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Barnstable Brown Kentucky Diabetes and Obesity Center



Gerald Supinski, M.D.

Vice Chair Research, Department of Pulmonary, Critical Care, and Sleep Medicine

Contact Information

Training and Publications

University of Kentucky
Room K528 Kentucky Clinic Publication Listing on PubMed
740 South Limestone
Lexington, KY 40536-0284  
Telephone: (859) 323-5045  
Fax: (859) 257-2418  

Research Interests

Dr. Supinski's laboratory focuses on two areas of research: (a) respiratory muscle dysfunction in critically ill patients, and (b) the mechanisms of organ failure and death from sepsis. Both topics are related to critical care medicine. The goal of their study of respiratory muscle dysfunction is to discover new treatments designed to improve weaning patients from mechanical ventilation, thereby reducing patient morbidity. The goal of their study of sepsis is to discover new treatments to prevent multiorgan failure, the leading cause of death in intensive care units in the United States. They use animal models of disease to establish disease mechanisms and to trial new therapies and they also study human patients in the ICU to allow them to translate basic science discoveries into clinical therapies. Dr. Supinski's laboratory uses a mixture of techniques to accomplish these objectives, including proteomic assessments, physiological assessment of organ and cell function, biochemical assessment of enzyme pathways, cell culturing techniques, fluorescent microscopy, molecular techniques to alter gene expression, assessment of organ function in critically ill patients (muscle cardiac, vascular, lung), and muscle biopsy techniques in patients.

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Page last updated Monday, August 01, 2011