xxx

BCH611: Biochemistry and Cell Biology of Nucleic Acids

Syllabus

Dr Wilkerson's lectures

September 2, 2008
 

• Lecture notes (2.55MB MICROSOFT POWERPOINT)

• Supplement (1.02MB MICROSOFT POWERPOINT)

• Articles:

  • Quantitative Nuclear Run-Off Transcription Assay (86KB PDF)
    Authors: Lei Li, Elliot L Chaikof

  • Histone Deacetylase-1 Represses Transcription by Interacting with Zinc-Fingers and Interfering with the DNA Binding Activity of Sp1 (1.61MB PDF)
    Authors: Jae-Eun Kang, Myung-Hwa Kim, Jeong-Ahn Lee, Hyejin Park, Lee Min-Nyung, Chung-Koon Auh, Man-Wook Hur

  • DNAase footprinting: a simple method for the detection of protein-DNA binding specificity (1.74MB PDF)
    Authors: David J Galas, Albert Schmitz

  • Use of Chromatin Immunoprecipitation To Clone Novel E2F Target Promoters (356KB PDF)
    Authors: Amy S Weinmann, Stephanie M Bartley, Theresa Zhang, Michael Q Zhang, Peggy J Farnham

  • Array of hope (88KB PDF)
    Author: Eric S Lander

  • Exon amplification: A strategy to isolate mammalian genes based on RNA splicing (1.40MB PDF)
    Authors: Alan J Buckler, David D Chang, Sharon L Graw, J David Brook, Daniel A Haber, Phillip A Sharp, David E Housman

  • Exploring the new world of the genome with DNA microarrays (803KB PDF)
    Authors: Patrick O Brown, David Botstein

  • The Role of p38 Mitogen-Activated Protein Kinase in IL-1β Transcription (168KB PDF)
    Authors: Joseph J Baldassare, Yanhua Bi, Clifford J Bellone

September 4, 2008

• Lecture notes (3.72MB MICROSOFT POWERPOINT)

• Articles:

  • SUMO fusion technology for difficult-to-express proteins (631KB PDF)
    Authors: Tauseef R Butt, Suzanne C Edavettal, John P Hall, Michael R Mattern

  • Advanced genetic strategies for recombinant protein expression in Escherichia coli (406KB PDF)
    Authors: Hans Peter Sørensen, Kim Kusk Mortensen

  • Baculovirus as versatile vectors for protein expression in insect and mammalian cells (481KB PDF)
    Authors: Thomas A Kost, J Patrick Condreay, Donald L Jarvis

  • Components of Vectors for Gene Transfer and Expression in Mammalian Cells (136KB PDF)
    Author: Savvas C Makrides

  • From gene to protein: a review of new and enabling technologies for multi-parallel protein expression (1.47MB PDF)
    Author: Ian Hunt

  • Proteomics strategies for protein identification (180KB PDF)
    Authors: Katheryn A Resing, Natalie G Ahn

  • New frontiers in proteomics research: A perspective (448KB PDF)
    Authors: Vikas Dhingra, Mukta Gupta, Tracy Andacht, Zhen F Fua

  • RNA interference: the new somatic cell genetics? (269KB PDF)
    Authors: Patrick J Paddison, Gregory J Hannon

  • The Silent Revolution: RNA Interference as Basic Biology, Research Tool, and Therapeutic (503KB PDF)
    Authors: Derek M Dykxhoorn, Judy Lieberman

  • Automation in Genotyping of Single Nucleotide Polymorphisms (403KB PDF)
    Author: Ivo G Gut

  • Methods for Genotyping Single Nucleotide Polymorphisms (314KB PDF)
    Author: Pui-Yan Kwok