Phillip Bridges, Ph.D.
Assistant Professor
Department of Clinical Sciences
Ph.D., West Virginia University, 1999
M.S., University of Hawaii, 1995
B.Sc.Agr., University of Sydney, 1992
Contact Details:
College of Health Sciences
124C Charles T. Wethington Building
900 South Limestone St.
University of Kentucky
Lexington, KY 40536-0200
Ph: 859 323 1100 x 80844
Fax: 859 323 8957
Email: pbrid2@email.uky.edu
Publications:
Kim, B.G., M.D. Lindemann, P.J. Bridges and C. Ko. 2009. GEPRO: Gene
expression profiler for DNA microarray data.
Revista Colombiana de Ciencias Pecuarias.
In Press.
Fortune, J.E., E.L. Willis,
P.J.
Bridges
and C.S. Yang.
2009.
The periovulatory period in
cattle:
progesterone, prostaglandins,
oxytocin and ADAMTS proteases.
Animal Reproduction. 6:60-71.
2009.
Bridges, P.J.,
Y. Koo, D-W. Kang, S. Hudgins-Spivey, Z-J. Lan, X. Xu, F. DeMayo, A.
Cooney and C. Ko. 2008.
Generation of Cyp17iCre transgenic mice and their application to conditionally
delete estrogen receptor alpha (Esr1)
from the ovary and testis. Genesis. 46:499-505.
Na, G., P.J.
Bridges,
Y.
Koo and C. Ko. 2008.
Regulation of EDN2 gene expression in the mouse ovary:
Effect of hypoxia. Canadian Journal of Physiology and
Pharmacology. 86:310-319.
Ko, C., M.C. Gieske, S. Hudgins-Spivey,
P.J.
Bridges
and S. Lee. 2007.
Estrogen in female reproductive axis: Positive
estrogen feedback to pituitary.
Korean J. Reprod. Med. 34:207-213.
Al-Alem, L., P.J.
Bridges, W. Su, M.C. Gong, M. Iglarz and
C. Ko. 2007.
Endothelin-2 (EDN2) induces oviductal contraction via endothelin
receptor subtype A in rats. J.
Endocrinology. 193:383-391.
Bridges, P.J. and J.E. Fortune. 2007. Prostaglandins and ovulation in
cattle: Studies on production, transport and potential sites of receptor
binding. Mol. Cell. Endocrinol. 263:1-9.
Bridges, P.J., C.K. Komar and J.E. Fortune. 2006. Gonadotropin-induced
expression of mRNA for cyclooxygenase-2 (COX-2) and secretion of
prostaglandins E and F2a in bovine preovulatory follicles is regulated
by the progesterone receptor. Endocrinology. 147:4713-4722.
Bridges, P.J., M.A. Brusie and J.E. Fortune. 2005. Elevated temperature
(heat stress) in vitro reduces androstenedione and estradiol and
increases progesterone secretion by follicular cells from bovine
dominant follicles. Dom. Anim. Endocrinol. 29:508-522.
Bridges, P.J. and J.E. Fortune. 2003. Characteristics of developing
prolonged dominant follicles in cattle. Dom. Anim. Endocrinol.
25:199-214.
Madan, P., P.J. Bridges, C.M. Komar, A.G. Beristain, R. Rajamahendran,
J.E. Fortune and C.D. MacCalman. 2003. Expression of messenger RNA for
ADAMTS subtypes changes in the periovulatory follicle after the
gonadotropin surge and during luteal development and regression in
cattle. Biol. Reprod. 69:1506-1514.
Weems, Y.S., P.J. Bridges, R.G. Sasser, L. Ching, B.R. LeaMaster, D.L.
Vincent and C.W. Weems. 2002. Effect of mifepristone on pregnancy,
pregnancy specific protein B (PSPB), progesterone, estradiol-17b,
prostaglandin F2a (PGF2a) and prostaglandin E (PGE) in ovariectomized
90-day pregnant ewes. Prostaglandins and other Lipid Mediators.
70:195-208.
Kim, L., Y.S. Weems, P.J. Bridges, B.R. LeaMaster, D.L. Vincent and C.W.
