AAA PPG Mouse Core
Debra L. Rateri, B.S.
The purpose of this Core is
to provide a central location for the supply of mice and
services related to mouse care, maintenance, genotyping,
and measurement. Specifically this Core will offer the
Bone marrow transplantation: (PDF)
Systolic blood pressure measurement: (PDF)
Alzet pump implantation: (PDF)
DNA harvest: Mice at 3 weeks of age will be ear marked, numbered, and tail clipped. Genomic DNA will be isolated using Qiagens DNeasy Tissue Kits. The isolated DNA will be given to each Investigators laboratory for PCR genotype screening.
In vivo ultrasound: (PDF)
|1. Daugherty, A. , M. W. Manning, and L.A.
Cassis. (2000) Angiotensin II promotes atherosclerotic
lesions and aneurysms in apolipoprotein E deficient
mice. Journal of Clinical Investigation. 105:1605-1612.
2. Daugherty, A. and L.A. Cassis (2002) Mechanisms of arterial aneurysm formation. Current Atherosclerosis Reports. 4:222-227.
3. Daugherty, A. and S.C. Whitman. (2003) Use of the mouse for studying atherosclerosis. The Transgenic Mouse: Methods and Protocols. pg 293-309. Ed. M. Hofker and J. van Deursen. Humana Press, Totowa, New Jersey.
4. Daugherty, A. and D.L. Rateri. (2005) Development of experimental designs for atherosclerosis studies in mice. Methods. 36: 129-138.
5. Daugherty, A. and D.L. Rateri (2006) Hyperlipidemia-induced atherosclerosis. A Handbook of Mouse Models for Cardiovascular Diseases. pg. 53-66. Ed Q. Xu, Wiley, London.
6. Barisione, C, D.L. Howatt, J. Moorleghen, D.L. Rateri, and A. Daugherty. (2006) Rapid dilation of the abdominal aorta during infusion of angiotensin II detected noninvasively by high frequency ultrasound. Journal of Vascular Surgery. In press.
7. Wang, Y.X., L.A. Cassis, and A. Daugherty. (2006). Angiotensin II-induced abdominal aortic aneurysms. A Handbook of Mouse Models for Cardiovascular Diseases. pg 125-146. Ed Q. Xu, Wiley, London.
8. Lu, H., D.L. Rateri, and A. Daugherty (2007) Immunostaining of mouse atherosclerotic lesions. Vascular Biology Protocols. Eds. Sreejayan and J. Ren. Human Press, Totowa, New Jersey. In press.