< backPublications of Alan Daugherty, Ph.D., D.Sc.

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  1. Daugherty, A. (1981). Myocardial metabolism of calcium and cyclic nucleotides. Ph.D. thesis. University of Bath, England.
  2. Daugherty, A, and B. Woodward. (1981). Calcium and calcium slow-channel antagonists on cyclic nucleotide levels in the isolated rat heart. Journal of Molecular and Cellular Cardiology. 13: 843-854.  PMID 6271978
  3. Daugherty, A. and B. Woodward. (1985). Carbachol and cyclic GMP on the vulnerability to ventricular fibrillation is the rat isolated heart. British Journal of Pharmacology. 85: 621-627.   PMID 2992667
  4. Daugherty, A., L.G. Lange, B.E. Sobel, and G. Schonfeld. (1985). Aortic accumulation and plasma clearance of b-VLDL and HDL: Effects of diet-induced hypercholesterolemia in rabbits. Journal of Lipid Research. 26: 955-963.  PMID 4045321
  5. Daugherty, A., S.R. Thorpe, L.G. Lange, B.E. Sobel, and G. Schonfeld. (1985). Loci of catabolism of b-very low density lipoprotein in vivo delineated with a residualizing label: 125I-dilactitol tyramine. Journal of Biological Chemistry. 260: 14564-14570.  PMID 4055790
  6. Daugherty, A., K. N. Frayn, W. S. Redfern and B. Woodward. (1986). The role of catecholamines in the production of ischaemic-induced ventricular arrhythmias in the rat in vivo and in vitro. British Journal of Pharmacology. 87: 265-277.  PMID 2869812
  7. Daugherty, A., G. Schonfeld, B.E. Sobel and L.G. Lange. (1986). Metabolism of very low density lipoproteins after cessation of cholesterol feeding in rabbits: A factor potentially contributing to the slow regression of atheromatous plaques. Journal of Clinical Investigation. 77: 1108-1115.  PMID 3958182
  8. Fields, L., A. Daugherty and S.R. Bergmann. (1986). Effect of fatty acid on performance and lipid content of hearts from diabetic rabbits. American Journal of Physiology. 250: H1079-H1085.  PMID 3521333
  9. Daugherty, A., D.L. Rateri, G. Schonfeld and B.E. Sobel. (1987). Inhibition of cholesteryl ester deposition in macrophages by calcium entry blockers. An effect dissociable from calcium entry blockade. British Journal of Pharmacology. 91: 113-118.  PMID 3594069
  10. Tilton, R. G., P.A. Cole, J.D. Zions, A. Daugherty, K.B. Larson, S.P. Sutera, C. Kilo and J. R. Williamson. (1987). Increased ischemia-reperfusion injury to the heart associated with short term, diet-induced hypercholesterolemia in rabbits. Circulation Research. 60: 551-559.  PMID 3594739
  11. Daugherty A., K., Oida, B.E. Sobel and G. Schonfeld. (1988). The dependence of metabolic and structural heterogeneity of cholesteryl ester-rich very low density lipoproteins on the duration of cholesterol feeding in rabbits. Journal of Clinical Investigation. 82: 562-570.  PMID 3403717
  12. Cole, T. G., R. T. Kitchens, A. Daugherty and G. Schonfeld. (1988). An improved method of separation of triglyceride-rich lipoproteins by fast protein liquid chromatography. Pharmacia Comminuque. 4: 4-7.
  13. Daugherty, A., B.S. Zweifel, B.E. Sobel and G. Schonfeld. (1988). Isolation of low density lipoproteins from atherosclerotic vascular tissue of Watanabe Heritable Hyperlipidemic rabbits. Arteriosclerosis. 8: 768-777.  PDF file;  PMID 3196220
  14. Tilton, R.G., A. Daugherty, S.P. Sutera, K.B. Larson, M.P. Land, D.L. Rateri, C. Kilo, and J. R. Williamson. (1989). Myocyte contracture, vascular resistance, and vascular permeability after global ischemia in isolated hearts from alloxan-induced diabetic rabbits.  Diabetes. 38: 1484-1491. PDF abstract file; PMID 2620782
  15. Daugherty, A., B. Zweifel, and G. Schonfeld. (1989). Probucol attenuates the development of atherosclerosis in cholesterol-fed rabbits. British Journal of Pharmacology. 98: 612-618. PMID 2819336
  16. Daugherty, A., N.N. Becker, L.A. Scherrer, B.E. Sobel, J.J.H. Ackerman, J.W. Baynes and S.R. Thorpe. (1990) Non-invasive detection of protein metabolism by n.m.r. spectroscopy. Application of a novel 19F-residualizing label. Biochemical Journal. 264: 829-835.
  17. Parhoffer, K.G., A. Daugherty, M. Kinoshita, and G. Schonfeld. (1990). Enhanced clearance from plasma of low density lipoproteins containing a truncated apolipoprotein, B-90. Journal of Lipid Research. 31: 2001-2007. PMID 2086699
  18. Moerlein, S.M., A. Daugherty, B.E. Sobel, and M.J. Welch. (1991) Metabolic Imaging with Gallium-68- and Indium-111-Labeled Low-Density Lipoprotein  Journal of Nuclear Medicine. 32: 300-307. PDF file; PMID 1992034
  19. Daugherty, A., B.S. Zweifel, and G. Schonfeld. (1991) The effects of probucol on the progression of atherosclerosis in mature Watanabe heritable hyperlipidaemic rabbits. British Journal of Pharmacology. 103: 1013-1018.  PDF file; PMID 1878742
  20. Daugherty, A., and D.L. Rateri. (1991) Failure of the intracellular itinerary of b-very low density lipoproteins to augment cholesterol esterification in macrophages from Watanabe heritable hyperlipidemic rabbits. Journal of Biological Chemistry. 266: 17269-17275.   PDF file; PMID 1894618
  21. Daugherty, A, and D.L. Rateri. (1991) Heterogeneity of very low density lipoproteins: Factors influencing the ability of specific subfractions to modulate cholesterol metabolism in macrophages in vitro. Coronary Artery Disease. 2: 775-789.  PDF file
  22. Daugherty, A., M.R Kilbourn, C.S. Dence, B.E. Sobel, and S.R. Thorpe. (1992) Quantitative assessment of lipoprotein metabolism by positron emission tomography with an 18F-containing residualizing label.  Nuclear Medicine and Biology. 19: 411-416. PMID 1629030
  23. Ord, J.M., J.P. Hasapes, A. Daugherty, S.R. Bergmann, S.R. Thorpe, and B.E. Sobel. (1992) Imaging of thrombi with tissue-type plasminogen activator rendered enzymatically inactive and conjugated to a residualizing label. Circulation. 85: 288-297. PDF file; PMID 1728459
  24. Daugherty, A. and D.L. Rateri. (1992) Kinetics of tissue metabolism of b-very low density lipoproteins disparate rates of tissue accumulation during both normal and hypercholesterolemic states. Life Science Advances - Biochemistry. 10: 167-171.  PDF file
  25. Hasapes, J.P., A. Daugherty, J.E. Saffitz, and B.E. Sobel. (1992) Determinants of the distribution of radiolabeled congeners of tissue-type plasminogen activator and its modificaiton for improved clot imageing. Coronary Artery Disease. 3: 641-649.  PDF file
  26. Mankowitz, K., R. Seip, A. Daugherty, C.F. Semenkovich, A. Daugherty, and G. Schonfeld. (1992) Short-term interruption of training affects both fasting and post-prandial lipoproteins. Atherosclerosis. 95: 181-189.  PDF file; PMID 1418092
  27. Meeh, L.A., J.J.H. Ackerman, S.R. Thorpe, and A. Daugherty. (1992) Quantification of the accumulation and degradation of b-very low density lipoproteins in vivo using a 19F-containing residualizing label and N.M.R. spectroscopy. Biochemical Journal. 286: 785-792.  PDF file; PMID 1417737
  28. Wickline, S.A., R.A. Shapard, and A. Daugherty. (1993) Quantitative ultrasonic characterization of lesion composition and remodeling in atherosclerotic rabbit aorta.  13: 1543-1550. PDF file; PMID 7691167
  29. Baumann, D.S., M. Doblas, G. Schonfeld, G.A. Sicard and A. Daugherty. (1994) Probucol reduces the cellularity of aortic intimal thickening at anastomotic regions adjacent to prosthetic grafts in cholesterol-fed rabbits. Arteriosclerosis and Thrombosis. 14: 162-167.  PDF file; PMID 8274472
  30. Baumann, D.S., M. Doblas, A. Daugherty, G. A. Sicard, and G. Schonfeld. (1994). The role of cholesterol accumulation in prosthetic vascular graft anastomotic intimal hyperplasia. Journal of Vascular Surgery. 19: 435-445.  PDF file; PMID 8126856
