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My current research involves the imaging of brain structures engaged in trigeminal pain processing.
In my first project, brain activity, upon stimulation of the lower jaw with painful heat, was investigated.
It was demonstrated that painful trigeminal stimulation activated brain structures similar to those that are implied in the pain pathways of other body parts.
At this time, I am evaluating whether there are differences in location and extent of brain structures activated by painful stimuli between chronic face pain patients and pain free individuals. At the same time, I am investigating the role of estrogen level on the processing of painful stimuli in chronic face pain patients and pain free individuals. This project is funded by COBRE/WH.
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de Leeuw R, Bertoli E,
Schmidt JE, Carlson CR. Prevalence of major traumatic
stressors in an orofacial pain population. J Oral Maxillofac
Surg 2005;63:42-50
de Leeuw R, Studts JL, Carlson CR. Fatigue and
fatigue related symptoms in an orofacial pain population.
Oral Surg Oral Med Oral Pathol Oral Radiol & Endod
2005;99:168-74
de Leeuw R, Klasser GD, Albuquerque RJC. Are Female
Orofacial Pain patients medically compromised? JADA 2005;136
(4): 459-468.
de Leeuw R, Bertoli E, Schmidt JE, Carlson CR.
Prevalence of Post-Traumatic Stress Disorder Symptoms in
Orofacial Pain Patients. Oral Surg Oral Med Oral Pathol Oral
Radiol & Endod 2005; 99:558-68
de Leeuw R, Albuquerque RJC, Okeson JP, Carlson CR.
The contribution of neuroimaging techniques to the
understanding of supra-spinal pain circuits: implications
for orofacial pain. Oral Surg Oral Med Oral Pathol Oral
Radiol & Endod 2005;100:308-14
Klasser, GD, de Leeuw R. Albuquerque RJC. Self report
health questionnaire: a necessary and reliable tool in
dentistry. General Dentistry September-October
2005;53(5);348-354
de Leeuw R, Schmidt JE, and. Carlson CR. Traumatic
stressors and Post-Traumatic Stress Disorder Symptoms in
Headache Patients. (Accepted for publication in Headache)
de Leeuw R, Albuquerque RJC, Andersen AH, Carlson CR.
Influence of estrogen on brain activation upon painful heat
stimulation: an fMRI study. (Accepted for publication in J
Oral Maxillofac Surgery) |
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Reny de Leeuw,
D.D.S., Ph.D.
Associate Professor
Chief, Division Orofacial Pain
College of Dentistry, D530
University of Kentucky
800 Rose Street
Lexington, KY 40536
Tel: (859) 323-5500
Fax: (859) 323-0001
Email: rdele0@email.uky.edu |
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