<< backOutstanding Contributions to Cardiovascular Research - 2001

L. Henry Edmunds, M.D.

L. Henry Edmunds, M.D.

Julius Johnson Professor of Surgery
Department of Surgery, University of Pennsylvania


Selected Publications

  • Bowen FW, Hattori T, Narula N, Salgo IS, Plappert T, Sutton MG, Edmunds LH Jr. Reappearance of myocytes in ovine infarcts produced by six hours of complete ischemia followed by reperfusion. Ann Thorac Surg. 2001;71:1845-55.
  • Edmunds LH Jr. Evolution of prosthetic heart valves. Am Heart J. 2001;141:849-55.
  • Edmunds LH Jr. The quill passes. Ann Thorac Surg. 2000;70:1-2.
  • Rao AK, Sun L, Hiramatsu Y, Gorman JH 3rd, Edmunds LH Jr. Glycoprotein IIb/IIIa receptor antagonist tirofiban inhibits thrombin generation during cardiopulmonary bypass in baboons. Thromb Haemost. 1999;82:140-4.
  • Suzuki Y, Malekan R, Hanson CW 3rd, Niewiarowski S, Sun L, Rao AK, Edmunds LH Jr. Platelet anesthesia with nitric oxide with or without eptifibatide during cardiopulmonary bypass in baboons. J Thorac Cardiovasc Surg. 1999;117:987-93.
  • Kelley ST, Malekan R, Gorman JH 3rd, Jackson BM, Gorman RC, Suzuki Y, Plappert T, Bogen DK, Sutton MG, Edmunds LH Jr. Restraining infarct expansion preserves left ventricular geometry and function after acute anteroapical infarction. Circulation. 1999;99:135-42.
  • Edmunds LH Jr. Inflammatory response to cardiopulmonary bypass. Ann Thorac Surg. 1998;66:S12-6
  • Suzuki Y, Hillyer P, Miyamoto S, Niewiarowski S, Sun L, Rao AK, Hollenbach S, Edmunds LH Jr. Integrilin prevents prolonged bleeding times after cardiopulmonary bypass. Ann Thorac Surg. 1998;66:373-81.
  • Gorman JH 3rd, Jackson BM, Gorman RC, Kelley ST, Gikakis N, Edmunds LH Jr. Papillary muscle discoordination rather than increased annular area facilitates mitral regurgitation after acute posterior myocardial infarction. Circulation. 1997;96:II
  • Gikakis N, Khan MM, Hiramatsu Y, Gorman JH 3rd, Hack CE, Sun L, Rao AK, Niewiarowski S, Colman RW, Edmunds LH Jr. Effect of factor Xa inhibitors on thrombin formation and complement and neutrophil activation during in vitro extracorporeal circulation. Circulation. 1996;94:II341-6.
  • Chung JH, Gikakis N, Rao AK, Drake TA, Colman RW, Edmunds LH Jr. Pericardial blood activates the extrinsic coagulation pathway during clinical cardiopulmonary bypass. Circulation. 1996;93:2014-8.
  • Gorman RC, Ziats N, Rao AK, Gikakis N, Sun L, Khan MM, Stenach N, Sapatnekar S, Chouhan V, Gorman JH 3rd, Niewiarowski S, Colman RW, Anderson JM, Edmunds LH Jr. Surface-bound heparin fails to reduce thrombin formation during clinical cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1996;111:1-11
  • Bernabei A, Rao AK, Niewiarowski S, Colman RW, Sun L, Edmunds LH Jr. Recombinant desulfatohirudin as a substitute for heparin during cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1994;108:381-2.
  • Niewiarowski S, Edmunds LH Jr. Fibrinogen receptor antagonists in cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1993;106:931-3.
  • Shigeta O, Gluszko P, Downing SW, Lu W, Niewiarowski S, Edmunds LH Jr. Protection of platelets during long-term extracorporeal membrane oxygenation in sheep with a single dose of a disintegrin. Circulation. 1992;86:II398-404.
  • Musial J, Niewiarowski S, Rucinski B, Stewart GJ, Cook JJ, Williams JA, Edmunds LH Jr. Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms. Circulation. 1990;82:261-73.
  • Bavaria JE, Furukawa S, Kreiner G, Gupta KB, Streicher J, Edmunds LH Jr. Effect of circulatory assist devices on stunned myocardium. Ann Thorac Surg. 1990;49:123-8.
  • Karp RB, Mills N, Edmunds LH Jr. Coronary artery bypass grafting in the presence of valvular disease. Circulation. 1989;79:I182-4.
  • Edmunds LH Jr, Stephenson LW, Edie RN, Ratcliffe MB. Open-heart surgery in octogenarians. N Engl J Med. 1988;319:131-6.
  • Douglas PS, Hirshfeld JW Jr, Edmunds LH Jr. Clinical correlates of atrial tachyarrhythmias after valve replacement for aortic stenosis. Circulation. 1985;72:II159-63.
  • Edmunds LH Jr, Stephenson LW, Gadzik JP. The Blalock-Taussig anastomosis in infants younger than 1 week of age. Circulation. 1980;62:597-603.
  • Edmunds LH Jr, Wagner HR, Heymann MA. Aortic valvulotomy in neonates. Circulation. 1980;61:421-7.
  • Horowitz LN, Simson MB, Spear JF, Josephson ME, Moore EN, Alexander JA, Kastor JA, Edmunds LH Jr. The mechanism of apparent right bundle branch block after transatrial repair of tetralogy of Fallot. Circulation. 1979;59:1241-52.
  • Edmunds LH Jr, Saxena NC, Friedman S, Rashkind WJ, Dodd PF. Transatrial resection of the obstructed right ventricular infundibulum. Circulation. 1976;54:117-22.
  • Edmunds LH Jr, Gregory GA, Heymann MA, Kitterman JA, Rudolph AM, Tooley WH. Surgical closure of the ductus arteriosus in premature infants. Circulation. 1973;48:856-63.
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Comments: Darin Cecil | Last Modified: 11/04/2010
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