  31. Daugherty, A., J.L. Dunn, D.L. Rateri, and J.W. Heinecke. (1994). Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions Journal of Clinical Investigation. 94:437-444.  PDF file; PMID 8040285
  32. Daugherty, A. and D.L. Rateri. (1994). Presence of LDL receptor-related protein/alpha 2-macroglobulin receptors in macrophages of atherosclerotic lesions from cholesterol-fed New Zealand and heterozygous Watanabe heritable hyperlipidemic rabbits.  Arteriosclerosis and Thrombosis. 14:2107-2024.  PDF file; PMID 7526898
  33. Noda-Heiny, H., A. Daugherty, and B.E. Sobel. (1995). Augmented urokinase receptor expression in atheroma. Arteriosclerosis, Thrombosis, and Vascular Biology. 15:37-43.  PDF file; PMID 7749814
  34. Roselaar, S.E., G. Schonfeld, and A. Daugherty. (1995) Enhanced development of atherosclerosis in cholesterol-fed rabbits by suppression of cell-mediated immunity.  Journal of Clinical Investigation. 96:1389-1394.  PDF file; PMID 7657813
  35. Shaish, A., A. Daugherty, F. O=Sulivan, G. Schonfeld, and J.W. Heinecke. (1995) Beta-carotene inhibits atherosclerosis in hypercholesterolemic rabbits.  96:2075-2082. PDF file; PMID 7560102
  36. Roselaar, S.E., P. Kakkanathu, and A. Daugherty. (1996) Lymphocyte populations in atherosclerotic lesions of apoE -/- and LDL receptor -/- mice. Decreasing density with disease progression. Arteriosclerosis, Thrombosis, and Vascular Biology. 16:1013-1018.  PDF file; PMID 8696940
  37. Fagan, A.M., G. Bu., Y. Sun, A. Daugherty, and D.M. Holtzman. (1996) Apolipoprotein E -containing high-density lipoprotein promotes neurite outgrowth and is a ligand for the low-density lipoprotein receptor-related protein. Journal of Biological Chemistry. 271: 30121-30125.  PDF file; PMID 8939961
  38. Cornicelli, J.A., K. Welch, B.J. Auerbach, S.J. Feinmark, and A. Daugherty. (1996) Mouse peritoneal macrophages contain abundant w-6 lipoxygenase activity that is independent of interleukin-4. Arteriosclerosis, Thrombosis, and Vascular Biology. 16:1488-1494.  PDF file; PMID 8977453
  39. Sendobry, S.M., J.A. Cornicelli, K. Welch, T. Bocan, B. Tait, B.K. Trivedi, N. Colbry, R.D. Dyer, S.J. Feinmark, and A. Daugherty. (1997) Attenuation of diet-induced atherosclerosis in rabbits with a highly selective 15-lipoxygenase inhibitor lacking significant antioxidant properties. British Journal of Pharmacology. 120:1199-1206.  PDF file; PMID 9105693
  40. Daugherty, A., E. Puré, D. Delfel-Butteiger, S. Chen, J. Leferovich, S. E. Roselaar, and D.J. Rader. (1997) The effects of total lymphocyte deficiency on the extent of atherosclerosis in apolipoprotein E-/- mice.  Journal of Clinical Investigation. 100: 1575-1580.  PDF file; PMID 9294126
  41. Daugherty, A., J.A. Cornicelli, K. Welch, S.M. Sendobry, and D.L. Rateri. (1997) Scavenger receptors are present on aortic endothelial cells in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 2369-2375.  PDF file PMID 9409203
  42. Roselaar, S.E., and A. Daugherty. (1997) Lipopolysaccharide decreases scavenger receptor mRNA abundance in vivo. Journal of Interferon and Cytokine Research. 17: 573-579.  PDF file; PMID 9335436
  43. Bocan, M.A., W.S. Rosebury, S.B. Mueller, S. Kuchera, K. Welch, A. Daugherty, and J.A. Cornicelli. (1998) A specific 15-lipoxygenase inhibitor limits the progression and monocyte-macrophage enrichment of hypercholesterolemia-induced atherosclerosis in the rabbit. Atherosclerosis. 136: 203-216.  PDF file; PMID 9543090
  44. Semenkovich, C.F., L. Coleman, and A. Daugherty. (1998) Effect of heterozygous lipoprotein lipase deficiency on diet-induced atherosclerosis in mice. Journal of Lipid Research. 39: 1141-1151.  PDF file; PMID 9643345
  45. Sendobry, S.M., J.A. Cornicelli, K. Welch, M.J. Grusby, and A. Daugherty. (1998) Absence of T lymphocyte_derived cytokines fails to diminish macrophage 12/15 lipoxygenase expression in vivo. Journal of Immunology. 161:1477-1482.  PDF file; PMID 9686614
  46. Roselaar, S.E. and A. Daugherty. (1998) Apolipoprotein E-deficient mice have impaired innate immune responses to Listeria monocytogenes in vivo.  Journal of Lipid Research. 39:1740-1743.  PDF file; PMID 9741685
  47. Cassis L., and A. Daugherty. (1999) Chronic angiotensin II infusion promotes atherogenesis in LDL receptor -/- mice. Annals of New York Academy of Sciences. 892:108-118.  PDF file; PMID 10842656
  48. Cornicelli, J.A., D. Delfel-Butteiger, D.L. Rateri, K. Welch, and A. Daugherty. (2000) Interleukin-4 augments acetylated LDL-induced cholesterol esterification in macrophages.  Journal of Lipid Research. 41:376-383.  PDF file; PMID 10706585
  49. Whitman, S.C., A. Daugherty, and S.R. Post. (2000) Regulation of acetylated low density lipoprotein uptake in macrophages by pertussis toxin-sensitive G proteins.  Journal of Lipid Research. 41:807-813.  PDF file; PMID 10787441
  50. Daugherty, A. and L.A. Cassis. (2000) Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice.  Journal of Clinical Investigation. 105:1605-1612.  PDF file; PMID 10841519
  51. Daugherty A, Whitman SC, Block AE, Rateri DL.  (2000) Polymorphism of class A scavenger receptors in C57BL/6 mice. Journal of Lipid Research. 41: 1568-1577.  PDF file; PMID 11013298
  52. Whitman, S.C., P. Ravisankar, Elam, H., and A. Daugherty. (2000) Exogenous interferon-gamma enhances atherosclerosis in apolipoprotein E-/- mice. American Journal of Pathology. 157: 1819-1824.  PDF file; PMID 11106554
  53. Whitman, S.C., A. Daugherty, and S.R. Post. (2000) Macrophage colony-stimulating factor rapidly enhances beta-migrating very low density lipoprotein metabolism in macrophages through activation of a Gi/o protein signaling pathway.  Journal of Biological Chemistry. 275: 35807-35813.  PDF file; PMID 10964909
  54. Gairola, C.G., and A. Daugherty. Sidestream cigarette smoke accelerates atherosclerosis in apolipoprotein E-/- mice. Atherosclerosis. 156: 49-56. PDF file; PMID 11368996
  55. Lee Y.W., H. Kuhn, B. Hennig, A. Daugherty, and M. Toborek. Interleukin 4 induces transcription of the 15-lipoxygenase I gene in human endothelial cells.  Journal of Biological Chemistry. 42: 783-791.  PDF file; PMID 11352986
  56. Daugherty, A., N. Kosswig, J.A. Cornicelli, S.C. Whitman, S. Wolle, D.L. Rateri. (2001) Macrophage specific expression of class A scavenger receptors enhances granuloma formation in the absence of increased lipid deposition. Journal of Lipid Research. 42: 1049-1055. PDF file; PMID 11441131
  57. Hansen, P.R., M. Chew, J. Zhou, A. Daugherty, N.H.H. Heegaard, P. Jensen, S. Mouritsen, and E. Falk. (2001) Freunds adjuvant alone is antiatherogenic in apoE-deficient mice and specific immunization against TNF-alpha confers no additional benefit. Atherosclerosis. 158: 87-94. PDF file; PMID 11500178
  58. Daugherty, A, M.W. Manning, and L. A . Cassis. (2001) Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis.  British Journal of Pharmacology. 134: 865-870 PDF file; PMID 11606327
  59. Whitman, S.C., P. Ravisankar, P., and A. Daugherty. (2002) Interleukin-18 enhances atherosclerosis in apolipoprotein E -/- mice through release of interferon-gamma Circulation Research. 10.1161/hh0202.105292. PDF file; PMID 11834721
  60. King, V.L., S.J. Szilvassy, and A. Daugherty. (2002) Interleukin-4 deficiency decreases atherosclerotic lesion formation in a site-specific manner in female LDL receptor-/- mice.  Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 456-461. PDF file; PMID 11884290
  61. King, V.L., S.J. Szilvassy, and A. Daugherty. (2002) Interleukin- 4 deficiency promotes gall stone formation. Journal of Lipid Reseach. 43: 768-771 PDF file; PMID 11971948
