
March 23	Bradley J. Kerr, PhD Assistant Professor Department of Anesthesiology and Pain Medicine University of Alberta	Studying neuropathic pain in Multiple Sclerosis: Finding new uses for an old animal model	Brad Taylor
March 30	Peter Vanderklish, PhD Associate Professor of Neurobiology Scripps Research Institute	Regulation of microRNA biogenesis by a stress-responsive mRNA-binding protein	Esther Dupont-Versteegden
Special Date April 8 MN 263 11am	Jean-Pierre Timmermans, PhD Univ of Antwerp Belgium	Newly emerging concepts regarding the role of the neuroepithelial body microenvironment as a complex airway receptor	Lu-Yuan Lee
Special Date April 12 MN 363 3pm	Norbert Perrimon, PhD HHMI Investigator Dept. Genetics Harvard Medical School	Proteostasis in muscle during aging	Karyn Esser
April 13	Samir Patel, PhD Department of Physiology University of Kentucky	Therapeutic interventions for spinal cord injury: Targeting mitochondrial dysfunction	Sasha Rabchevsky
April 20	Jason Groshong Kyle Rector Graduate Students Department of Physiology University of Kentucky	Inflammation and Insulin Resistance in Skeletal Myotubes Regulation of Hematopoietic Stem Cell Number by the Slit2 Encoded Intronic microRNA mir-218
April 27	Eva Bach Yi Liu Graduate Students Department of Physiology University of Kentucky	Presynaptic NMDA receptor mediated excitatory neurotransmission in the dorsal vagal compex Age and mouse strain variation in the functional capacities of highly purified hematopoietic stem cells
May 4	Mark Chapleau, PhD Professor of Physiology University of Iowa	Novel Molecular Determinants of Autonomic Regulation: Implications in Hypertension, Cardiomyopathy and Muscular Dystrophy	Lu-Yuan Lee
May 11	Howard Fields, MD, PhD Professor of Neurology and Physiology Director of the Wheeler Center for the Neurobiology of Addiction University of California, San Francisco.	Costs, Benefits and Decisions: a broader view of pain and reward	Brad Taylor
Special Date May 12 MN 463 3pm	Hiroshi Saito, PhD Department of Surgery University of Kentucky	Reduced inflammatory stress tolerance with aging
May 18	Premi Shekar Laura Haselhorst Graduate Students Department of Physiology University of Kentucky	Decreased Power Output in Failing Human Myocardium May Reflect Post-translational Modifications to Sarcomeric Proteins & JaK/STATinhibition to prevent post-traumatic epileptogenesis
May 25	Amy Wagers, PhD HHMI Early Career Scientist Associate Professor of Stem Cell and Regenerative Biology Department of Stem Cell and Regenerative Biology Harvard University	Tissue stem cells as targets of disease and mediators of regeneration	Kyle Rector Gary Van Zant
June 1	Thitinart Sithisarn Graduate Students Seminar 30min Department of Physiology University of Kentucky	TBA
July 18	John Furness, PhD Dept. Anatomy and Cell Biology University of Melbourne, Australia	Ghrelin and ghrelin receptors in autonomic control centres and possible relevance for spinal injured patients	Sasha Rabchevsky
July 20	James Heida, Ph.D. Department of Surgery Division of Neurosurgery Texas A&M University Health Science Center College of Medicine	Seizures and neuroinflammation: lessons from animal models using the developing rat”	Bret Smith

Fall 2011 MN-463, Chandler Medical Center
Wednesdays at 3:00 p.m. (unless otherwise noted)

