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Barnstable Brown Kentucky Diabetes and Obesity Center



Hollie Swanson, Ph.D.

Picture of Dr. Swanson   

          Professor, Department of Molecular and Biomedical Pharmacology

Contact Information

Training and Publications

University of Kentucky Research Summary (PDF)
MN-322 Wm. R. Willard Medical Ed. Building Publication Listing on PubMed
800 Rose Street
Lexington, KY 40536-0298  
Telephone: (859) 323-1463  
Fax: (859) 323-1981  

Research Interests

Dr. Swanson is engaged in basic research related to drug metabolism, environmental toxicology, obesity and cancer. Her current studies are focused on developing novel antagonists of the aryl hydrocarbon receptor (AHR). The AHR is a ligand activated nuclear receptor that regulates the expression of drug metabolizing enzymes and mediates the carcinogenic actions of a number of environmental contaminants. Increasing evidence indicates that the AHR also plays important roles in inflammation and human diseases such as obesity, metabolic syndrome and diabetes. A major goal of Dr. Swanson’s work are to utilize AHR agonists and antagonists as well as additional molecular and in vivo approaches to establish the role of the AHR in these chronic disease states. An additional goal is to determine whether these AHR agonists and antagonists can be effectively used to treat obesity, metabolic syndrome and diabetes.

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Page last updated Monday, December 14, 2009