BCH 611
Syllabus
Dr. Chi's Lectures
Lecture 1
Dr. Noonan's Lectures
Translation Lectures Lectures 1 & 2 Regulation of Translation Regulation of Translation 2 Translation Papers & Reviews Papers (2007) Dec. 4th Paper Micro RNA Binding Sites mTOR Structure NMD Review NMD Review 2 Virus Translation Control Review Papers (2006) Paper 1 Paper 2 Structure of translation Papers (2005) Translational Silencing of Ceruloplasmin Requires the Essential Elements of mRNA Circularization: Poly(A) Tail, Poly(A)- Binding Protein, and Eukaryotic Translation Initiation Factor 4G Inhibition of Translational Initiation by Let-7 MicroRNA in Human Cells Coupled Transcription and Translation Within Nuclei of Mammalian Cells Nuclear protein synthesis: Are-evaluation eEF1A binding to aminoacylated viral RNA represses minus strand synthesis by TYMVRNA-dependent RNA polymerase Translational Regulation of Terminal Oligopyrimidinem RNAs Induced by Serumand Amino Acids Involves Distinct Signaling Events Review Articles (2006) Bac initiation rev Micro RNA review 1 Micro RNA review 2 Micro RNAs & Viruses Micro RNAs in plants rev 1 Micro RNAs in plants rev 2 mTOR review 1 mTOR review 2 RNA Editing Review Review Articles (2005) New perspectives on connecting messenger RNA3’ end formation to transcription The translation elongation factor 1A in tumorigenesis, signal transduction and apoptosis: Review article Ribo-gnome: The Big World of Small RNAs Binding proteins form RNA localization and local translation, and their dysfunction in genetic neurological disease Structural and functional features of eukaryotic mRNA untranslated regions Post-Transcriptional Regulation of Gene Expression by Degradation of Messenger RNAs Up stream and down stream of mTOR mTOR-mediated regulation of translation factors by amino acids FUNCTIONS OF THE 30-UNTRANSLATED REGIONS OF POSITIVE STRAND RNA VIRAL GENOMES Small RNA asymmetry in RNAi: Function in RISC assembly and gene regulation Synthesis of the Translational apparatus is regulated at the translational level Transcriptional silencing and translational control: key features of early germline development Regulation of mRNA translation by 5’- and 3’-UTR-binding factors THE POWER OF THE 3′ UTR:TRANSLATIONAL CONTROL AND DEVELOPMENT The role of mRNA 5'-noncoding and 3'-end sequences on 40S ribosomal subunit recruitment, and how RNA viruses successfully compete with cellularm RNAs to ensure their own protein synthesis Amino Acids as Regulators of Gene Expression at the Level of mRNA Translation MOLECULAR MECHANISMS OF TRANSLATIONAL CONTROL I MOLECULAR MECHANISMS OF TRANSLATIONAL CONTROL II Post-transcriptional regulation in cancer THE MOLECULAR MECHANICS OF EUKARYOTIC TRANSLATION
Translation Lectures
Lectures 1 & 2 Regulation of Translation Regulation of Translation 2
Lectures 1 & 2
Regulation of Translation
Regulation of Translation 2
Translation Papers & Reviews
Papers (2007) Dec. 4th Paper Micro RNA Binding Sites mTOR Structure NMD Review NMD Review 2 Virus Translation Control Review Papers (2006) Paper 1 Paper 2 Structure of translation Papers (2005) Translational Silencing of Ceruloplasmin Requires the Essential Elements of mRNA Circularization: Poly(A) Tail, Poly(A)- Binding Protein, and Eukaryotic Translation Initiation Factor 4G Inhibition of Translational Initiation by Let-7 MicroRNA in Human Cells Coupled Transcription and Translation Within Nuclei of Mammalian Cells Nuclear protein synthesis: Are-evaluation eEF1A binding to aminoacylated viral RNA represses minus strand synthesis by TYMVRNA-dependent RNA polymerase Translational Regulation of Terminal Oligopyrimidinem RNAs Induced by Serumand Amino Acids Involves Distinct Signaling Events Review Articles (2006) Bac initiation rev Micro RNA review 1 Micro RNA review 2 Micro RNAs & Viruses Micro RNAs in plants rev 1 Micro RNAs in plants rev 2 mTOR review 1 mTOR review 2 RNA Editing Review Review Articles (2005) New perspectives on connecting messenger RNA3’ end formation to transcription The translation elongation factor 1A in tumorigenesis, signal transduction and apoptosis: Review article Ribo-gnome: The Big World of Small RNAs Binding proteins form RNA localization and local translation, and their dysfunction in genetic neurological disease Structural and functional features of eukaryotic mRNA untranslated regions Post-Transcriptional Regulation of Gene Expression by Degradation of Messenger RNAs Up stream and down stream of mTOR mTOR-mediated regulation of translation factors