Dr. Dennis Karounos

Curriculum Vitae

Office Address:
Department of Internal Medicine
800 Rose Street
Room 520
Lexington, KY
40536-0298

Lab Address:
Veterans Administration Hospital
Room C312
Clinical Addition
Lexington, KY 40507

Office:
(859) 323-5821
Lab:
(859) 233-4511x4289

E-Mail: dkaroun@uky.edu

Clinical Interests

Intensive therapy of type 1 and type 2 diabetes, insulin pump therapy, continuous glucose sensor monitoring, insulinomas, and pancreas transplantation.

Research Interests

Immunology of type 1 diabetes, role of rubella virus in the pathogeneisis of type 1 diabetes, prevention of diabetes with insulin or insulin analogs, intensive control of type 2 diabetes and macrovascular complications of diabetes.

Current Projects

Use of Insulin Analogs to Prevent Type 1 Diabetes in Mice

The Efficacy  of Heat Shock Peptide 277 in individuals with Latent Autoimmune Diabetes of Adults (LADA)

Veterans Administration Cooperative Study (VACS #465):  Glycemic Control and Complications in Diabetes Mellitus Type 2 VADT (VA Diabetes Trial), Co-investigator, Lexington, KY

Research

1. Veterans Affairs Administration: Merit Review: Optimizing Insulin Therapy for the Prevention of Type I Diabetes. PI:  D.G. Karounos.  Start date: 4/1/98 to 3/31/2002. 
   
   
   
2. National Institutes of Health  1R01 NS39774-01A1  
   PI: David C. Randall 
   Sympathetic Function in Diabetes  Dennis G. Karounos, M.D.
   Role in project: Co-investigator  Effort: 15% start dates: 11/01/00 to 10/31/03:  3 yrs:

3. Veterans Administration Diabetes Cooperative Study #465:  Title: Glycemic Control and Complications in Diabetes Mellitus Type 2.  PI:  Dennis G. Karounos
   Role in project: Principal investigator Start Dates: 07/12/00-6/31/07. 

4. D.G. Karounos, PI VA Merit Review: Prevention of type 1 Diabetes with Insulin Analogs: Preclinical studies, December 2001, start 4/1/2002-3/31/2006 4 yrs :  .