  62. Whitman, S.C., P. Ravisankar, H. Elam, A. Daugherty. (2002) Interferon-gamma deficiency exerts gender specific effects on atherogenesis in apolipoprotein E -/- mice. Journal of Interferon and Cytokine Research. 22: 661-670. PDF file; PMID 12162876
  63. Hennig B., P. Meerarani, R. Slim, M. Toborek, A. Daugherty, A. Silverstone, and L.W. Robertson. (2002) Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence. Toxicol. Sci. 181: 174-183. PDF file; PMID 12079426
  64. Whitman, S.C, D.L. Rateri, S.J. Szilvassy, J.A. Cornicelli, and A. Daugherty. (2002) Macrophage specific expression of class A scavenger receptors decreases atherosclerosis in LDL receptor -/- mice. Journal of Lipid Research. 43: 1201-1208 PDF file; PMID 12177164
  65. Webb, N.R., de Beer, M.C., Yu, J., Kindy, M.S., Daugherty, A., van der Westhuyzen, D., and de Beer, F.C. (2002) Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-A, but not apoB, in human apoB transgenic mice. Journal of Lipid Research. 43: 1421-1428 PDF file; PMID 12235137
  66. Webb, N.R., M.A. Bostrom, S.J. Szilvassy, D.R. van der Westhuyzun, A. Daugherty, and F.C. de Beer. (2003) Macrophage-expressing Group IIA sPLA2 increases atherosclerotic lesion formation in LDL receptor-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 23:263-268. PDF file; PMID 12588769
  67. Manning, M.W., L.A. Cassis, and A. Daugherty. Differential effects of doxycycline, a broad spectrum inhibitor of matrix metalloproteinases, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysm formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 23:468-474. PDF file; PMID 12615694
  68. Sundell, C.L, P.K. Somers, C.Q. Meng., L. K. Hoong, K-L. Suen, R.R. Hill, L.K. Landers, A. Chapman, L.K. Ollif, C. Phanhthourath, C. Kunsch, A. Daugherty, U. Saxena, M.A. Wasserman, and R. M. Medford AGI-1067: a multifunctional phenolic antioxidant, lipid modulator, anti-inflammatory and anti-atherosclerotic agent. Journal of Pharmacology and Experimental Therapeutics. 305: 1116-1123. PDF file; PMID 12626663
  69. Chew, M., J. Zhou, A. Daugherty, T. Eriksson, S. Ellerman-Eriksen, P.R. Hansen, and E. Falk. (2003) Thalidomide inhibits early atherogenesis in apoE deficient mice. APMIS.: acta pathologica, microbiologica et immunologica Scandinavica 2003; 111 (Suppl 109): 113-116. PDF abstract; PMID 12874961
  70. Urbas, A, M. W. Manning, A. Daugherty, L.A. Cassis, and R.A Lodder. (2003) Near-infrared spectrometry of abdominal aortic aneurysm in the apoE -/- mouse. Analytical Chemistry. 75: 3318-3323 PDF file; PMID 14570222
  71. Saraff, K., F. Babamusta, L.A. Cassis, and A. Daugherty. (2003) Aortic dissection precedes formation of aneurysms and atherosclerosis in AngII-infused apoE deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1621-1625. PDF file; PMID 12855482
  72. Kosswig, N., A. Daugherty, and S.R. Post. (2003) Class A scavenger receptor mediated adhesion and internalization require distinct cytoplasmic domains. Journal of Biological Chemistry. 278: 34219-34225 PDF file; PMID 12819208
  73. Lyngdorf, L.G., S. Gregersen, A. Daugherty, and E. Falk. (2003) Paradoxical reduction of atherosclerosis in apoE-deficient mice with obesity-related type 2 diabetes. Cardiovascular Research. 59: 854-862 PDF file; PMID 14553825
  74. Cassis, L.A., J. Huang, M.C. Gong, and A. Daugherty. (2004) Role of metabolism and receptor responsiveness in the attenuated responses to angiotensin II in mice compared to rats. Regulatory Peptides. 117: 107-116. PDF file; PMID 14700746
  75. Whitman, S.C., D.L. Rateri, S.J. Szilvassy, W. Yokoyama, and A. Daugherty (2004) Depletion of natural killer cell function decreases atherosclerosis in LDL receptor -/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1049-1054. PDF file; PMID 14988092
  76. Henriques TA, Huang J, D'Souza SS, Daugherty A, Cassis LA.  (2004) Orchiectomy, but not ovariectomy, regulates angiotensin II-induced vascular diseases in apolipoprotein E deficient mice. Endocrinology.  2004 Aug;145(8):3866-72  PDF file; PMID 15105380
  77. Boustany, C., K. Bharadwaj . A. Daugherty, D. Brown, D. Randall, and L.A. Cassis. (2004) Activation of the systemic and adipose renin angiotensin system in rats with diet-induced obesity and hypertension. American Journal of Physiology. 287: R943-949. PDF file; PMID 15191907
  78. Homeister, J.W., A. Daugherty, and J.B. Lowe. (2004) Alpha(1,3)fucosyltransferases FucT-IV and FucT-VII control susceptibility to atherosclerosis in apolipoprotein E-/- mice.  Arteriosclerosis, Thrombosis, and Vascular Biology, 2004 Oct;24(10):1897-903.  PDF file; PMID 15308551
  79. Whitman, S.C., P. Veeraraghavan, E. M. Kurowska, J. A. Manthey, A. Daugherty. Nobiletin, a citrus flavonoid isolated from tangerines, selectively inhibits class A scavenger receptor-mediated metabolism of acetylated LDL by mouse macrophages. Atherosclerosis. 178: 25-32. PDF file; PMID 15585197
  80. Daugherty, A., D.L. Rateri, H. Lu, T. Inagami, and L.A. Cassis. (2004) Hypercholesterolemia stimulates angiotensin peptide synthesis and contributes to atherosclerosis through the AT1A receptor. Circulation. 110: 3849-3857. PDF file; PMID 15596561
  81. Cassis L.A., M.J. Helton, D. Howatt, V.L. King, and A. Daugherty. (2005) Aldosterone does not mediate angiotensin II-induced atherosclerosis and abdominal aortic aneurysms. British Journal of Pharmacology. 144: 443-448. PDF file; PMID 15655500
  82. Hennig B., G. Reiterer, M. Toborek, S.V. Mateev, A. Daugherty, E. Smart, and L.W. Robertson. (2005) Dietary fat interacts with PCBs to induce changes in lipid metabolism in LDL receptor deficient mice. Environmental Health Perspectives. 113: 83-87. PDF file; PMID 15626652
  83. Gavrila, D, W.G, Li, M.L. McCormick, M. Thomas, A. Daugherty, L. A. Cassis, F.J. Miller, Jr, L.W. Oberley, K.C. Dellsperger, and N.L. Weintraub. Vitamin E inhibits abdominal aortic aneurysms formation in angiotensin II-infused, apolipoproteinE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 46: 1812-1822. PDF file; PMID 15933246
  84. Guo, Z., W. Su, S. Allen, H. Pang, A. Daugherty, E.J. Smart, and M.C. Gong. (2005) Cox-2 upregulation and vascular smooth muscle contractile hyperreactivity in spontaneous diabetic db/db mice. Cardiovascular Research. 67: 723-735. PDF file; PMID 15885672
  85. Reiterer, G., R. McDonald, E.J. Smart, A. Daugherty, M. Toborek, and B. Henning. (2005) Zinc deficiency increases plasma lipids and atherosclerosis markers in LDL-R deficient mice. Journal of Nutrition. 135: 2114-2118. PDF file; PMID 16140885
  86. Lutgens, E., S.P.M. Lutgents, B.C.G. Faber, S. Heeneman, M.M.J. Gijbels, M.P.J. de Winther, P. Frederiks, I. Van der Made, A. Daugherty, A.M., Sijbers, A. Fisher, C.J. Long, P. Saftig, D. Black, M.J. A.P. Daemen, and K.B.J.M. Cleutjens. (2005) Disruption of the cathespin K gene reduces atherosclerosis progression, induced plaque fibrosis, but accelerates macrophage foam cell formation. Circulation, 113: 98-107. PDF file; PMID 16365196
  87. Babamusta, F., D. L. Rateri, J.J. Moorleghen, D. A. Howatt, X.A. Li., and A. Daugherty (2006) Angiotensin II induced site specific intra-laminar hemorrhage in macrophage colony stimulating factor deficient mice. Atherosclerosis. 186: 282-290. PDF file; PMID 16153649
  88. Barisione, C, D.L. Howatt, J. Moorleghen, D.L. Rateri, and A. Daugherty. (2006) Rapid dilation of the abdominal aorta during infusion of angiotensin II detected noninvasively by high frequency ultrasound. Journal of Vascular Surgery. Journal of Vascular Surgery. 44:372-6. PDF file; PMID 16890871
  89. Mauldin, J.P., A. Mulya, A. Gebre, J.S. Parks, A. Daugherty, and C.C. Hedrick. (2006) Reduction in ABCG1 in type 2 diabetic mice increases macrophage foam cell formation. Journal of Biological Chemistry. 281: 21216-21224. PDF file; PMID 16723355