Date	Speaker	Title	Host
08/24/2011	Stuart Campbell, Ph.D. Dept. Physiology, University of Kentucky	The Role of Myosin Regulatory Light Chain Phosphorylation in Left Ventricular Function
09/07/2011	Ahmed Abdel-Latif, M.D. Division of Cardiology, Univisersity of Kentucky	“The Underpinnings of Bone Marrow-derived Stem-/Progenitor Stem Cell Mobilization in Ischemic Heart Disease”	Jon Satin
09/14/2011	J. Timothy Lightfoot, Ph.D. FACSM RCEP CES Omar Smith Endowed Professor of Kinesiology Director Dept. of Health and Kinesiology, Texas A&M University	"The Short and Winding Trail: Is Voluntary Activity Really Voluntary?"	Mike Reid
09/19/2011, MN263, 3:00 pm	John C. Gensel, Ph.D. Post Doctoral Research Fellow, The Ohio State University College of Medicine	"Reprogramming macrophages to promote repair after spinal cord injury"	SCoBIRC/PGY faculty candidate
09/21/2011	Hazel Szeto, M.D., Ph.D. Dept. Pharmacology, Cornell University	“Novel Therapies Targeting the Mitochondrial Electron Transport Chain”	Mike Reid
09/28/2011	Thomas Clemens, Ph.D. Professor, Director Center for Musculoskeletal Research, The Johns Hopkins School of Medicine	"The Skeleton as a Regulator of Glucose Metabolism"	Karyn Esser
10/05/2011	Steve Muza, Ph.D. U.S. Army Research Institute of Environmental Medicine	"Altitude Acclimatization: Effects of Hypobaric versus Normobaric Hypoxia"	Lu-Yuan Lee
10/12/2011	James Tidball, Ph.D. Professor, Department of Integrative Biology and Physiology, UCLA	Mechanisms of Muscle Injury, Repair and Regenration	Esther Dupont-Versteegden
10/19/2011	Babak Bazrgari, Ph.D. Assistant Professor Center for Biomedical Engineering, Univ. Kentucky	“Spine biomechanics and low back pain”
10/21/2011, MN463, 11:00 am	Dustin Armstrong, Ph.D. Vice President, 4s3 Bioscience	"Target & Deliver: Novel Biotherapeutics for Mutational Muscular Diseases – A Startup Perspective"	Postdoctoral fellows
10/26/2011	Anthony Ricci, Ph.D. Professor, Department of Otolaryngology, Department of Cellular and Molecular Physiology, Stanford University	"Exploring the pore properties of the hair cell mechanotransduction channel."	Gregory Frolenkov
11/02/2011	John J. McCarthy, Ph.D. Research Assistant Professor, Dept. Physiology, Univ. Kentucky	“Robust hypertrophy in satellite cell depleted skeletal muscle”
11/09/2011	Christian Hong, Ph.D. Assistant Professor, Dept. Molecular and Cellular Physiology, Univ. Cincinnati	"Interplay between circadian rhythms and cell cycle in Neurospora crassa"	Karyn Esser
11/23/2011, MN363, 2:00 pm	Zachary Fulkerson Dept. Physiology, Univ. Kentucky	"Lysophosphatidic Acid Production and Signaling in Platelets", Ph.D. defense seminar
11/30/2011	Paula Heron, Ph.D. Dept. Physiology, University of Kentucky	"Olfactory Sensory Neuron Axon Growth and Targeting"
12/07/2011	Jeffrey Holt, Ph.D. Associate Professor, Childrens Hospital Boston, Harvard Medical School	"The Molecules and Mechanisms of Mechanotransduction in the Mouse Inner Ear"	Gregory Frolenkov
12/14/2011	A. Catalina Vélez-Ortega Shawn A. Stasko Graduate Students Seminar, 2x30min, Department of Physiology, University of Kentucky	"Do TRPA1-mediated responses in supporting cells protect the cochlea from noise damage?" "Reactive Oxygen Species Mediate TNF-induced Diaphragm Dysfunction"

Spring 2012 MN-463, Chandler Medical Center
Wednesdays at 3:00 p.m. (unless otherwise noted)

