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LeVine Lab

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General Statement

            We seek to elucidate the contribution of misfolded proteins to chronic neurodegenerative diseases and to contribute to the development of therapeutic agents capable of modifying the course of these diseases. Our focus is on the Alzheimer’s β-peptide (Aβ) and its role in the cognitive decline in Alzheimer’s disease.

             As the average age of the populations of the developed nations continues to rise, the societal impact of chronic diseases with onset later in life increases. Multiple chronic neurodegenerative diseases, led in prevalence by Alzheimer’s disease (AD) and Parkinson’s disease, exact an escalating economic and personal toll on families and on society. By 2050, 14 million people in the U.S. will have AD and an additional 2 million will be stricken with Parkinson’s disease. http://www.alz.org/AboutAD/statistics.asp
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