by amino acids FUNCTIONS OF THE 30-UNTRANSLATED REGIONS OF POSITIVE STRAND RNA VIRAL GENOMES Small RNA asymmetry in RNAi: Function in RISC assembly and gene regulation Synthesis of the Translational apparatus is regulated at the translational level Transcriptional silencing and translational control: key features of early germline development Regulation of mRNA translation by 5’- and 3’-UTR-binding factors THE POWER OF THE 3′ UTR:TRANSLATIONAL CONTROL AND DEVELOPMENT The role of mRNA 5'-noncoding and 3'-end sequences on 40S ribosomal subunit recruitment, and how RNA viruses successfully compete with cellularm RNAs to ensure their own protein synthesis Amino Acids as Regulators of Gene Expression at the Level of mRNA Translation MOLECULAR MECHANISMS OF TRANSLATIONAL CONTROL I MOLECULAR MECHANISMS OF TRANSLATIONAL CONTROL II Post-transcriptional regulation in cancer THE MOLECULAR MECHANICS OF EUKARYOTIC TRANSLATION
Papers (2007)
Dec. 4th Paper Micro RNA Binding Sites mTOR Structure NMD Review NMD Review 2 Virus Translation Control Review
Dec. 4th Paper
Micro RNA Binding Sites
mTOR Structure
NMD Review
NMD Review 2
Virus Translation Control Review
Papers (2006)
Paper 1 Paper 2 Structure of translation
Paper 1
Paper 2
Structure of translation
Papers (2005)
Translational Silencing of Ceruloplasmin Requires the Essential Elements of mRNA Circularization: Poly(A) Tail, Poly(A)- Binding Protein, and Eukaryotic Translation Initiation Factor 4G Inhibition of Translational Initiation by Let-7 MicroRNA in Human Cells Coupled Transcription and Translation Within Nuclei of Mammalian Cells Nuclear protein synthesis: Are-evaluation eEF1A binding to aminoacylated viral RNA represses minus strand synthesis by TYMVRNA-dependent RNA polymerase Translational Regulation of Terminal Oligopyrimidinem RNAs Induced by Serumand Amino Acids Involves Distinct Signaling Events
Translational Silencing of Ceruloplasmin Requires the Essential Elements of mRNA Circularization: Poly(A) Tail, Poly(A)- Binding Protein, and Eukaryotic Translation Initiation Factor 4G
Inhibition of Translational Initiation by Let-7 MicroRNA in Human Cells
Coupled Transcription and Translation Within Nuclei of Mammalian Cells
Nuclear protein synthesis: Are-evaluation
eEF1A binding to aminoacylated viral RNA represses minus strand synthesis by TYMVRNA-dependent RNA polymerase
Translational Regulation of Terminal Oligopyrimidinem RNAs Induced by Serumand Amino Acids Involves Distinct Signaling Events
Review Articles (2006)
Bac initiation rev Micro RNA review 1 Micro RNA review 2 Micro RNAs & Viruses Micro RNAs in plants rev 1 Micro RNAs in plants rev 2 mTOR review 1 mTOR review 2 RNA Editing Review
Bac initiation rev
Micro RNA review 1
Micro RNA review 2
Micro RNAs & Viruses
Micro RNAs in plants rev 1
Micro RNAs in plants rev 2
mTOR review 1
mTOR review 2
RNA Editing Review
Review Articles (2005)
New perspectives on connecting messenger RNA3’ end formation to transcription The translation elongation factor 1A in tumorigenesis, signal transduction and apoptosis: Review article Ribo-gnome: The Big World of Small RNAs Binding proteins form RNA localization and local translation, and their dysfunction in genetic neurological disease Structural and functional features of eukaryotic mRNA untranslated regions Post-Transcriptional Regulation of Gene Expression by Degradation of Messenger RNAs Up stream and down stream of mTOR mTOR-mediated regulation of translation factors by amino acids FUNCTIONS OF THE 30-UNTRANSLATED REGIONS OF POSITIVE STRAND RNA VIRAL GENOMES Small RNA asymmetry in RNAi: Function in RISC assembly and gene regulation Synthesis of the Translational apparatus is regulated at the translational level Transcriptional silencing and translational control: key features of early germline development Regulation of mRNA translation by 5’- and 3’-UTR-binding factors THE POWER OF THE 3′ UTR:TRANSLATIONAL CONTROL AND DEVELOPMENT The role of mRNA 5'-noncoding and 3'-end sequences on 40S ribosomal subunit recruitment, and how RNA viruses successfully compete with cellularm RNAs to ensure their own protein synthesis Amino Acids as Regulators of Gene Expression at the Level of mRNA Translation MOLECULAR MECHANISMS OF TRANSLATIONAL CONTROL I MOLECULAR MECHANISMS OF TRANSLATIONAL CONTROL II Post-transcriptional regulation in cancer THE MOLECULAR MECHANICS OF EUKARYOTIC TRANSLATION
New perspectives on connecting messenger RNA3’ end formation to transcription