Weems. 2001. Effects of indomethacin, luteinizing hormone (LH),
prostaglandin E2 (PGE2), trilostane, mifepristone, ethamoxytriphetol
(MER-25) on secretion of prostaglandin E (PGE), prostaglandin F2a
(PGF2a) and progesterone by ovine corpora lutea of pregnancy or the
estrous cycle. Prostaglandins and other Lipid Mediators. 63:189-203.
Knights, M., T.D. Maze, P.J. Bridges, P.E. Lewis, E.K. Inskeep. 2001.
Short-term treatment with a controlled internal drug releasing (CIDR)
device and FSH to induce fertile estrus and increase prolificacy in
anestrous ewes. Theriogenology. 55:1181-1191.
Weems, Y.S., P.J. Bridges, R.G. Sasser, B.R. LeaMaster, L. Ching and C.W.
Weems. 2001. Effect of the aromatase inhibitor CGS-16949A on pregnancy
and secretion of progesterone, estradiol-17b, prostaglandins E and F2a (PGE;
PGF2a) and pregnancy specific protein B (PSPB), in 90-day ovariectomized
pregnant ewes. Prostaglandins and other Lipid Mediators. 66:77-88.
Bridges, P.J., R. Taft, P.E. Lewis, W.R. Wagner and E.K. Inskeep. 2000.
Effect of the previously gravid uterine horn and postpartum interval on
follicular diameter and conception rate in beef cows treated with
estradiol benzoate and progesterone. J. Anim. Sci. 78:2172-2176.
Bridges, P.J., D.J. Wright, W.I. Buford, N. Ahmad, H. Hernandez-Fonseca,
M.L. McCormick, F.N. Schrick, R.A. Dailey, P.E. Lewis and E.K. Inskeep.
2000. Ability of induced corpora lutea to maintain pregnancy in beef
cows. J. Anim. Sci. 78:2942-2949.
Bridges, P.J., P.E. Lewis, W.R. Wagner and E.K. Inskeep. 1999.
Follicular dynamics, estrus and pregnancy after fixed time insemination
in beef cows treated with intravaginal progesterone inserts and
estradiol benzoate. Theriogenology. 52:573-583.
Bridges, P.J., Y.S. Weems, L.M. Kim, R.G. Sasser, B.R. LeaMaster, D.L.
Vincent and C.W. Weems. 1999. Effect of PGF2a, indomethacin, tamoxifen
or estradiol-17b on pregnancy, progesterone and pregnancy specific
protein B (PSPB) secretion in 88-90 day pregnant sheep. Prostaglandins
and other Lipid Mediators. 58:113-124.
Bridges, P.J., Y.S. Weems, L.M. Kim, B.R. LeaMaster, D.L. Vincent and
C.W. Weems. 1999. Effect of PGF2a, indomethacin, tamoxifen or
estradiol-17b on prostaglandin E (PGE), PGF2a and estradiol-17b
secretion in 88-90 day pregnant sheep. Prostaglandins and other Lipid
Mediators. 58:167-178.
Weems, Y.S., P.J. Bridges, B.R. LeaMaster, R.G. Sasser, D.L. Vincent and
C.W. Weems. 1999. Secretion of progesterone, estradiol-17b,
prostaglandins (PG) E (PGE), F2a (PGF2a) and pregnancy specific protein
B (PSPB) by 90 day intact and ovariectomized pregnant ewes.
Prostaglandins and other Lipid Mediators. 58:139-148.
Weems, Y.S., P.J. Bridges, B.R. LeaMaster, D.L. Vincent and C.W. Weems.
1999. Effect of trilostane on prostaglandins (PG) E and F2a (PGE;
PGF2a), estradiol-17b, and progesterone secretion and pregnancy of 90
day ovariectomized pregnant ewes. Prostaglandins and other Lipid
Mediators. 58:149-158.
Weems, Y.S., P.J. Bridges, Y. Tanaka, R.G. Sasser, B.R. LeaMaster, D.L.
Vincent and C.W. Weems. 1997. PGE1 or PGE2 not LH regulates secretion of
progesterone in vitro by the 88-90 day ovine corpus luteum of pregnancy.
Prostaglandins. 53:337-353.
Inskeep, E.K., P.E. Lewis, R.A. Dailey, P.J. Bridges, R.A. Taft and B.L.
Sayre. 1997. Follicular and luteal factors that affect embryonic
survival in the cow. Proc. 16th Ann. Conv. Am. Embryo Transfer Assn. p.
36-61.
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