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LeVine Lab Home | Research Summary | Projects | Translational Research | People | Recent Publications Translational Research Basic research into disease mechanisms can identify new therapeutic avenues that may have a significant impact on alleviating suffering. However, the path from an idea to a new medicine is complex and requires many different kinds of expertise and resources not found in a research laboratory. Translational research seeks practical application of that idea in directions foreign to most academic investigators. The chances of an idea alone being picked up and developed by industry are low. Investigators interested in practical applications must provide more than a concept or a patent to have it be considered. They must generate the specific kind of information needed by a drug discovery/development organization to evaluate the potential for successfully producing a drug that will make it into the clinic. This includes developing an appropriate intellectual property position in cooperation with the University. The P.I’s experience in the pharmaceutical industry and career commitment to finding effective therapeutics for Alzheimer’s disease and other chronic neurodegenerative diseases means that every discovery is considered for its possible medical applications, diagnostic or therapeutic. We are engaged in NIA/NIH-sponsored robotic screening of small molecule chemical compound libraries to identify inhibitors and modulators of Aβ42 oligomer formation. |
