Skeletal Muscle Structure and Function

COURSE NUMBER: PGY 825 001

COURSE TITLE: Skeletal Muscle Structure and Function

COURSE DIRECTOR: Karyn Esser, Ph.D.
MS-567, UKMC
Phone: 323-8107
karyn.esser@uky.edu

OBJECTIVES: In almost all chronic diseases studied (e.g. cancer, diabetes, kidney disease, arthritis) there is associated and profound weakness. Historically it was believed that the diaphragm and peripheral muscle weakness was due to the inactivity of the patient. However, recent studies have demonstrated that the muscle becomes pathological resulting in the significant weakness seen in patients with these diseases. In some cases there is some evidence that the patient exhibits significant muscle weakness prior to displaying of disease symptoms (joint changes in osteoarthritis) so understanding sites of muscle weakness could potentially be informative for clinical diagnosis. The goals of this class are to discuss the major issues of skeletal muscle structure and function and to review current literature in chronic diseases and muscle health.

CONTENT & METHOD OF TEACHING: This is a seminar class, not a lecture class, so the grade will come primarily from class participation and a presentation.

CREDIT HOURS: 1

Time and location: TBA

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