Guangxiang Luo, MD, MPH

Kyung-Soo Chang, Zhaohui Cai, Chen Zhang, Ganes C. Sen, Bryan R. G. Williams, and Guangxiang Luo* (2006) Replication of Hepatitis C Virus (HCV) RNA in Mouse Embryonic Fibroblasts: Protein Kinase R (PKR)-Dependent and PKRIndependent Mechanisms for Controlling HCV RNA Replication and Mediating Interferon Activities. Journal of Virology 80:7364-7374. [PDF]

Chang, KS, and G. Luo. (2006) The polypyrimidine tract-binding protein (PTB) is required for efficient replication of hepatitis C virus (HCV) RNA. Virus Research 115:1-8. [PDF]

Zhaohui Cai, MinKyung Yi, Chen Zhang, and Guangxiang Luo. (2005) Mutagenesis Analysis of the rGTP-Specific Binding Site of Hepatitis C Virus RNA-Dependent RNA Polymerase. Journal of Virology 79:11607-11617. [PDF]

Zhaohui Cai, Chen Zhang, Kyung-Soo Chang, Jieyun Jiang, Byung-Chul Ahn, Takaji Wakita, T. Jake Liang, and Guangxiang Luo (2005) Robust Production of Infectious Hepatitis C Virus (HCV) from Stably HCV cDNA-Transfected Human Hepatoma Cells. Journal of Virology 79:13963-13973. [PDF]

Theo Heller†, Satoru Saito†, Jonathan Auerbach, Tarice Williams, Tzivia Rachel Moreen, Allison Jazwinski, Brian Cruz, Neha Jeurkar, Ronda Sapp, Guangxiang Luo, and T. Jake Liang. (2005) An in vitro model of hepatitis C virion production. PNAS 102:2579-1583. [PDF]

Chen Zhang, Zhaohui Cai, Young-Chan Kim, Ranjith Kumar, Fenghua Yuan, Pei-Yong Shi, Cheng Kao, and Guangxiang Luo. (2005) Stimulation of Hepatitis C Virus (HCV) Nonstructural Protein 3 (NS3) Helicase Activity by the NS3 Protease Domain and by HCV RNA-Dependent RNA Polymerase. Journal of Virology 79:8687-8697. [PDF]

Luo, G. (2004) Molecular Virology of Hepatitis C Virus. Hepatitis Prevention and Treatment. Birkhauser Verlah, Switzerland. P67-85.

Cai, Z.; T. J. Liang, and G. Luo (2004) Effects of mutations of the initiation nucleotides on hepatitis C virus RNA replication in cell culture. Journal of Virology 78:3633-3643. PDF

El-Hage, N. and G. Luo (2003) Replication of hepatitis C virus RNA occurs in the membrane-bound replication complex containing the nonstructural viral proteins and viral RNA. J. Gen. Virol. 84:2761-2769. PDF

Luo, G., S. Xin, and Z.-H. Cai (2003) Role of the 5’-proximal stem-loop structure of the 5’ untranslated region in replication and translation of hepatitis C virus RNA. Journal of Virology 77:3312-3318. PDF

Luo, G., R. Hamatake, D.M. Mathis, J. Racela, K. L. Rigat, J. Lemm, and R. Colonno. (2000) De Novo Initiation of RNA Synthesis by the RNA Dependent RNA Polymerase (NS5B) of the hepatitis C Virus. Journal of Virology. 74(2) 851-863. PDF

Luo, G. (1999) Cellular proteins bind to the poly(U) tract of the 3’ UTR of hepatitis C virus RNA genome. Virology 256(1):105-118. PDF