Vivek Rangnekar, Ph.D.

N. El-Guendy, Y. Zhao, S. Gurumurthy, R. Burikhanov, and V. M. Rangnekar (2003) Identification of a unique core domain of Par-4 sufficient for selective apoptosis-induction in cancer cells. Mol. Cell. Biol. 23: 5516-5525. [Abstract]

J. Butler and V. M. Rangnekar (2003) Par-4 for molecular therapy of prostate cancer (review). Current Drug Targets. 4: 223-230

K. M. Vasudevan,S. Gurumurthy, and V. M. Rangnekar. (2004) Suppression of PTEN Expression by NF-kappaB Prevents Apoptosis. Mol. Cell. Biol. 24: 1007–1021 [PDF]

N. El-Guendy and V. M. Rangnekar. (2003) Apoptosis by Par-4 in cancer and neurodegenerative diseases. (review) Experimental Cell Research 283: 51-66 [Abstract]

Gurumurthy S, Goswami A, Vasudevan KM, Rangnekar VM. (2005) Phosphorylation of Par-4 by protein kinase A is critical for apoptosis. Mol Cell Biol. 25:1146-61 [Abstract]

A. Goswami, R. Burikhanov, A. de Thonel, N. Fujita, M. Goswami, Y. Zhao, J. E. Eriksson, T. Tsuruo, and V. M. Rangnekar (2005) Binding and phosphorylation of Par-4 by Akt is essential for cancer cell survival. Molecular Cell 20, 33–44. [Article]

Suppression of PTEN Expression Is Essential for Antiapoptosis and Cellular Transformation by Oncogenic Ras
Krishna Murthi Vasudevan, Ravshan Burikhanov, Anindya Goswami, and Vivek M. Rangnekar
Cancer Res 2007 67: 10343-10350. doi: 10.1158/0008-5472.CAN-07-1827 [PDF]

Cancer Resistance in Transgenic Mice Expressing the SAC Module of Par-4
Yanming Zhao, Ravshan Burikhanov, Shirley Qiu, Subodh M. Lele, C. Darrell Jennings, Subbarao Bondada, Brett Spear, and Vivek M. Rangnekar
Cancer Res 2007 67: 9276-9285. doi: 10.1158/0008-5472.CAN-07-2124 [PDF]