Interdisciplinary Cardiovascular Training Grant ( T32HL072743)

Program Director:  David Randall, Ph.D.
Co-Director: Alan Daugherty, Ph.D.

The University of Kentucky Interdisciplinary Cardiovascular Training Program will equip young investigators to pursue a long-term research and teaching career in the cardiovascular sciences. The development of our training program over the ~4 years since its inception has been significantly strengthened by: (a) the recent selection by the University of Kentucky central administration of the cardiovascular sciences as an area for focused development; and (b) the establishment of the Cardiovascular Research Center. These new developments have provided our 31 training faculty, administratively housed in 11 academic departments, 3 Colleges and 3 Centers, with a tightly-knit community framework within which to pursue collaborative research and to mentor young scientists. We propose in this application to train 5 pre-doctoral fellows and 4 summer Minority Scholars. Our goal for the latter group is to introduce them to the excitement of research and teaching as a career option; we have been demonstrably successful in this endeavor to date. Our goals for the predoctoral fellows are to:(a) provide rigorous, state-of-the-art education in the basic sciences of the cardiovascular system; (b) provide training in ethical conduct of high quality laboratory research; (c) facilitate translational science by providing our trainees with the requisite tools and experience to compete effectively in this arena; and (d) create future citizens of science by fostering an environment that promotes advocacy of research with highest ethical standards. We accomplish this using a curriculum that combines formal didactic courses, multiple offerings of weekly journal clubs focused upon different aspects of the cardiovascular system, a weekly seminar series, and special events such as our annual Cardiovascular Research Day. Our faculty have extensive and demonstrable experience in co-mentoring of predoctoral fellows; this particularly includes experience of senior faculty in co-mentoring trainees with more junior faculty, thereby helping the latter develop their own careers. The depth and quality of our applicant pool is easily demonstrated by the 23 individuals with solid undergraduate GPA and GRE scores that applied for the 11 positions we have offered to date.

Training Faculty

Douglas Andres, Biochemistry
Dennis Bruemmer, Internal Medicine
Kenneth Campbell, Physiology
Lisa Cassis, Pharmacology
Alan Daugherty, Internal Medicine
Frederick de Beer, Internal Medicine
Brian Delisle, Physiology
Karyn Esser, Physiology
Brandon Fornwalt, Pediatrics and Biomedical Engineering
Ming Gong, Physiology
Greg Graf, Pharmaceutical Sciences
Zhenheng Guo, Internal Medicine
Bernhard Hennig, Animal Sciences
Victoria King, Internal Medicine
Sangderk Lee, Pharmacology
Terry Lennie, College of Nursing
Charles Loftin, Pharmaceutical Sciences
Andrew Morris, Internal Medicine
Debra K. Moser, College of Nursing
Mariana Nikolova-Karakashian, Physiology
Abhijit Patwardhan, Graduate Center Biomedical Engineering
Kevin Pearson, Nutritional Sciences
David Randall, Physiology
Jon Satin, Physiology
Susan Smyth, Internal Medicine
Daret St. Clair, Toxicology
Lisa Tannock, Internal Medicine
Ryan Temel, Pharmacology
Nancy Webb, Internal Medicine

Deneys van der Westhuyzen, Internal Medicine
Craig Vander Kooi, Biochemistry
Sidney Whiteheart, Biochemistry
Changcheng Zhou, Nutritional Sciences


Richard Charnigo, Biostatistics, External Advisory Board
Ada Sue Selwitz, Office of Research Integrity, External Advisory Board

Executive Committee Members

Lisa Cassis, Pharmacology
Alan Daugherty, Internal Medicine
Debra Moser, College of Nursing
Dave Randall, Physiology
Susan Smyth, Internal Medicine
Daret St. Clair, Toxicology
Deneys van der Westhuyzen, Internal Medicine

External Advisory Board

Brian Jackson, Physiology, External Advisory Board
Nobuyo Maeda, University of North Caroline, External Advisory Board
David Polluck, Medical College of Georgia, External Advisory Board
James Tracy, Vice President of Research, External Advisory Board


Brianna Harfmann, Physiology (Karyn Esser)
Robert "Nate" Helsley, Nutritional Sciences (Changcheng Zhou)
Catherine Kaminski, Biochemistry (Doug Andres)
Sonja Pijut, Pharmaceutical Sciences (Gregory Graf)
Greg Wehner, Pediatrics and Biomedical Engineering (Brandon Fornwalt)

Meredith Bostrom, Nutritional Sciences (Nancy Webb)
Emily Bradshaw-Helfrich, Physiology (Eric Smart)
Miranda Byse, Physiology (Jonathon Satin)
Lindsay Calderon, Pharmacology (Ming Gong)
Robert N. Correll, Biochemistry (Douglas Andres)
Shawn Crump, Physiology (Jonathon Satin)
Zachary Fulkerson, Physiology (Susan Smyth)

Randall Hulshizer, Pharmacology (Robert Hadley)
William Lester, Physiology (Jonathon Satin)
Jenny Lutshumba, Physiology (Ming Gong)
Jason Meyer, Biochemistry (Deneys van der Westhuyzen)
Paul Mueller, Physiology (Susan S Smyth)
Matthew Parker, Biochemistry (Craig Vander Kooi)
David Peleshok, Nutritional Sciences (Nancy Webb)
Kelly Putnam,  Nutritional Sciences (Lisa Cassis)
Valerie Reeves, Physiology (David Randall)
Rebecca Scotland, Pharmacology (Steven Post)
Robin Shoemaker, Nutritional Sciences (Lisa Cassis)
Candice Thomas, Nutritional Sciences (David Randall)
Aaron Urbas, Pharmaceutical Sciences (Robert Lodder)
Joyce Valez, Toxicology (Daret St. Clair)
Yanmei Wang, Nutritional Sciences (Reto Asmis)

Trainee Publications

Graduate students working in the laboratory of a training faculty are encouraged to apply for support. Students will be selected based on their GPA, GRE quantitative score and research experience. All qualified graduate student applicants will be interviewed by the members of the recruiting committee and by selected additional individuals from the training faculty. Preference for trainee fellowships will be given to qualified graduate students who have passed their qualifying exam and whose success in graduate programs has already been established. Renewals for additional years support will be contingent on satisfactory performance in the first year.

Candidates must have performed successfully and been recommended by the academic program into which they have matriculated (e.g., IBS). All applicants that meet minimal acceptance standards will be reviewed by the members of the Recruiting and Student Affairs Committee for acceptance into the program, and, upon their recommendation, by the Executive Committee. All candidates must give evidence of firm intention to become an investigator, whether as a basic science or, eventually, a clinical faculty member.

Candidates must
complete a series of basic coursework related to the working a laboratory environment.  These offerings enhance the training experience as part of their overall professional development.  They are described here.

Jan. 2008 Competing Renewal Grant Application (Restricted Access)

University of Kentucky College of Medicine - Cardiovascular Research Center
University of Kentucky - An Equal Opportunity University
Copyright © 2014 University of Kentucky Chandler Medical Center.
Comments: Darin Cecil | Last Modified: 01/08/2014
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