  90. Thomas, T., M.L. McCormick, D. Gavrila, F.J. Miller, A. Daugherty, L.A. Cassis, K.C., Dellsperger, and N.L. Weintraub. (2006) Deletion of p47phox attenuates angiotensin II-induced aortic aneurysm formation in apolipoprotein E-deficient mice. Circulation. 114: 404-413. PDF file; PMID 16864727

  91. Cassis, L.A., D.L. Rateri, H. Lu, and A. Daugherty. (2007). Angiotensin II induction of atherosclerosis and abdominal aortic aneurysms requires expression of AT1a receptors on non-bone marrow derived cells. Arteriosclerosis Thrombosis and Vascular Biology. 27: 380-386. PDF file; PMID 17158350

  92. Lu, H., C. Boustany Kari, A. Daugherty, and L.A. Cassis. (2007). Angiotensin II increases adipose angiotensinogen expression. American Journal of Physiology - Endocrinology and Metabolism. 115: E1280-1287.  PDF file; PMID 17213477

  93. King, V.L., L.A. Cassis and A. Daugherty. (2007) Interleukin-4 does not influence development of hypercholesterolemia or angiotensin II-induced atherosclerotic lesions in apoE-/- mice. American Journal of Pathology. 171: 2040-2047.  PDF file; PMID 18055554

  94. Shen, H., R. MacDonald, D. Bruemmer, A. Stromberg, A. Daugherty, X. Li, M. Toborek, and B. Hennig (2007) Zinc deficiency alters lipid metabolism in LDL receptor deficient mice treated with rosiglitazone.  Journal of Nutrition. 137: 2339-2345.  PDF file; PMID 17951467

  95. Lu, H., D.L. Rateri, D.L. Feldman, E. R.J. Charnigo Jr, A. Fukamizu, J. Ishida, E.G. Oesterling, L. A. Cassis, and A. Daugherty. (2008) Renin Inhibition reduces hypercholesterolemia-induced atherosclerosis: the contribution of renin from bone marrow-derived cells. Journal of Clinical Investigation. 118: 984-993.  PDF file; PMID 18274671

  96. Henriques T, X. Zhang, F.B. Yiannikouris, A. Daugherty, and L.A. Cassis. (2008) Androgen increases AT1a receptor expression in abdominal aortas to promote angiotensin II-induced abdominal aortic aneurysms in apolipoprotein E deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. Jul;28(7):1251-6 PDF file; PMID 18451329

  97. Deevska, G., K. Rozenova, N., Giltiay, M. Chambers, J., White, B.B. Boyanovsky, J., Wei, A., Daugherty, E.J., Smart, M.B. Reid, A.H. Merrill Jr., and M. Nikolova-Karakashian (2008) Acid sphingomyelinase deficiency prevents diet-induced hepatic triacylglycerol accumulation and hyperglycemia in mice. Journal of Biological Chemistry 284:8359-68. PDF file; PMID 19074137

  98. Bolick, D.T., M.D. Skaflen, S-C. Kwon, D.A. Howatt, A. Daugherty, Ravichandran, K.S. and C.C. Hedrick. (2008) G2A deficiency in mice promotes macrophage activation and atherosclerosis. Circulation Research. 104: 318-327. PDF file; PMID 19106413. 

