News
July'08 Manisha Gupte's research will test the hypothesis that dysregulated ACE2 in adipose tissue contributes to the development of obesity-related hypertension. Moreover, she hypothesizes that fatty acids are the mechanistic mediators of obesity-induced regulation of adipocyte ACE2. In Aim 1, we will define effects of ACE2 deficiency in mice on the development of obesity and obesity-hypertension. In Aim 2. we will determine the effects of specific fatty acids on the expression of ACE2 mRNA, protein and activity in 3T3-L1 adipocytes. Results from these studies will identify novel mechanisms contributing to the development of obesity and obesity-hypertension.
Yue Zhao will study the role of the neuron-derived ophan receptor 1 (NOR1) in endothelial
cell activation, monocyte chemoattractant protein-1 (MCP-1) expression and monocyte recruitment during atherogenesis. Preliminary data indicate that NOR1 regulates MCP-1 expression in response to pro-inflammatory stimuli. It is hypothesized that transcriptional induction of NOR-1 expression during endothelial cell activation is required for MCP-1 expression and monocyte recruitment during atherogenesis. To test this hypothesis, in
Aim 1, it is proposed to determine the transcription regulation of NOR-1 expression during endothelial activation. In Aim 2, the mechanisms involved in MCP-1 by NOR-1 will be studied, as well as the role of NOR-1 in moncyte recruitment.
November' 07 The Graduate Center for Nutritional Sciences was recognized as one of the top ten nutrition programs in the Country in the Faculty Scholarly Productivity Index by Academic Analytics.
August' 07 Dr. Jianhua Shao, MD, PhD, Assistant Professor, Nutritional Sciences, receives the 2007 Thomas Lee Career Development Award from the American Diabetes Association (ADA). This award is given from the ADA to applicants who receive the best reviewer score on their application.
July' 07 The GCNS relocated administratively to the College of Medicine (COM) where it continues to act as a multidisciplinary unit in graduate education and research. To coordinate graduate education with the COM, the GCNS joined the Integrative Biomedical Sciences (IBS) Program and will also continue to admit students directly into the Nutritional Sciences, allowing us to maintain a multidisciplinary education focus, and to serve the educational needs of faculty in nutrition-related units outside of Medicine, such as Agriculture, Health Sciences, Pharmacy and Nursing.
October '06 Manisha Gupte, M.S., a graduate student working with Dr.Lisa Cassis in theGraduate Center for Nutritional Sciences, was the first place winner in the student category of the Gill Heart Institute Poster Session for 2006. Manisha presented results from research demonstrating novel expression of the ACE2 enzyme in adipose tissue, and regulation of the enzyme in mice with diet-induced obesity.
September '06 Dr.Bernhard Hennig has received the 2006 Helen LeBaron Hilton Award from I
owa State University for Outstanding Leadership and Distinguished Achievements. He made two invited talks entitled: "Impact of nutrition on PCB toxicity" at the Fourth PCB Workshop,Zakopane, Poland and “Nutritional Modulation of Environmental Toxicity: Implications in Atherosclerosis” at Barcelona Biomedical Research Park, Barcelona, Spain.
September '06 Dr.Howard Glauert presented the invited talk "Role of Oxidative Stress in the
Promoting Activities of PCBs" at the Fourth PCB Workshop, Recent Advances in the Environmental Toxicology and Health Effects of PCBs, Zakopane, Poland.
August '06 Dr.David Hildebrand presented the invited talk entitled “Oxylipin Production in Soybeans” at the 2006 Cellular and Molecular Biology of the Soybean at Lincoln, NE.
July '06 GCNS Ph.D. student, Shetty Shoba, has been awarded a two year American Heart Association pre-doctoral fellowship.
July '06 Graduate Center for Nutritional Sciences doctoral student Lei Wang, featured on NIEHS/NIH website. Link
04.10.06 Three faculty of Nutritional Sciences awarded a Program Project Grant from the NIHHeart Lung and Blood Institute entitled "Mechanisms of abdominal aortic aneurysm formation".
11.07.05 Nutritional Sciences rated within the top 10 graduate programs at UK based on graduate student publications, presentations and projects.
07.01.05 Nutritional Sciences receives funding from the USDA (Nutrition and Chronic Disease) and the NIH (Nutrition and Oxidative Stress) to support doctoral student training. LINK
07.01.05 USDA Predoctoral Training Grant in Obesity and Related Diseases (cardiovasculardisease, diabetes, cancer) funded to provide three predoctoral stipends for a three-year period. LINK
06.01.05 NIH T32 Predoctoral Training Grant in Nutrition and Oxidative Stress is renewed to provide three predoctoral stipends for five years of funding. LINK
|
