John Williams, PhD

Associate Professor of Medicine

University of Kentucky
Albert B. Chandler Medical Center
800 Rose Street, Room MN-564
Lexington, KY  40536-0298

Phone:  (859) 323-5049
Fax :  (859) 323-0232

jpwill2@uky.edu

Curriculum Vitae

Selected Publications: 

Larsen KI, Wang W, and Williams JP. Glucose stimulated calcium dependent signaling in osteoclasts. (in preparation).

Ponomereva L, Wang W, and Williams JP. Osteoclast-secreted hemokine, mim-1, stimulates osteoblast differentiation and matrix mineralization. (submitted Am. J. Physiol.).

Langub MC, Monier-Faugere M-C, Wang G, Williams JP, Koszewski NJ, and Malluche HM. Administration of PTH-(7-84) antagonizes the effects of PTH-(1-84) on bone in rats with moderate renal failure. Endocrinology 2003; 144:1135-1138.

Williams JP, Thames AM III, McKenna MA, and McDonald JM. Antagonists of calmodulin and Protein Kinase C Inhibit Bone Resorption and Acid Transport by different mechanisms. (In Press, Calcif Tes Int).

Williams JP, McKenna MA, Thames AM III, and McDonald JM. Effects of Cyclosporin on osteoclast activity: Inhibition of calcineurin activity with minimal effects on bone resorption and acid transport activity. J. Bone and Miner. Res. 2003; 18:451-457.

Larsen KI, Falany ML, Ponomereva L, Wang W, and Williams JP. Glucose dependent regulation of osteoclast H⁺-ATPase expression: Potential role of p38 MAP kinase. J. Cell. Biochem. 2002; 87: 75-84.

Falany ML, Thames AM III, McDonald JM, Blair HC, McKenna MA, Moore RE, Young MK, and Williams JP. Osteoclasts secrete the chemotactic cytokine mim-1. Biochem. Biophys. Res. Commun. 2001; 281: 180-185.