  99. King VL, Lin AY, Kristo F, Thomas JT, Anderson TJ, Ahluwalia N, Hardy GJ, Owens AP 3rd, Howatt DA, Shen D, Tager AM, Luster AD, Daugherty A, Gerszten RE. Interferon-gamma and the interferon-inducible chemokine, CXCL10, protect against aneurysm formation and rupture. Circulation. Jan 27;119(3):426-35  PDF file; PMID 19139386

  100. Cassis LA, Gupte M, Thayer S, Zhang X, Charnigo R, Howatt DA, Rateri DL, Daugherty AANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice.  2009 May;296(5):H1660-5.  Am J Physiol Heart Circ Physiol. PDF file; PMID 19252100

  101. Guo, L., Z. Song, M. Li, Q. Wu, D. Wang, H. Feng, P. Bernard, A. Daugherty, B. Huang, and X-A Li (2009). Scavenger receptor BI protects against septic death through its role in modulating inflammatory response. Journal of Biological Chemistry. 284 (30): 19826-19834. PDF File; PMID 19491399

  102. Daugherty, A., D.L. Rateri, H. Lu, and A. Balakrishnan. (2009). Measuring blood pressure in mice and rats using volume pressure recordings, a tail cuff method. Journal of Visualized Experiments. DOI 10.3791/1291. PDF File; PMID 19488026.

  103. Police, S.B., S. Thatcher, R. Charnigo, A. Daugherty, and L.A. Cassis. (2009). Obesity promotes inflammation in periaortic adipose tissue and angiotensin II-induced abdominal aortic aneurysm formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1458-1464. PDF File; PMID 19608970

  104. Golledge, J., B. Cullen, C. Rush., C.S. Moran., E. Secomb., F. Wood, A. Daugherty, J.H. Campbell, and P.E. Norman. (2009). Peroxisome proliferator-activated receptor ligands reduce aortic dilatation in a mouse model of aortic aneurysm. Atherosclerosis. 201: 51-56. PDF File; PMID 19926086.

  105. Owens, A.P III, V. Subramanian J.J. Moorleghen, C.A. McNamara, L.A. Cassis, and A. Daugherty. (2010). Angiotensin II induces a Region-Specific Hyperplasia of the ascending aorta through regulation of inhibitor of differentiation 3. Circulation Research. 106: 611-619. PDF File; PMID: 20019328.

  106. Daugherty, A., D. A. Howatt, A.P. Owens, I.F. Charo, D.L. Rateri, and L.A. Cassis. (2010). Deficiency of CCR2 reduces angiotensin II -induced atherosclerosis and aneurysm formation in apolipoprotein E -/- mice. Clinical Science. 106: 681-689. PDF File; PMID 20088827.

  107. Uchida, H.A., F. Kristo, D.L. Rateri, H. Lu, R. Charnigo, L.A. Cassis, and A. Daugherty. (2010). Total lymphocyte deficiency attenuates angII-induced atherosclerosis but not abdominal aortic aneurysms in apoE deficient mice. Atherosclerosis. 211: 399-403. PDF File; PMID 20362292.

  108. Gairola, C.G., D.A. Howatt, and A. Daugherty. (2010). Dietary coenzyme Q10 does not protect against cigarette smoke-augmented atherosclerosis in apoE-deficient mice. Free Radical Biology and Medicine. 48: 1535-1539. PDF File; PMID 20227489.

  109. Zhao, Y., D.A. Howatt, F. Gizard, T. Nomiyama, H.M. Findeisen, E.B. Heywood, K.L. Jones, O.M. Conneely, A. Daugherty, and D. Bruemmer. (2010). Deficiency of the NR4A orphan nuclear receptor NOR1 decreases monocyte adhesion and reduces atherosclerosis. Circulation Research. 107: 501-511. PDF File; PMID 20558821.

  110. Subramanian, V., J. Golledge, T. Ijaz, D. Bruemmer, and A. Daugherty. (2010). Pioglitazone-induced reductions in atherosclerosis occur via smooth muscle cell-specific interaction with PPARγ. Circulation Research. 107(8): 953-958. PDF File; PMID 20798360.

  111. Zack, M., P. Shridas, B.B. Boyanovsky, W.Bailey, K. Forrest, D. A. Howatt, M.H. Gelb, F.C. de Beer, A. Daugherty, and N.R. Webb. (2011). Group X secretory phospholipase A2 augments angiotensin II-induced inflammatory responses and abdominal aortic aneurysm formation in apoE-deficient mice. Atherosclerosis. 214; 58-64. PDF File; PMID 20833395.

  112. Findeisen, H. M., F. Gizard, Y. Zhao, D. Cohn, E.B. Heywood, K.L. Jones, D.A. Howatt, A. Daugherty, and D. Bruemmer. (2010). Telomerase-deficiency in bone marrow-derived cells attenuates angiotensinII-induced abdominal aortic aneurysm formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 2011 Feb;31(2):253-60. Epub 2010 Nov 18. PDF File; PMID 21088250.

  113. Rateri, D.L., J.J. Moorleghen, A. Balakrishnan, A.P. Owens III, D.A. Howatt, V. Subramanian, A. Poduri, R. Charnigo, L.A. Cassis, and A. Daugherty. (2011). Endothelial cell-specific deficiency of angII type 1a receptors attenuates angII-induced thoracic aortic aneurysms in LDL receptor -/- mice. Circulation Research. 2011 Mar 4;108(5):574-81. Epub 2011 Jan 20. PDF File; PMID 21252156.

  114. Thatcher, S.E., X. Zhang, D.A. Howatt, H. Lu, S. Gurley, A. Daugherty and L.A. Cassis. (2011). ACE2 deficiency in Whole Body or bone marrow-derived cells increases atherosclerosis in LDL receptor -/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 2011 Jan 20. PDF File; PMID 21252069.

  115. Thatcher, S.E., X. Zhang, D.A. Howatt, H. Lu, S. Gurley, A. Daugherty and L.A. Cassis. (2011). Angiotensin-converting enzyme 2 deficiency in whole body or bone marrow-derived cells increases atherosclerosis in low-density lipoprotein receptor-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 2011 Apr;31(4):758-65. Epub 2011 Jan 20. (PMID 21252069)

  116. Wang, J.A., W.A. Chen. Y. Wang, S. Zhang, H. Bi, B. Hong, Y. Luo, A. Daugherty, and Xie X. (2011). Statins exert differential effects on angiotensin II-induced atherosclerosis, but no benefit for abdominal aortic aneurysms. Atherosclerosis. 2011 Jul;217(1):90-6. Epub 2011 Mar 10. (PMID 21481872)

  117. Xie, X., Y. Wang, S. Zhang, G. Zhang, Y. Xu, H. Bi, A. Daugherty, and J-A. Wang. (2011). Chinese red yeast rice attenuates the development of angiotensin II-induced abdominal aortic aneurysm and atherosclerosis. Journal of Nutritional Biochemistry. 2012 Jun;23(6):549-56. Epub 2011 Jul 20. (PMID 21764282)

  118. Zhang, X., J. Hurng, D.L. Rateri, A. Daugherty, G. W. Schmid-Schönbein, and H.Y. Shin. (2011). Membrane cholesterol modulates the fluid shear stress response of polymorphonuclear leukocytes via its effects on membrane fluidity. American Journal Physiology - Cell Physiology. 2011 Aug;301(2):C451-60. Epub 2011 Apr 27. (PMID 21525434)

  119. 119. Rateri, D.L., D.A. Howatt, J.J. Moorleghen, R. Charnigo, L.A. Cassis, and A. Daugherty. (2011). Prolonged infusion of angiotensin II in apoE(-/-) mice promotes macrophage recruitment with continued expansion of abdominal aortic aneurysm. American Journal of Pathology. 2011 Sep;179(3):1542-8. Epub 2011 Jul 19. (PMID 21763672).

