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Allison Caban-Holt, Ph.D.
(University of Tennessee, Knoxville (2004), Concentration: Clinical Psychology)
Allison Caban-Holt, Ph.D., Assistant Professor
Dr. Caban-Holt’s research focuses on cognition, the behavioral effects of dementia, and detecting dementia through neuropsychological evaluation. Her research experience is quite varied; working on projects such as looking at sleep and agitation in dementia patients, investigating the potential protective effects of Vitamin E and selenium for the prevention of Alzheimer’s disease, and elucidating the challenges for African-American caregivers of dementia patients. Dr. Caban-Holt will be UK site investigator for an Alzheimer’s Disease Cooperative Study-sponsored clinical trial looking at home-based, self-administered assessment methods for identifying cognitive decline in health individuals over the age of 75.
Allison Caban-Holt, Ph. D. is a co-investigator on a grant entitled “Aging of Frontal Structure and Function in Down Syndrome and Dementia”. Work on this 5-year grant award has expanded Dr. Caban-Holt’s area of expertise in neuropsychological measurement in dementia to include patients with Down Syndrome. In the past year, the project has continued with steady enrollment and presented a symposium in Louisville, KY entitled “Adults with Down Syndrome: Applying Research Findings to Health Brain Aging”. Dr. Caban-Holt completed collection of pilot data from a grant awarded from the Department of Behavioral Science to study prescription drug misuse in a low-income, elderly community sample. Dr. Caban-Holt will collaborate with Dr. Larry Figgs in the College of Public Health to combine this pilot data with health department data to further examine stress and health in these study participants. Initial data analyses have been conducted. She continues as the Protocol Investigator for a multi-site clinical trial sponsored by the Alzheimer’s Disease Cooperative Study looking at home-based assessment measures for detecting changes in cognition in adults over the age of 75. Her study site has maintained over 80% retention of participants over the course of the first 36 months of the 48-month long investigation. She also continues as a co-investigator of the PREADVISE clinical trial which is currently conducting telephone follow-up of over 4,200 men in the U.S. and Canada to determine whether vitamin E and Selenium alone or in combination will reduce the incidence of Alzheimer’s disease. She presented findings from the investigation at the Society for clinical Trials annual meeting in Miami, FL (May, 2012). Dr. Caban-Holt was first-author of a manuscript based on PREADViSE normative data on the Ruff 2&7 Test in older males, and co-authored 3 additional manuscripts in 2012.
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