AAA PPG Core C
Hong Lu, Ph.D.
Deborah Howatt, B.S.
This Core will facilitate the measurements and
characterization of vascular pathology and of plasma
parameters that are critical to the interpretation of
experimental studies. The quantification of these
vascular pathologies requires trained personnel.
Therefore, having experienced technical staff who
provide accurate and reproducible analysis of tissues
using a blinded study design will permit objective
assessment for all studies. This centralization will be
more efficient and enhance quality control. This Core
will facilitate the following measurements:
(1) Quantification of AAAs
(2) Characterization of AAA composition
(3) Atherosclerosis lesion quantification and composition
(4) Plasma Measurements
1. King VL,
Trivedi D, Gitlin J.R., Loftin CD. (2006 )Selective
cyclooxygenase-2 inhibition with celecoxib decreases
angiotensin II-induced abdominal aortic aneurysm
formation in mice. Arterioscler Thromb Vasc Biol