UK Home Academics Athletics Medical Center Research Site Index Search UK
A researcher at work in the lab UK College of Medicine Department Logo filler image to complete the header
click here to view a link
UK COBRE: Investigators


Center of Biomedical Research Excellence in the Molecular Basis of Human Disease

National Institutes of Health, Center of Biomedical Research Excellence (COBRE)

COBRE Homepage | COBRE Pilot Grant Program | Forms | Internal Advisory Board |
External Advisory Board | Investigators
| Announcements | Cores | Grant Submission Information | Meetings | New Publications | Data Sharing

Current Research Investigators, 2009 2010

 

Center of Biomedical Research Excellence in the Molecular Basis of Human Disease;  National Institutes of Health, Center of Biomedical Reserach Excellence

Dr. Craig Vander Kooi
Structural Studies of Neuropilin Signaling

Our ultimate goal is to define the fundamental mechanism(s) of neuropilin activity in activation of downstream signaling cascades.
Read more about this project
View Dr. Vander Kooi's faculty web page

Dr. Matthew Gentry
Deciphering the Connection between Lafora Disease and AMP-activated Protein Kinase/Wolff-Parkinson-White Syndrome

The long-term objective of this project is to define the relationship between the phosphatase laforin and AMP-activated protein kinase (AMPK) in two human diseases.
Read more about this project
View Dr. Gentry's faculty web page

Dr. Christian Paumi
Negative Regulation of the Yeast MRP, Ycf1p, and Human MRPs by CKII

In the current study we will determine the role of CKII in regulating the cellular function of the MRPs. Ultimately our goal is to define the role of CKII in the regulation of the human MRPs, MRPI and MRP6. The results of this study will provide valuable insights into how MRP function is regulated in vivo and will reveal new therapeutic targets for the treatment
of MRPI-associated cancers and MRP6-dependent PXE.
Read more about this project
View Dr. Paumi's faculty web page

Dr. Francesc Marti
Mechanisms of Peripheral Regulatory T Cell Generation: Role of Polyunsaturated Fatty Acids

The main goal of the project is to uncover the molecular mechanisms by which PUFAs regulate the T cell response and, specifically, the generation of suppressor ITreg.
Read more about this project
View Dr. Marti's faculty web page

Dr. Qingjun Wang
Molecular Mechanism of Mammalian Autophagy

The long-term goal of this project is to understand the molecular mechanism of autophagy in mammals and its relevance to human diseases, utilizing integrated approaches including mouse genetics, mass spectrometry-based proteomics and cell biology.
Read more about this project
View Dr. Wang's faculty web page

 

Current Pilot Investigators, 2009 2010

 

Dr. Jason Johnston
Identification of QshBC-regulated genes in nontypeable Haemophilus influenzae

The specific aim of this project is to identify genes that are regulated by the QshABC system in NTHi and characterize the regulation.
Read more about this project
View Dr. Johnston's faculty web page

 


.

Search COM
 
Comments to fish@uky.edu, Last Modified: Thursday, September 03, 2009
Copyright © 2004, University of Kentucky Chandler Medical Center
Terms, Conditions & Privacy Statement
An Equal Opportunity University