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Barnstable Brown Kentucky Diabetes and Obesity Center

BBDOC

BARNSTABLE BROWN OBESITY AND DIABETES RESEARCH DAY


Olivier Thibault, Ph.D.

Picture of Dr. Thibault   
   


          Associate Professor, Department of Molecular and Biomedical Pharmacology




Contact Information

Training and Publications

University of Kentucky
MS-320 Wm. R. Willard Medical Education Building Publication Listing on PubMed
800 Rose Street
Lexington, KY 40536-0298  
Telephone: (859) 323-4863  
Fax: (859) 323-1981  
 

Research Interests

Dr. Thibault's studies analyze brain mechanisms altered in animal models displaying characteristics of metabolic syndrome, which may include hyperinsulinemia, hyperglycemia, dyslipidemia, diabetes and/or obesity. The majority of studies of metabolic syndrome rarely investigate effects on brain function during aging. However, it is increasingly apparent that peripheral metabolic conditions can affect aging processes in general, and the course of brain aging in particular. Our interests, therefore, are in identifying the underlying mechanisms through which individual components of peripheral metabolic syndrome impact brain function by focusing on Ca2+-sensitive biomarkers known to be modified in aging. To this end, the laboratory is working on modifying a glucose imaging technique to be applied for the first time to studies in the aging hippocampus. Ultimately, this project is aimed at identifying novel therapeutic targets that may contribute to prevention of cognitive decline with aging.

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Page last updated Wednesday, May 08, 2013