  120. Li., H., E.T. Weatherford, D.R. Davis, H.L. Keen, J.L. Grobe, A. Daugherty, L.A. Cassis, A.M. Allen, and C.D. Sigmund. (2011). Angiotensin II AT1a receptors in the renal proximal tubule regulate blood pressure. American Journal of Physiology: Regulatory, Integrative, and Comparative Physiology. 2011 Oct;301(4):R1067-77. Epub 2011 Jul 13. (PMID 21753145).

  121. Zhang, G., B. Xiang, R.C. Skoda, A. Daugherty, S.S. Smyth, X. Du, and Z. Li. (2011). Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation. Blood. 2011 Sep 29;118(13):3670-9. Epub 2011 Jul 29. (PMID 21803853)

  122. Feng, H., L. Guo. D. Wang, H. Gao, G. Hou, Z. Zheng, J. Ai, O. Foreman, A. Daugherty, and X-A Li, (2011). Deficiency of scavenger receptor BI leads to impaired lymphocyte homeostasis and autoimmune disorders in mice. Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2543-51. (PMID 21836069)

  123. Uchida, H.A., A. Poduri, V. Subramanian, L.A. Cassis, and A. Daugherty. (2011). uPA deficiency in bone marrow-derived cells augments rupture of angiotensin II-induced abdominal aortic aneurysms. Arteriosclerosis, Thrombosis, and Vascular Biology. 2011 Dec;31(12):2845-52. Epub 2011 Aug 25. (PMID 21868698)

  124. Lu, H., A. Balakrishnan, D.A. Howatt, C. Wu, R. Charnigo, G. Liau, L.A. Cassis, and A. Daugherty. (2011). Comparative effects of different modes of renin angiotensin system inhibition on hypercholesterolemia-induced atherosclerosis. British Journal of Pharmacology. 2012 Mar;165(6):2000-8. doi: 10.1111/j.1476-5381.2011.01712.x. (PMID 22014125)

  125. Guo, L., M. Chen, Z. Song., A. Daugherty, and X-A. Li. (2011). C323 of SR-BI is required for SR-BI-mediated HDL binding and cholesteryl ester uptake. J Lipid Res. 2011 Dec;52(12):2272-8. Epub 2011 Sep 14.   (PMID 21917726).

  126. Owens III, A.P., D.L. Rateri, D.A. Howatt, K.J. Moore, P.S. Tobias, L.K. Curtiss, H. Lu., L. A. Cassis, and A. Daugherty. (2011). MyD88 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation independent of signaling through toll-like receptors 2 and 4. Arteriosclerosis, Thrombosis, and Vascular Biology. 2011 Dec;31(12):2813-9. Epub 2011 Sep 29. (PMID 21960563).

  127. Habegger, K.M., E. Grant, P.T. Pfluger, D.-P.-Tilve, A. Daugherty, D. Bruemmer, M. H. Tschöp, and S. Hofmann. (2011). Ghrelin receptor deficiency does not affect diet-induced atherosclerosis in low-density lipoprotein receptor-null mice. Frontiers in Systems and Translational Endocrinology. 2:67. doi: 10.3389/fendo.2011.00067.

  128. Batifoulier-Yiannikouris, F., M. Karounos, V. English, D.L. Rateri, A. Daugherty, and L. A. Cassis. (2011). Adipocyte-specific deficiency of angiotensinogen decreases plasma angiotensinogen concentration and systolic blood pressure in male mice. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology. 2012 Jan 15;302(2):R244-51. Epub 2011 Nov 9. (PMID 22071160)

  129. Subramanian, V, J. Golledge, E.B. Heywood, D. Bruemmer, and A. Daugherty. (2011). Regulation of PPARγ by angiotensin II via TGF-β1 activated p38 MAP kinase in aortic smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 2012 Feb;32(2):397-405. Epub 2011 Nov 17. (PMID 22095985).

  130. Wang, S., V. Subramanian , H. Lu, D.A. Howatt, J.J. Moorleghen, R. Charnigo, L.A. Cassis, and A. Daugherty. (2011). Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms. Atherosclerosis. 2012 Feb;220(2):375-80. Epub 2011 Nov 19. (PMID 22153700)

  131. Owens III, A.P., F.H. Passam, S. Antoniak, S.M. Marshall, A.L. McDaniel, L. Rudel, J.C. Williams, B.K. Hubbard, J.-A. Dutton, J. Wang, P.S. Tobias, L.K. Curtiss, A. Daugherty, D. Kirchhofer, J. Luyendyk, P.M. Moriarty, S. Nagarajan, B.C. Furie, B. Furie, D.G. Johns, R.E. Temel, and N. Mackman. (2012). Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monekys is inhibited by simvastatin. Journal of Clinical Investigation. 2012 Feb 1;122(2):558-68. doi: 10.1172/JCI58969. Epub 2012 Jan 3. (PMID 22214850)

  132. Si, Y. ,J. Ren, P. Wang, D.L. Rateri, A. Daugherty, X-D. Shi, K.C. Kent, and B. Liu. (2012). Protein kinase C-delta mediates adventitial cell migration through regulation of monocyte chemoattractant protein-1 expression in a rat angioplasty model. Arteriosclerosis, Thrombosis, and Vascular Biology 2012 Apr;32(4):943-54. Epub 2012 Feb 9. (PMID 22328773).

  133. Lu, H, C. Wu, D. A. Howatt, A. Balakrishnan, T. Ijaz, R.J. Charnigo Jr, L.A. Cassis, and A. Daugherty. (2012). Dietary sodium concentrations have differential effects on blood pressure and atherosclerosis in hypercholesterolemic mice. Journal Nutritional Biochemistry. ePub 2012 Jun 15 . (PMID 22705323)

  134. Zhang, X., S.E. Thatcher, D.L. Rateri, D. Bruemmer, R. Charnigo, A. Daugherty, and L.A. Cassis. (2012). Transient exposure of neonatal female mice to testosterone abrogates sexual dimorphism of angiotensin II–induced abdominal aortic aneurysms. Circulation Research. 2012 May 25;110(11):e73-85. Epub 2012 Apr 26. (PMID 22539767)

