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Behavioral Science

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Photo of Thomas KellyThomas H. Kelly, Ph.D.

(University of Minnesota, 1983)

134 Medical Behavioral Science Building
Phone: (859) 323-5206
e-mail: thkelly@uky.edu

Research Description

Thomas H. Kelly, Ph.D., is the Robert Straus Professor and Vice-Chair of the Department of Behavioral Science in the College of Medicine; Professor of Psychiatry and Psychology, Director of Research Education, Training and Career Development for the Center for Clinical and Translational Science; and a member of the Center for Drug Abuse Research. Dr. Kelly is a clinical behavioral pharmacologist with over 20 years of research and training experience in the experimental analysis of drug-behavior interactions with an emphasis on individual differences in drug abuse vulnerability.  He is the Scientific Director for the NIDA-supported Center for Drug Abuse Research Translation and PI of Center Project 2, entitled ‘Drug Abuse Liability and Sensation-Seeking Status,’ which examines individual differences drug abuse vulnerability.  In the University of Kentucky Center for Biomedical Excellence in Women’s Health (funded by the National Institute on Research Resources), Dr. Kelly is PI of Project 5, entitled ‘Actions of Estradiol and Progesterone on Behavior,’ which examines the neuropharmacological effects of HPG hormones.  He also serves as co-I on multiple drug abuse research and training grants and has served on numerous extramural study sections. He has served on over 25 graduate dissertation committees and has supervised 2 PhD postdoctoral scholars, and 2 MD and 2 PhD junior faculty members supported by NIH career development awards.  He is also a member of the University of Kentucky Institutional Review Board.

2012 Accomplishments

Dr. Thomas H. Kelly is the Robert Straus Professor and Vice-Chair of the Department of Behavioral Science in the College of Medicine; Professor of Psychiatry and Psychology, and a faculty affiliate of the Center for Drug Abuse Research. He supports the College of Nursing as Associate Dean for Research and the Center for Clinical and Translational Science as Director of Research Education, Training and Career Development.  During the previous year, he served in multiple educational roles, including mentoring and teaching in medical and graduate courses, updating a Clinical and Translational Training Module for ICM II and supporting certificate, MS and PhD programs in Clinical and Translational Science.  His service activities locally include participation on the UK Senate Research Committee, IRB, the Center for Clinical and Translational Science Scientific Advisory Committee, the ICM Sequence Oversight Committee, the COM Education Strategic Planning Committee and the Academic Advisory Panel for the Tobacco Policy Research Program and nationally include regular and ad-hoc NIH and AIBS study section membership. Mentoring activities include support of the successful transition of an early career faculty mentee from K01 to K02 support and oversight of 1 PhD student and 3 undergraduates.  Dr. Kelly is a clinical behavioral pharmacologist examining drug-behavior interactions and assessing bio-behavioral factors associated with individual differences in drug abuse vulnerability. His current research combines clinical pharmacological and neuroimaging methodologies to examine the role of HPG hormones and neurobiologically-based personality dimensions on vulnerability to drug abuse.  He is currently the PI of one project and serves as the Scientific Director of the NIDA-funded Center for Drug Abuse Research Translation (CDART), is Director of Director of Research Education, Training and Career Development for the NCRR-funded CCTS and is co-I on 1 NIDA award and is the Faculty Mentor for a NIDA F31 award. During the past year he has contributed to 8 peer-reviewed manuscripts, 1 book chapter and multiple grant applications.

Research Funding

National Institute on Drug Abuse, Drug Abuse Liability and Sensation-Seeking Status, 1998 – 2012

National Institute of Research Resources, Actions of Estradiol and Progesterone on Behavior, 2000 – 2010

National Institute on Drug Abuse, Separate and Combined Effects of Progesterone and Triazolam in Healthy Women, 2007 – 2009

Representative Publications

Babalonis, S., Emurian, C., Martin, C.A., Lile, J.A. and Kelly. T.H. Modulation of the discriminative stimulus effects of triazolam across the menstrual cycle phase in healthy pre-menopausal women.  Drug and Alcohol Dependence, in press.

Kelly, T.H., Robbins, G., Martin, C.A., Fillmore, M.T., Lane, S.D., Harrington, N.G. and Rush, C.R.  Individual Differences in Drug Abuse Vulnerability: d-Amphetamine and Sensation-Seeking Status.  Psychopharmacology, 189: 17-25, 2006.

Kelly, T.H., Taylor, R.C., Heishman, S.J. and Howland, J.  Performance-based assessment of behavioral impairment in occupational settings.  In: Karch, S.B., Peat, M. and Forrest, R. (eds.) Handbook on Drug Abuse, Volume II, CRC Press, Boca Raton, pp. 238-266, 2007. 

Lile, J.A., Kendall, S.L., Babalonis, S., Martin, C.A., and Kelly. T.H. Evaluation of estradiol administration on the discriminative-stimulus and subject-rated effects of d-amphetamine in healthy pre-menopausal women. Pharmacology, Biochemistry and Behavior, 87: 258-266, 2007.

Makris, A.P., Rush, C.R., Frederich, R.C., Taylor, A.C., and Kelly, T.H. Behavioral and subjective effects of d-amphetamine and modafinil in healthy adults. Experimental and Clinical Psychopharmacology, 15: 123-133, 2007.

Martin, C.A., Guenthner, G., Bingcang, C., Rayens  M.K. and Kelly, T.H. A Pilot Study: Attention Deficit Hyperactivity Disorder, Measurement of the subjective effects of methylphenidate in ADHD 11-15 year olds. Journal of Child and Adolescent Psychopharmacology, 17: 63-73, 2007.

Okoli, C.T.C., Kelly, T.H. & Hahn, E.L. Secondhand Smoke and Nicotine Exposure: A Brief Review. Addictive Behaviors, 32: 1977-1988, 2007.

Martin, S.; Covell, J.; Joseph, J.; Chebrolu, H.; Smith, C.; Kelly, T.; Jiang; Y. & Gold, B.T. Human experience seeking correlates with hippocampus volume: Convergent evidence from manual tracing and Voxel-Based Morphometry. Neuropsychologia, 45: 2874-2881, 2007.

Stoops, W.W., Lile, J.A., Robbins, G., Martin, C.A., Rush, C.R. and Kelly, T.H. The Reinforcing, Subject-Rated, Performance, and Cardiovascular Effects of d-Amphetamine: Influence of Sensation-Seeking Status.  Addictive Behaviors, 32: 1177-1188, 2007.

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