Thomas Roszman, Ph.D.

Selliah, N., W.H. Brooks and T.L. Roszman. Proteolytic cleavage of a-actinin by calpain in T-cells stimulated with anti-CD3 monoclonal antibody. J. Immunol. 156:3215-3221, 1996

Morford, L.A., Boghaert, E.R., Brooks, W.H. and Roszman, T.L. Insulin-like growth factors (IGF) enhance three-dimensional (3D) growth of human glioblastomas. Cancer Letters 115:81-90, 1997

Morford L.A., Elliott L.H., Carlson S.L., Brooks W.H., and Roszman T.L. T-cell receptor-mediated signaling is defective in T-cells obtained from patients with Primary Intracranial Tumors. J. Immunol. 159:4415-4425, 1997

Rock, M., W.H. Brooks and T.L. Roszman. Signaling of T-cells induces activation of calpain and the subsequent proleolytic cleavage of PTP-1B which binds to p130cas J. Biol.Chem. 272:33377-33383, 1997

Zou, J-P., L.A. Morford, C. Chougnet, A.R. Dix, A.G. Brooks, N. Torres, J.D. Shuman, J.E. Coligan, W.H. Brooks, T.L. Roszman and G.M. Shearer. Human glioma-induced immunosuppression involves soluble factor(s) that alters monocyte cytokine profile and surface markers. J. Immunol. 162:4882-4892, 1999

Dix, A.R., Brooks, W.H., Roszman, T.L. and Morford, L.A. Immune defects observed in patients with primary malignant brain tumors. J.Neuroimmunol. 100(1-2):216-32, 1999

Morford, L.A., Dix, A.R., Brooks, W.H., and Roszman,T.L. Apoptotic elimination of peripheral T lymphocytes in patients with primary intracranial tumors. J.Neurosurg, 91(6):935-45, 1999