  135. Han, S.G., D.A. Howatt, A. Daugherty, and C.G. Gairola. (2012). Atherogenic and pulmonary responses of apoE- and LDL receptor-deficient mice to sidestream cigarette smoke. Toxicology. 2012 Sep 28;299(2-3):133-8. Epub 2012 Jun 1. (PMID 22659316)

back to topPublished Sequences

  1. Rateri, D.L., S. C. Whitman, and Daugherty, A. (1999) Sequence of cDNA for class A scavenger receptor from C57BL/6 mouse strain. GeneBank. Accession number AF203781

back to topBooks

  1. Daugherty, A., L.M. Cusumano and W. Jack. (1987). Therapeutic Advances in Hyperlipidemia and Atherosclerosis. Medstrategy Inc., St. Louis.
  2. Daugherty A., L.M. Cusumano and W. Jack (1989). Therapeutic Advances in Hyperlipidemia and Atherosclerosis. Update I. Medstrategy Inc., St. Louis.
  3. Daugherty A., P. Blank, and W. Jack (1990). Therapeutic Advances in Hyperlipidemia and Atherosclerosis. Update II. Medstrategy Inc., St. Louis.
  4. Daugherty, A. and J.W. Baynes - editors - (1991). Radical Therapies - Roles of antioxidants in disease treatment. Medstrategy Inc., St. Louis.
  5. Daugherty, A. (1992). Highlights of the XI International Symposium on Drugs Affecting Lipid Metabolism. Medstrategy Inc., St. Louis.
  6. Daugherty, A. and W. Jack. (1993). Atherosclerosis: Etiology and Therapeutic Strategies. Medstrategy Inc., St. Louis.

back to topInvited Chapters in Books

  1. Daugherty, A. (1990). Probucol reduces lipid deposition in vivo in atherosclerotic lesions of rabbits with hypercholesterolemia of either genetic or dietary origin. Xth International Symposium on Drugs Affecting Lipid Metabolism. Elsevier Scientific Publishers B.V. Amsterdam.
  2. Schonfeld, G, E.S. Krul, P. Talmud, A. Daugherty, and S.E. Humphries. (1990). Hypobetalipoproteinemia associated with truncated forms of apoB in a USA kindred. Xth International Symposium on Drugs Affecting Lipid Metabolism. Elsevier Scientific Publishers B.V. Amsterdam.
  3. Daugherty, A. and J.W. Heinecke. (1995). Epidemiology and risk factors in atherosclerosis. Pg 81-90. Vascular Surgery: Theory and Practice. Ed. A. Callow and A. Ernst. Appleton and Lange. Stamford, CT.  PDF file
  4. Heinecke, J.W. and A. Daugherty. (1995). Pathogenesis of atherosclerosis. Pg 91 - 103. Vascular Surgery: Theory and Practice. Ed. A. Callow and A. Ernst. Appleton and Lange. Stamford, CT.  PDF file
  5. Daugherty, A. and G. K. Hansson. Lymphocytes in Atherosclerosis. (2000). In Expression, Cell Interactions and Oxidation : New Foci in Atherosclerosis Research. Pg 230-249. Ed. R Dean and D. Kelly, Oxford University Press, Oxford, UK. PDF file
  6. Hennig, B., V Saraswathi, A. Daugherty, and M. Toborek.  (2002) Fatty acid-induced endothelial cell activation.  Pg 37-40.  Atherosclerosis:  Risk Factors, Diagnosis, and Treatment.  Ed G.M. Kostner.  Medimond Inc, Bologna, Italy.
  7. Daugherty, A. and S.C. Whitman. Use of the mouse for studying atherosclerosis. (2003) The Transgenic Mouse: Methods and Protocols. Methods of Molecular Medicine.  Pg 293-309. Ed. M. Hofker. Humana Press.
  8. Daugherty, A. and D.L. Rateri (2006) Hyperlipidemia-induced atherosclerosis.  A Handbook of Mouse Models for Cardiovascular Diseases. pg. 53-66. Ed Q. Xu, Wiley, London.  PDF file
  9. Wang, Y.X. Cassis, L.A. and Daugherty, A. (2006). Angiotensin II-induced abdominal aortic aneurysms. A Handbook of Mouse Models for Cardiovascular Diseases. pg 125-146. Ed Q. Xu, Wiley, London.  PDF file
  10. Lu, H., D.L. Rateri, and A. Daugherty (2007) Immunostaining of mouse atherosclerotic lesions.  Vascular Biology Protocols. Eds. Sreejayan and J. Ren. Human Press, Totowa, New Jersey.

  11. Daugherty A, Lu H, Howatt DA, Rateri DL. (2009) Modes of defining atherosclerosis in mouse models: relative merits and evolving standards. Methods of Molecular Biology. 573: Pg 1-15. PMID 19763919

back to topInvited Reviews

  1. Daugherty, A. and G. Schonfeld. (1985). Roles of lipoproteins in the initiation and development of atherosclerosis. Pharmacol Therap. 31: 337-355.  PDF file
  2. Daugherty, A. and D.L. Rateri. (1993) Pathogenesis of atherosclerotic lesions. Cardiol Rev. 1: 157-166.  PDF file
  3. Daugherty, A. (1993). Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Curr Opin Lipid. 4: VI-20-VI-25.
  4. Daugherty, A. (1994). Lipoprotein receptors in atherosclerotic lesions. Relation to the pathology of atherosclerosis. Coron Art Dis. 5: 211-215.  PDF file
  5. Daugherty, A. (1994). Advances in Cell Biology of Atherosclerosis - Overview as Guest Editor. Coron Art Dis. 5: 185-188.  PDF file
  6. Daugherty, A. and S.E. Roselaar. (1995). Lipoprotein oxidation as a mediator of atherogenesis: Insights from pharmacological studies. Cardiovasc Res. 29: 297-311.  PDF file
  7. Daugherty, A. (1995). Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Curr Opin Lipidi. 6: U106-U112.
  8. Daugherty, A. (1997). Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Curr Opin Lipid. 8: U11-U12.  PDF file
  9. Daugherty, A. (1997). Lymphocytes in atherosclerotic lesions - Bystanders of active participants. Atherosclerosis Alert. 2: 395-400.
  10. Daugherty, A. (1998) Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Curr Opin Lipid. 9:179-180.  PDF file
  11. Daugherty, A. (1998) Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Curr Opin Lipid. 9:613-615.
  12. Daugherty, A. (2000) Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Curr Opin Lipid. 11:335-337.  PDF file
  13. Daugherty, A., S. C. Whitman, and D.L. Rateri (2000) Class A scavenger receptors. Curr Opin Cardiovasc Pulm Renal Invest Drugs. 2:223-232. PDF file
  14. Daugherty, A. (2001) Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Curr Opin Lipid. 12:467-469.  PDF file
  15. Daugherty, A. (2002) Models of vascular disease in knockout mice. Am J Med Sci 323:3-10 PDF file
  16. Daugherty, A. and L.A. Cassis (2002) Mechanisms of arterial aneurysm formation. Curr Athero Reports. 4:222-227. PDF file
  17. Daugherty, A. and D.L. Rateri. (2002) T lymphocytes in atherosclerosis: The Yin-Yang of Th1 and Th2 influence on lesion formation. Circ Res. 90:1039-1040 PDF file
  18. Manning, M.W., L.A. Cassis, J. Huang, S.J. Szilvassy, and A. Daugherty (2002) Aortic aneurysms: Fresh insights from a novel animal model. Vasc Med. 7: 45-54. PDF file
  19. Daugherty, A. (2002). Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Curr Opin Lipid. 13: 453-455. 
  20. Daugherty, A., and L.A. Cassis. (2004) Mouse models of abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol. 24: 429-434. PDF file
  21. Daugherty, A. (2004) Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Curr Opin Lipid. 15: 93-95.
  22. Daugherty, A., and L.A. Cassis. (2004) Angiotensin II medicated development of vascular diseases. Trends in Cardiovasc Med. 14: 117-120. PDF file
  23. Daugherty, A., D.L. Rateri, and V.L. King. (2004) IL-5 links adaptive and natural immunity in reducing atherosclerotic disease. J Clin Invest. 114: 317-320. PDF file
  24. Daugherty, A., and L.A. Cassis. Angiotensin II and Abdominal aortic aneurysms. Current Hypertension Reports. Curr Hypertension Reports 2004, 6:442-446. PDF file
  25. Daugherty, A. (2005) Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Current Opinions in Lipidology. 16: 257-259.  PDF file
  26. Greenland, P., A. Daugherty, D. Harrington, J. Bennett, H. Roberts, and K.A. Taubert. (2005) The use of nonsterodial anti-inflammatory drugs (NSAIDS). A science advisory from the American Heart Association. Circulation. 111: 1713-1716.  PDF file
  27. Daugherty, A., and D. L. Rateri. (2005) Development of experimental designs for atherosclerosis studies in mice. Methods. 36: 129-138. PDF file
  28. Daugherty, A., N.R. Webb, D. L. Rateri, and V. L. King (2005) Cytokine regulation of macrophage function in atherogenesis. J. Lipid Res. 46: 1812-1822. PDF file
  29. Daugherty, A. and D.L. Rateri. (2006) Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Current Opinions in Lipidology. 17: 95-97.  PDF file
  30. Golledge, J., J. Muller, A. Daugherty, A. Van Rij, and P.E. Norman (2006).  Abdominal aortic aneurysms: Pathogenesis and implications for medical management. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2605-2613. (PMID 16973970)  PDF file

