| Douglas A. Andres | Regulation of Ras G-protein signaling. |
| Trevor Creamer | Structural and biophysical studies of calcineurin regulation |
| Robert Dickson | Signal transduction pathways and cellular processes that regulate aging and lifespan. |
| Rebecca E. Dutch | Mechanism of membrane fusion promoted by viral fusion proteins |
| Yvonne Fondufe-Mittendorf | Molecular mechanism of transcription regulation through studies on chromatin structure. |
| Mike Fried | The assembly of protein-DNA and protein-protein complexes that mediate DNA repair, transcription and blood clotting |
| Emilia Galperin | Functional cross-talk between endocytic and signaling cellular machineries and how this applies to cancer development. |
| Tianyan Gao | Regulation of PHLPP and its role in tumorigenesis |
| Matthew Gentry | Elucidating the role of phosphorylation and ubiquitination in neurodegenerative disease |
| Louis Hersh | Neuropeptidases - their role in Alzheimer's disease and diabetes. |
| Jianhang Jia | Hedgehog signaling and its role in cancer. |
| Konstantin V. Korotkov | Structural biology of ESX secretion system from pathogenic mycobacteria. |
| Harry LeVine | Relationship of protein misfolding to disease |
| Chunming Liu | Roles of Wnt/beta-catenin and JAK/STAT signaling in development, oncogenesis and stem cell self-renewal. |
| Michael Mendenhall | Cell division |
| Paul Murphy | Alzheimer's Disease Molecular Biology |
| Dan Noonan | Studying molecular mechanisms of steroid receptor-mediated gene expresion in carcinogenesis |
| Kathleen O'Connor | Integrin signaling in carcinoma cell motility and invasion |
| Sabire Ozcan | Glucose regulation of transport, metabolism and gene expression in diabetes |
| David Rodgers | Structural enzymology, protein engineering, and drug design |
| Kevin Sarge | Protein sumoylation, gene bookmarking, and their roles in human disease |
| Peter Spielmann | Structure of damaged DNA and its role in carcinogenesis; function of post-translational modification in signal transduction |
| Stefan Stamm | Mechanism of alternative splicing; Signal transduction pathways regulating alternative splicing; Alternative (mis)splicing and disease |
| Sam Turco | Glycobiology, Molecular Parasitology and Pathogenesis |
| Craig Vander Kooi | Cell Signaling & Tumor Angiogenesis |
| Charles Waechter | Mechanism of transbilayer movement of polar lipids in the rough endoplasmic reticulum; regulation of protein N-glycosylation |
| Qingjun Wang | Molecular mechanism of mammalian autophagy and its relevance to human diseases; neurodegeneration/cancer/aging; proteomics. |
| David Watt | Development of new synthetic methods, the synthesis of natural products and the development of photoactive analogs of natural products for elucidating receptor binding; and the synthesis of various drugs and natural products for studying interesting biological problems in collaboration with colleagues. |
| Sidney W. Whiteheart | Molecular mechanisms of exocytosis |
| Peter Zhou | Mechanisms of cancer cell metastasis. |
| Haining Zhu | Proteomics of Metal Ion Homeostasis and Neurodegenerative Disease |
