PAMELA A. STEIN, D.M.D

UK Department of Anatomy and Neurobiology

Faculty Research

PAMELA A. STEIN, D.M.D
D.M.D, University of Kentucky (1990)
Assistant Professor, Special Titles Series

Research Interests: Investigating the potential role of oral disease as a risk factor in the development of dementia

In the last twenty years many studies have been conducted to investigate the role of oral disease, specifically periodontal disease, on several systemic diseases, including stroke, coronary heart disease, and pre-term birth. Research suggests that the chronic systemic inflammation associated with gum disease increases the risk for these diseases. Dr. Stein conducts research with the Sander’s Brown Center on Aging and the Nun Study to investigate oral disease as a potential risk factor for dementia.

In addition, she is involved in scholarly work in creating software and texts relating basic science and clinical dentistry, particularly in the area of local anesthesia and head and neck anatomy.

Representative Publications

Stein PS, Desrosiers M, Donegan SJ, Kryscio R, Yepes J. Tooth loss, dementia, and neuropathology in the Nun Study. Cover Story. Journal of the American Dental Association October 2007, 38:1314-22.

Stein P, Scheff S, Dawson DR. Alzheimer’s disease and periodontal disease: mechanisms underlying a potential bidirectional relationship. Grand Rounds in Oral-Systemic Medicine September 2006, 1:14-24.

Stein P, Brueckner JK, Matthew Milliner. Sensory innervation of mandibular teeth by the nerve to the mylohyoid: Implications in local anesthesia. Clinical Anatomy October 2007, 20:591-595.

Stein P, Brueckner JK, Mink JR. The Anatomy of Pediatric Local Anesthesia, Journal of Pediatric Dental Care May 2006, 12:29-31.

e-mail: pam.stein @uky.edu
phone: (859)323-5591
fax: (859)323-5946