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mjnova2@uky.edu |
 Professor of Periodontics
Associate Director, Center for Oral Health Research |
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BDS, Guys Hospital, University of London, England
LDS, RCS. Royal College of Surgeons, England
M.S., University of Rochester, Rochester, NY
Ph.D., University of Rochester, Rochester, NY
Specialty Certification in Periodontics, Eastman Dental Center, Rochester, NY
Diplomate, American Board of Periodontology |
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Curriculum
vitae
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Our overall focus is studying the oral cavity as a source of infection and inflammation that may have an impact on other areas of the body, other medical conditions, and the aging process. In addition, we are developing new ways of treating oral infection and inflammation that may be more cost effective than traditional surgical therapy and, for some patients, more long lasting.
Current areas of interest include:
The effects of periodontal therapy on pre-term birth (University of Kentucky PI, NIH/NIDCR multicenter study)
The effects of aging on oral infection, inflammation and disease (PI, NIH/NIA study)
The
use of host modulation in the treatment of periodontal
disease [PI, FDA Phase IV multicenter study for the use of
subantimicrobial doxycycline (Periostat; CollaGenex
Pharmaceuticals) combined with Atrisorb and scaling and
root planing in
the treatment of periodontal disease]
The
use of host modulation in the treatment of periodontal
disease [PI, FDA Phase III multicenter study for the use
of single
daily dose of subantimicrobial doxycycline (Periostat;
CollaGenex Pharmaceuticals) combined with scaling and root
planing in
the treatment of periodontal disease]
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Yan, SR, and MJ Novak: Src -family Kinase p53/56lyn Plays an Important Role in TNFa-Stimulated Production of O2- by
Human Neutrophils Adherent to Fibrinogen.. Inflammation 23: 2; 167-178, 1999
Yan, SR, and MJ Novak. B2 Integrin-dependent phosphorylation of tyrosine kinase Pyk2 stimulated by TNFa and fMLP in
human neutrophils adherent to fibrinogen. FEBS LETT 451: 33-38, 1999
Yan, SR and MJ Novak. Diverse Effects of Neutrophil Integrin Occupation on Respiratory Burst Activation. Cellular Immunol
195:119-126, 1999
Novak, MJ. Necrotizing Ulcerative Periodontitis. In: Proceedings of the 1999 World Workshop in Periodontics. Annals of
Periodontol 4:74-77, 2000.
Novak, MJ, LP Johns, RC Miller, and MH Bradshaw. Adjunctive benefits of subantimicrobial dose doxycycline in the
management of severe, generalized, chronic periodontitis. J Periodontol 73:762-769, 2002
Novak, MJ, and TG Donley. Advances in dentistry: Using host response modifiers in the treatment of periodontal disease.
Practical Procedures & Aesthetic Dentistry 14:(suppl), 3-10,2002.
Ebersole JL, D Capelli, EC Mathys, MJ Steffen, RE Singer, M
Montgomery, GE Mott, and MJ Novak. Periodontitis in humans
and nonhuman primates: oral systemic linkage inducing acute phase proteins.Ann Periodontol 7:102-111, 2002
Preshaw, PM, AF Hefti, MJ Novak, BS Michalowicz, BL
Pihlstrom, R Schoor, CL Trummel, TE Van Dyke, CB Walker, MH
Bradshaw. Subantimicrobial dose doxycycline enhances
efficacy of scaling and root planing in chronic
periodontitis. J Periodontol
(accepted for publication) 2004 |
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Dr. M. John Novak
Professor and Associate Director
Center for Oral Health Research
University of Kentucky
414 Health Sciences Research Building
Room 401
1095 V.A. Drive
Lexington, KY 40536-0305
Tel: (859) 323-5159
Fax:(859) 257-6566
Email:
mjnova2@uky.edu |
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