Center for Muscle Biology

Adult Skeletal Muscle Symposium: Clinical Problems, Molecular Targets

Oct 30-31, 2008
The Lexington Downtown Hotel & Conference Center, Lexington, Kentucky
Organizers: Susan Kandarian and Karyn Esser

PLEASE NOTE: We will be running a live blog/wiki page throughout the meeting to allow for active participation of all attendees. Please bring your wireless device to participate.

Thursday October 30

• 8:30-8:40 a.m. K. Esser, Ph.D. University of Kentucky
  Welcome and Introduction
• 8:45-9:15 a.m. Roger Fielding, Ph.D. Tufts University
  Muscle power is a critical determinant of function in older adults
• 9:20-9-50 a.m. Leigh Ann Callahan, M.D. University of Kentucky
  Acquired weakness in critically ill patients
• 9:50-10:10 a.m. Break (coffee)

Factors/biomarkers of human skeletal muscle health

• 10:15-10:45 a.m. Bob Fitts, Ph.D Marquette University
  Structure-function relationships in atrophied skeletal muscle fibers
• 10:50-11:20 a.m. Melinda Sheffield Moore, Ph.D. University of Texas Medical Branch
  Androgens and the control of skeletal muscle protein synthesis in humans
• 11:25-11:55 a.m. Jane Kent Braun, Ph.D. University of Massachusetts - Amherst
  Impact of old age on human skeletal muscle bioenergetics in vivo
• 12:00-12:40 p.m.Speaker Panel Discussion
  Moderator: Dr. Michael Reid
  Moderator: Dr. Charlotte Peterson
• 12:45-1:45 p.m. Lunch

Molecular regulation of anabolic pathways in skeletal muscle

• 2:00-2:30 p.m. Scot Kimball, Ph.D. Penn State University College of Medicine
  The role of mTORC1 in skeletal muscle protein anabolism
• 2:35-3:05 p.m. Marta Fiorotto, Ph.D. Baylor College of Medicine
  IGF1 regulation of protein synthesis in skeletal muscle
• 3:10-3:40 p.m. Troy Hornberger, Ph.D. University of Wisconsin, Madison
  Mechanotransduction and the regulation of skeletal muscle mass
• 3:45-4:15 p.m. Speaker Panel Discussion
  Moderator: Dr. Karyn Esser
• 4:15-5:00 p.m. Break
• 5:00-5:30 p.m. Reception
• 5:30-7:30 p.m. Poster Session

Friday October 31

• 8:30-9:00 a.m. Stewart Lecker, M.D., Ph.D., Beth Israel Deaconess Medical Center
  The role of atrogin-1 in muscle atrophy and damage
• 9:05-10:35 a.m. Gerald Supinski, M.D. University of Kentucky
  The role of calpain and caspase in force loss and protein breakdown
• 10:40-11:10 a.m. Denis Guttridge, Ph.D. Ohio State University
  Mechanisms of muscle wasting in cachexia
• 11:15-11:45 a.m. Speaker Panel Discussion
  Moderator: Dr Susan Kandarian
  Moderator: Dr. Robert Jackman
• Noon: Departure

Registration will be free but space is limited. For questions please email Karyn Esser at karyn.esser@uky.edu

Sponsored by: Eli Lilly and Company
Pfizer Incorporated
University of Kentucky Center for Muscle Biology
UK Center for Clinical and Translational Science

Endorsed by the American Physiological Society