Date	Speaker	Title	Host
01/04/2012	Craig Vander Kooi, Ph.D. Assistant Professor Department of Cellular and Molecular Biochemistry, University of Kentucky	“Structure and Function of Neuropilin in Angiogenesis”
01/11/2012	Gabor J. Tigyi, M.D., Ph.D. Chairman and Professor of Physiology, University of Tennessee	"Chemical Biology of Autotaxin Inhibition"	Susan Smyth
01/18/2012	Michael Hughes, Ph.D. Department of Cellular and Molecular Physiology, Yale School of Medicine	"Tempo and harmonics; orchestrating transcriptional rhythms in mammals and flies"	Karyn Esser
02/08/2012	Michael Reid, Ph.D. Professor, Dept. Physiology, Univ. Kentucky	"Regulation of Cell Size by nSMase3, A Novel Muscle-Specific Protein"
02/15/2012	Brandon Fornwalt, M.D., Ph.D. Assistant Professor, Dept of Pediatrics, Univ. Kentucky	"Resynchronizing the Failing Heart: Lessons Learned from Non-Responders and Dyssynchronous Literature"
02/22/2012	James K. Hartsfield, Jr., DMD, PhD Professor & Chair, Orthodontics, College of Dentistry, University of Kentucky	"Genetic Factors Associated With Resorption of Tooth Roots During Orthodontic Treatment"	Steve Estus
02/29/2012	David Brown, Ph.D. Senior Research Scientist Center for Biomedical Engineering, University of Kentucky	“I/f and Other Four Letter Words”	Dave Randall
03/07/2012, MN363, 4:00 pm	Bret H. Goodpaster, Ph.D. Associate Professor of Medicine, University of Pittsburgh	"Does skeletal muscle fat accumulation play a role in the loss of function in aging?"	Charlotte Peterson
03/14/2012	Daniel Bartos Ryan Griggs Graduate Students Seminar, 2x30min, Department of Physiology, University of Kentucky	“The Contribution of Kv7.1 to the Cardiac Action Potential and Arrhythmogenesis” & “Spinal Mechanisms of Pain in Diabetic Neuropathy”
03/21/2012	Holly VanRemmen, Ph.D. Professor University of Texas Health Sciences Center, San Antonio	"The Role of Oxidative Stress in Age-Related Neuromuscular Degeneration: The Importance of Staying Connected"	Charlotte Peterson
03/28/2012	Fadi Xu, M.D. Scientist, Lovelace Respiratory Research Institute	“Depression of Ventilatory Responses to Hypercapnia and Hypoxia: Central Mechanisms of Opioids”	Lu-Yuan Lee
04/04/2012	Gregory Corder Ishita Parikh Graduate Students Seminar, 2x30min, Department of Physiology, University of Kentucky	“Pain allostasis is regulated by constitutive opioid receptor signaling after injury” ” & "Understanding Alzheimers Disease: A Role for PICALM Splice Variants?”
04/11/2012	David C. Randall, Ph.D. Professor Dept. Physiology, University of Kentucky	“Alternative (and some heretical) notions regarding regulation of arterial blood pressure and the etiology of hypertension”
04/18/2012	Jeffrey G. Tasker, Ph.D. Professor, Department of Cell and Molecular Biology, Tulane University	"The role of glial-neuronal interactions in hypothalamic neuroendocrine cell signaling"	Bret Smith
04/25/2012	Rohan Kaushal Jenny Lutshumba Graduate Students Seminar, 2x30min, Department of Physiology, University of Kentucky	“ Knockdown of Locus Coeruleus Noradrenergic Neurons Alleviates Chronic Orofacial Pain” & "Bmal1 Deletion from Smooth Muscle Cells Protects from Aortic Aneurysm"
05/02/2012	Joseph C. Ruiz, Ph.D. Vice President, Research, Transposagen Biopharmaceuticals, Inc., Lexington, KY	"New technologies for site-specific and transposon-mediated engineering of the mammalian genome"	Jon Satin
05/23/2012	Mikhail Nemenov, Ph.D. Chief Scientist, Lasmed LLC, Mountain View, CA; Consulting Professor, Department of Anesthesia, Stanford University	"Particularities of heat stimulating of cells and small nerve fibers by infrared diode laser"	Brad Taylor

