Lab research generally involves experiments conducted in a laboratory where researchers look to explore and understand the interaction and relationship between various materials or biological matter and/or involve computational analyses. Projects typically do not involve oral health patients directly. Below are our current lab projects, please contact study personnel for more details.
Delivery of Polyphenols in Gum for Treatment of Gingivitis
Principle Investigator: Craig Miller
Sponsor: Four Tigers, LLC
To test the hypothesis that bioactive phytochemicals released from the FBP chewing gum inhibit biofilm and dental plaque formation in humans.
Antimicrobial/Inflammatory Epithelial Resp. Modulated by P. Gingivalis-Induced PLA2-IIA
Principle Investigator: Octavio Gonzalez
Sponsor: National Institutes of Health
Identify the OEC signaling pathways involved in P. gingivalis-induced PLA2-IIA, and determine the cellular location and function of OEC-produced PLA2-IIA in response to P. gingivalis.
In vitro Evaluation of Osteoblast Response on Carbon Nanotube-Coated Titanium Surfaces
Principle Investigator: Karthikeyan Subramani, PhD
Sponsor: American Assoc. of Orthodontists Foundation
The specific aim of this in vitro study is to coat single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) on titanium surfaces (discs) and evaluate osteoblast responses (adhesion, proliferation and differentiation) on CNT-coated titanium substrates.