The translation elongation factor 1A in tumorigenesis, signal transduction and apoptosis: Review article
Ribo-gnome: The Big World of Small RNAs
Binding proteins form RNA localization and local translation, and their dysfunction in genetic neurological disease
Structural and functional features of eukaryotic mRNA untranslated regions
Post-Transcriptional Regulation of Gene Expression by Degradation of Messenger RNAs
Up stream and down stream of mTOR
mTOR-mediated regulation of translation factors by amino acids FUNCTIONS OF THE 30-UNTRANSLATED REGIONS OF POSITIVE STRAND RNA VIRAL GENOMES
Small RNA asymmetry in RNAi: Function in RISC assembly and gene regulation
Synthesis of the Translational apparatus is regulated at the translational level
Transcriptional silencing and translational control: key features of early germline development
Regulation of mRNA translation by 5’- and 3’-UTR-binding factors
THE POWER OF THE 3′ UTR:TRANSLATIONAL CONTROL AND DEVELOPMENT
The role of mRNA 5'-noncoding and 3'-end sequences on 40S ribosomal subunit recruitment, and how RNA viruses successfully compete with cellularm RNAs to ensure their own protein synthesis
Amino Acids as Regulators of Gene Expression at the Level of mRNA Translation
MOLECULAR MECHANISMS OF TRANSLATIONAL CONTROL I
MOLECULAR MECHANISMS OF TRANSLATIONAL CONTROL II
Post-transcriptional regulation in cancer
THE MOLECULAR MECHANICS OF EUKARYOTIC TRANSLATION
Transcription Lecture Lecture 1 Lecture 2Lecture 3 Transcription Reviews Mechanisms of ATP dependent chromatin remodeling (added Oct. 11, 2007) Chromatin Remodelling Review Transcription Elongation Reviews Transcription Initiation Reviews Transcription Termination Reviews Chromatin Remod Rev-06 Coregulator Rev-06 Med Comlex review-05 Plant elongation Rev Rho Termination Rev-06 Sigma Factor Rev-05 Steric term paper Steric-Torpedo Term paper TATA site rev-06 Torpedo term paper
Transcription Lecture
Lecture 1 Lecture 2Lecture 3
Transcription Reviews
Mechanisms of ATP dependent chromatin remodeling (added Oct. 11, 2007) Chromatin Remodelling Review Transcription Elongation Reviews Transcription Initiation Reviews Transcription Termination Reviews Chromatin Remod Rev-06 Coregulator Rev-06 Med Comlex review-05 Plant elongation Rev Rho Termination Rev-06 Sigma Factor Rev-05 Steric term paper Steric-Torpedo Term paper TATA site rev-06 Torpedo term paper
Dr. Wong
Lecture Notes PPT for 9/13/07 PPT for 9-18 PPT for 9-20 PPT for 9-25 Switching human telomerase on and off with hpot1 Telomerase maintains telomere structures in normal human cells
Lecture Notes
PPT for 9/13/07 PPT for 9-18 PPT for 9-20 PPT for 9-25 Switching human telomerase on and off with hpot1 Telomerase maintains telomere structures in normal human cells
PPT for 9/13/07
PPT for 9-18
PPT for 9-20
PPT for 9-25
Switching human telomerase on and off with hpot1
Telomerase maintains telomere structures in normal human cells
Dr. Rodgers
Lecture Notes DNA Part 1 | RNA Part 2 | REP Part 3 Reviews Beveridge | Butcher | Cunningham | Ghosh | Leontis | Neidle | Patel | Sherratt | Sosnick | Travers
DNA Part 1 | RNA Part 2 | REP Part 3
Reviews
Beveridge | Butcher | Cunningham | Ghosh | Leontis | Neidle | Patel | Sherratt | Sosnick | Travers
Dr. Wilkerson
8-28-07 Lecture Presentation (PPT) | Supplement Bioch (PPT) NRO | Microarray | Buckler Paper | Microarray (Ericklander) chIP Cloning | Footprinting (Galas& Schmitz) Footprinting (Kang) | NRO (Li Chaikof) 8-30-07 Lecture Presentation (PPT) Bacterial Expression I | Bacterial Expression II | Baculovirus Mammalian | Protein Expression | Proteomics I | Proteomics II | RNAi I | RNAi II SNP I | SNP II
8-28-07
Lecture Presentation (PPT) | Supplement Bioch (PPT) NRO | Microarray | Buckler Paper | Microarray (Ericklander) chIP Cloning | Footprinting (Galas& Schmitz) Footprinting (Kang) | NRO (Li Chaikof)
Lecture Presentation (PPT) | Supplement Bioch (PPT)
NRO | Microarray | Buckler Paper | Microarray (Ericklander) chIP Cloning | Footprinting (Galas& Schmitz) Footprinting (Kang) | NRO (Li Chaikof)
8-30-07
Lecture Presentation (PPT) Bacterial Expression I | Bacterial Expression II | Baculovirus Mammalian | Protein Expression | Proteomics I | Proteomics II | RNAi I | RNAi II SNP I | SNP II
Lecture Presentation (PPT)
Bacterial Expression I | Bacterial Expression II | Baculovirus
Mammalian | Protein Expression |
Proteomics I | Proteomics II | RNAi I | RNAi II
SNP I | SNP II
Dr. Young-In Chi's Lectures
Guo-Min Li's Lectures
Student presentation journal articles for Dr. Guo-Min Li's class