Fall 2012 MN-463, Chandler Medical Center
Wednesdays at 3:00 p.m. (unless otherwise noted)

Date	Speaker	Title	Host
08/29/2012	Lin Yang, Ph.D. Assistant Professor, Dept of Biostatistics, and Dept. of Computer Science, University of Kentucky	"Automatic image analysis for muscle"	Karyn Esser
09/12/2012		Open
09/19/2012	Brian Kennedy, PhD CEO & President, Buck Institute for research on Aging	“Modulating Healthspan – Moving From Genes to Intervention Strategies”	Mariana Nikolova-Karakashian
09/26/2012	Pedro L. Vera, Ph.D. Associate Chief of Staff/R&D Lexington VAMC	“Macrophage Migration Inhibitory Factor: Role in Pelvic Viscera Inflammation and Cancer”
10/01/2012, MN363, 10:00 am	Jose F. Abisambra, Ph.D., Univ. South Florida College of Medicine, Dept. Molecular Medicine	“Chaperoning Tau: Discovery of Therapeutic Targets for Tauopathies”	Sanders-Brown Center on Aging, Faculty candidate
10/03/2012	Jian-Ping Jin, Ph.D. Professor and Chairman, Department of Physiology Wayne State University School of Medicine	“Regulation and Function of Troponin”	Karyn Esser
10/04/2012, 11:00-12:00, MN463, notice special date/time	Ming Gong, Ph.D. Associate Professor, Department of Physiology, University of Kentucky	"Hypertension and Disrupted Blood Pressure Circadian Rhythm in Diabetes"
10/17/2012	Charles Miller, III, PhD Associate Dean for Research, Professor and Chair, Department of Biomedical Sciences, Texas Tech University Health Sciences Center	"The University Research Mission – Clinical Research and Beyond"	Mike Reid
10/24/2012	Jennifer Van Eyk, Ph.D. Associate Professor of Medicine Johns Hopkins University	“Integrating Proteomics: Tackling the Unknowns in Heart Disease”	Ken Campbell
10/31/2012	Alexander Rabchevsky, Ph.D. Associate Professor, Department of Physiology, University of Kentucky	“Novel targets for spinal cord injury therapeutics: bioenergetic and autonomic dysfunctions”
11/07/2012	Min Zhuo, Ph.D. Professor of Physiology, EJLB-CIHR Michael Smith Chair in Neurosciences and Mental Health University of Toronto	"Gentic and synaptic investigations of cortical mechanisms for chronic pain"	Brad Taylor
11/14/2012	Elisabeth Barton, Ph.D. Associate Professor, Department of Anatomy & Cell Biology, University of Pennsylvania	“The Pros and Cons of Sugar-free IGF-I for Muscle”	Mike Reid
12/05/2012	Chris A. Flask, Ph.D. Assistant Professor of Radiology, Biomedical Engineering, and Pediatrics, Case Western Reserve University	Cancelled	Brandon Fornwalt

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Physiology

Spring 2008 MN-463, Chandler Medical Center Wednesdays at 3:00 p.m. (unless otherwise noted)

Fall 2008 MN-463, Chandler Medical Center Wednesdays at 3:00 p.m. (unless otherwise noted)

Spring 2009 MN-263, Chandler Medical Center Wednesdays at 3:00 p.m. (unless otherwise noted)

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Spring 2010 MN-463, Chandler Medical Center Wednesdays at 3:00 p.m. (unless otherwise noted)

Fall 2010 MN-463, Chandler Medical Center Wednesdays at 3:00 p.m. (unless otherwise noted)

Spring 2011 MN-463, Chandler Medical Center Wednesdays at 3:00 p.m. (unless otherwise noted)

Fall 2011 MN-463, Chandler Medical Center Wednesdays at 3:00 p.m. (unless otherwise noted)

Spring 2012 MN-463, Chandler Medical Center Wednesdays at 3:00 p.m. (unless otherwise noted)

Fall 2012 MN-463, Chandler Medical Center Wednesdays at 3:00 p.m. (unless otherwise noted)