E-mail: Martin E. Evans, M.D. Phone: 859-381-5960 Fax: 859-323-8926 Office: VAMC- B 415C

Martin E. Evans, M.D.
Professor of Medicine, Division of Infectious Diseases
Fellowship Director, Division of Infectious Diseases
Chair, Task Force for Bioterrorism Preparedness

Medical School
The University of Virginia School of Medicine

Residency
Wilford Hall United States Air Force Medical Center, San Antonio

Fellowships
Infectious Diseases, Vanderbilt University School of Medicine
Infectious Diseases and Pathology, Vanderbilt University School of Medicine

Board Certifications
American Board of Internal Medicine
American Board of Internal Medicine, Subspecialty of Infectious Diseases
American Board of Pathology, Special Competence in Medical Microbiology

Clinical Interests
Hospital infection control
Antibiotic Resistance

Research Interest
Pharmacokinetics, pharmocodynamics, and fluoroquinolone resistance in Staphylococcus aureus

Current Grant Activity

2003/2004 Publications

Baker, B., Evans, M.E., deCastro, F., and Schosser, R.  leprosy in a Mexican immigrant.  J KY Med Assoc 2003;101:419-424.

Rapp, R.P., Evans, M.E., Martin, C., Ofotokun, I., Empey, K.L., and Armistead, J.A.  Drug Costs and bacterial susceptibility after implementing a single-fluoroquinolone use policy at a university hospital.  Curr Med Res Opinion 2004;20:469-476.

Greenberg, R.N., Schosser, R.H., Plummer, E.A., Roberts, S.E., Caldwell, M.A., Hargis, D.L., Rudy, D.W., Evans, M.E. and Hopkins, R.J.  Urticaria, exanthems, and other benign dermatologic reactions to smallpox vaccintaion in adults.  Clin Infect Dis  2004; 38:958:965.

Campion, J.J, McNamara, P.J., and Evans, M.E.  Evolution of ciprofloxacin-resistant Staphylococcus aureus in vivo pharmacokinetic environments.  Antimicrob Agents Chemother 2004;48:4733-4744.

Evans, M.E.  Gene Therapy and Infection Control (Chapter 19).  In Wenzel, R.P. (Ed.)  Prevention and Control of Nosocomial Infections, 4th Edition, Lippincott Williams & Wilkins, Baltimroe, MD, 2003:262-278.

Weber, D.J., Evans, M.E., Rutala, W.A.  Infection Control in Gene Therpay (Chapter 72).  In Mayhall, C.G. (Ed.) Hospital Epidemiology and Infection Control, 3rd Edition, Lippincott Williams, & Wilkins, Baltimore, MD, 2004:1279-1288.

2002/2003 Publications
Empey, K.M., Rapp, R.P., Evans, M.E. The effect of an antimicrobial formulary change on resistance patterns. Pharmacother 2002;22:81-87.

Rapp, R.P., Ribes, J., Overman, S., Darkow, T., Evans, M.E. A decade of antimicrobial susceptibilities at the University of Kentucky hospital. Ann Pharmacother 2002;36:596-604.

Evans, M.E. and Lesnaw, J.A.  Infection control for gene therapy: a busy physician’s primer. Clin Infect Dis 2002;35:597-605.

Evans, M.E. Selection of oxacillin-resistance in oxacillin-sensitive Staphylococcus aureus by exposure to ciprofloxacin but not piperacillin/tazobactam. Eur J Clin Microbiol Infect Dis 2002;21:621-623.

Ridings, H., Evans, M.E.  Understanding the threat of smallpox.  J Am Acad Physician Assist 2002;15:41-46.

Rapp, R.P., and Evans, M.E. The effect of hospital antimicrobial use alteration on resistance in gram-negative bacteria: a review.  Ochsner Clinic Reports on Serious Hospital Infections 2002;14;1-8.

Baker, B., Evans, M., deCastro, F., and Schosser, R. Leprosy in a Mexican immigrant. J Ky Med Assoc 2003;101:419-424.

Evans, M.E. Gene Therapy and Infection Control (Chapter 19).  In Wenzel, R. P. (Ed.) Prevention and Control of Nosocomial Infections, 4th Edition, Lippincott Williams & Wilkins, Baltimore, MD, 2003:262-278.

2003/2004 Abstracts

Martin, C.A., Berry, S.E., and Evans, M.E.  Improvement in the timing of perioperative antimicrobial prophylaxis when administered upon induction of anesthesia.  Interscience Conference on Antimicrobial Agents and Chemotherpay (ICAAC), September14-17, 2003, Chicago.

Campion, J.J, McNamara, P.J., and Evans, M.E.  Selection of fluoroquinolone-resistant methicillin resistant Staphylococcus aureus:  comparison of garenoxacin, gatifloxacin, and ciprofloaxacin.  Interscience Conference on Antimicirobial Agents and Chemotherapy (ICAAC), September 14-17, 2003, Chicago.

Voils, S. A., Lane, M.T., Evans, M.E., Rapp, R.P.  Non-infectious uses of antibiotics:  Efficacious or selecting resistance.  AM Soc Health Systems Pharmacists mid-year meeting, New Orleans, December, 2003.

Campion, J.J., Evans, M.E.  Pharmacodynamic modeling of the selection of gr1A mutants of methicillin-resistant Staphylococcus aureus by garenoxacin, gatifloxacin, and ciprofloxacin.  11th International Symposium on Staphylococci & Staphylococcal Infections, Charleston, N.C., October  24-27,. 2004.

Campion, J.J, Evans, M.E.  Pharmacodynamic modeling of levofloxacin resistance in Staphylococcus aureus populations exposed to simulated in vitro pharmacokinetic profiles:  comparison with ciprofloxacin.  11th International symposium on Staphylococci & Staphylococcal Infections, Charleston, N.C., October 24-27, 2004.

2002/2003 Abstracts
Ofotokun, I., Rapp, R.P., Empey, K., Martin, C., Armitstead, J., Pomeroy, C., Evans, M.E. Results of a four-year effort to control the use of antimicrobial agents at a university-affiliated hospital. Infectious Diseases Society of America (IDSA) Annual Meeting, Chicago, October , 2002.

Campion, J.J., Evans, M. E., McNamara, P. J. Pharmacodynamic modeling of ciprofloxacin resistance in Staphylococcus aureus. American Association of Pharmaceutical Scientists Annual Meeting and Exposition, Toronto, Canada, November, 2002.

Chung, P., Evans, M. E., Moscow, J., McNamara, P. J. Development of a molecular beacon-based real-time PCR assay to detect and quantify the grlA gene of Staphylococcus aureus. American Association of Pharmaceutical Scientists Annual Meeting and Exposition, Toronto, Canada, November, 2002.

Martin, C.A., Berry, S.E., and Evans, M.E. Improvement in the timing of perioperative antimicrobial prophylaxis when administered upon induction of anesthesia. Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), September 14-17, 2003, Chicago.

Campion, J. J, McNamara, P. J., and Evans, M.E. Selection of fluoroquinolone-resistant methicillin resistant Staphylococcus aureus: comparison of garenoxacin, gatifloxacin, and ciprofloxacin. Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), September 14-17, 2003, Chicago.