  31. Daugherty, A., D.L. Rateri, and L. A. Cassis. (2006) Role of the renin-angiotensin system in the development of abdominal aortic aneurysms in animals and humans. Annals of the New York Academy of Sciences. 1085: 82-91 (PMID 17182925)  PDF file

  32. Daugherty, A. and D.L. Rateri (2006) Atherosclerosis - Cell Biology and Lipoproteins - Commentary.  Current Opinions in Lipidology.
     
    17: 705-707. (PMID 17095917)  PDF file

  33. Antman, E.M., J.S. Bennett, A. Daugherty, C. Furberg, Harold Roberts, and K.A. Taubert. (2007)  American Heart Association Science Advisory on the use of nonsteroidal anti-inflammatory drugs (NSAIDS) - an update for clinicians. Circulation. 115: 1634-1642. (PMID 17325246)  PDF file

  34. Daugherty, A. and L.A. Cassis. (2007) Commentary on "Hackman et al, Angiotensin converting enzyme inhibitors and aortic rupture: a population-based case-control study. Lancet (2006):368; 659-665. Perspectives in Vascular Surgery and Endovascular Therapy. 19: 342-344. (PMID 17911572)  PDF file

  35. Lu, H, L.A. Cassis, and A. Daugherty. (2007) Atherosclerosis and Arterial Blood Pressure in mice.  Current Drug Targets 8: 1181-1189. (PMID 18045096)  PDF file

  36. Lu, H., L.A. Cassis, and A. Daugherty (2008) Renin-angiotensin system in vascular aneurysms formation. Current Hypertension Reports. 10: 99-106. (PMID 18474175)

  37. Rader, D.J. and A. Daugherty (2008). Atherosclerosis. Translating new discoveries into novel therapies. Nature. 451: 904-913. (PMID 18288179)  PDF file

  38. Daugherty, A. and D.L. Rateri. (2008) Atherosclerosis - Cell Biology and Lipoproteins - Commentary.  Current Opinions in Lipidology. 19: 328-329. (PMID 18460928)

  39. Daugherty, A., D.L. Rateri, and H. Lu. (2008) As macrophages indulge, atherosclerotic lesions bulge (Editorial). Circulation Research. 102: 1445-1447. (PMID 18566308)  PDF file

  40. Daugherty, A., H. Lu, D. L. Rateri, and L.A. Cassis. (2008). Augmentation of the renin angiotensinsystem by hypercholesterolemia promotes vascular diseases. Future Lipidol. 3: 625-636. (PMID 19802341) PDF File
  41. Macphee C.H. and A. Daugherty. (2008) Editorial: Cardiovascular diseases. Drug Discovery Today:Therapeutic Strategies. 5: 1-3.
  42. Daugherty, A., H. Lu, and D.L. Rateri. (2009). Atherosclerosis - Cell Biology and Lipoproteins -Commentary. Current Opinions in Lipidology. 20: 260-261. (PMID: 19433924).
  43. Lu. H, and A. Daugherty. (2009). Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Current Opinions in Lipidology. 20: 528-529 (PMID 19935204). PDF File

  44. Daugherty, A., D.L. Rateri, and H. Lu. (2010). S100A12 links to thoracic abdominal aortic aneurysms - Editorial. Circulation Research. 106: 13-15. (PMID 20056940). PDF File

  45. Daugherty, A., Lu, H., Howatt, D.A., and Rateri, D.L. (2009). Modes of defining atherosclerosis in mouse models: relative merits and evolving standards. Method Mol Biol. 2009;573:1-15. (PMID 19763919).

  46. Daugherty, A., X. Chen, A. Poduri, H. Lu, and L.A. Cassis. (2010). Genetic variants of the renin angiotensin system: effects on atherosclerosis in humans and experimental models. Current Atherosclerosis Reports. 12: 167-173. (PMID 20425255). PDF File

  47. Lu. H, and A. Daugherty. (2010). Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Current Opinions in Lipidology. 2012 Jun;23(3):263-4.(PMID:21206345)

  48. Lu. H, and A. Daugherty. (2011). Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Current Opinions in Lipidology. 2011 Aug;22(4):322-3. (PMID 21743310)

  49. Daugherty, A., L.A. Cassis, and H. Lu. (2011). Complex pathology of AngII-induced abdominal aortic aneurysms. Journal of Zhejiang University-SCIENCE B (Biomedicine and Biotechnology). 2011 Aug;12(8):624-8. (PMID 21796801)

  50. Bruemmer, D., A. Daugherty, H. Lu, and D. L. Rateri. (2011). Relevance of angiotensin II-induced aortic pathologies in mice to human aortic aneurysms. Annals of New York Academy of Science. 2011 Dec;1245:7-10. doi: 10.1111/j.1749-6632.2011.06332.x. (PMID 22211965)

  51. Wu, C., H. Lu, L.A. Cassis, and A. Daugherty. (2012). Molecular and pathophysiological features of angiotensinogen: a mini review. North American Journal of Medicine and Science. 2011 Oct 1;4(4):183-190. (PMID 22389749)

  52. 52. Lu. H, and A. Daugherty. (2012). Atherosclerosis - Cell Biology and Lipoproteins - Commentary. Current Opinions in Lipidology. 23: 263-264 (PMID 22576587)

  53. Daugherty, A. (2012). The New ATVB Editorial Team. Arteriosclerosis, Thrombosis, and Vascular Biology. 32:1545. (PMID ..)

  54. Lu, H., D. L. Rateri, Bruemmer, D., L.A. Cassis, and A. Daugherty. (2012). Involvement of the renin-angiotensin system in abdominal and thoracic aortic aneurysms. Clinical Science. 2012 Nov;123(9):531-43. (PMID 22788237)

  55. Daugherty, A. and D.L. Rateri. (2012). Do vivarium conditions influence atherosclerotic lesion size. Arteriosclerosis, Thrombosis, and Vascular Biology. 2012 Oct;32(10):2339-40. (PMID 22972938)

back to topNon Scientific Publications

  1. In memoriam: Stewart Charles Whitman (1964-2010).   Marcel Y, McBride H, Milne RW, Huff M, Daugherty A. J Lipid Res. 2010 Aug 10. PubMed PMID: 20699422.
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